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The map label for this gene is mngR [H]

Identifier: 66046364

GI number: 66046364

Start: 3760685

End: 3761428

Strand: Reverse

Name: mngR [H]

Synonym: Psyr_3135

Alternate gene names: 66046364

Gene position: 3761428-3760685 (Counterclockwise)

Preceding gene: 66046365

Following gene: 66046363

Centisome position: 61.73

GC content: 60.08

Gene sequence:

>744_bases
ATGAATAAAATAATGAACAAGCTTTCCAGCGACGAACGTCTACCGCTTTATCAGCGCCTGCGCGACAGCCTGGCGCAACA
GATCGCCAACAATCGCTGGCGTCCGGGTGAGGCGATTCCTACCGAAGCGGCTTTGTCTGCCGAGTATTGCCTGTCCACCG
GCACGGTGCGCAAGGCCATTGATCTGCTGGTCAGTGACAACATTCTGGAGCGTCAGCAGGGGCGTGGCACGTTCATTCGT
CGTGCGCAGTTTCAGTCTTCGCTGTTTCGTTTTTTCCGTTTTCAAACCGAAGCGGGTGAACGCCGGGTGCCGGAAAGCCG
GATTTTGTCCGTCGAGCCTGTGGACGCGCCTTCGTCGGTCGCTCAGGCGTTGGGGATGGCCGCCGGTGCCCCGGTGATTC
GTATGGTCCGCTTGCGGTTGATGGATGGCCAGCCGGTGCTGGCCGAAGAGATCTGGCTGCCACGTGCGCGGTTTCAGGCA
TTGCTGGAGCTTGACCTCGATACGCAGGGGCCATTGCTTTATCCGATCTACGAAGACGCCTGCGGTCAGGTGGTCGCCTG
TGCGCAAGAAAGCCTGACGGCCGAGACGGTCAACGACGTGTACGGCCGGCTGCTGCAGATTCCGGTCGGCAGTGCGGTGG
TGGTCATCGAACGCCTGGCGCTCAATTACGCGGGTGAACCTCTGGAATGGCGTCGTTCGCGAGGGCACGCCAGTCATTTC
CGCTACAGCGTGGAAATTCGCTGA

Upstream 100 bases:

>100_bases
ACGCGATTCATACCTCGATAGCCGGCTGACTGCCGGTTCTTGACGCTTTACGGCATCGCCTCAATAATCAATCTGCTTGA
AAATTCATATAGATGACTGG

Downstream 100 bases:

>100_bases
CAGCGCTGCAGCCTGCCCAAGCTGTTCAACGCCCATAAGGATAAAAGCCATGTTCAGCTGGTATCGCGATGTCACTTCCA
AAGAGCGCAAGACCTTCTGG

Product: transcriptional regulator GntR

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNKIMNKLSSDERLPLYQRLRDSLAQQIANNRWRPGEAIPTEAALSAEYCLSTGTVRKAIDLLVSDNILERQQGRGTFIR
RAQFQSSLFRFFRFQTEAGERRVPESRILSVEPVDAPSSVAQALGMAAGAPVIRMVRLRLMDGQPVLAEEIWLPRARFQA
LLELDLDTQGPLLYPIYEDACGQVVACAQESLTAETVNDVYGRLLQIPVGSAVVVIERLALNYAGEPLEWRRSRGHASHF
RYSVEIR

Sequences:

>Translated_247_residues
MNKIMNKLSSDERLPLYQRLRDSLAQQIANNRWRPGEAIPTEAALSAEYCLSTGTVRKAIDLLVSDNILERQQGRGTFIR
RAQFQSSLFRFFRFQTEAGERRVPESRILSVEPVDAPSSVAQALGMAAGAPVIRMVRLRLMDGQPVLAEEIWLPRARFQA
LLELDLDTQGPLLYPIYEDACGQVVACAQESLTAETVNDVYGRLLQIPVGSAVVVIERLALNYAGEPLEWRRSRGHASHF
RYSVEIR
>Mature_247_residues
MNKIMNKLSSDERLPLYQRLRDSLAQQIANNRWRPGEAIPTEAALSAEYCLSTGTVRKAIDLLVSDNILERQQGRGTFIR
RAQFQSSLFRFFRFQTEAGERRVPESRILSVEPVDAPSSVAQALGMAAGAPVIRMVRLRLMDGQPVLAEEIWLPRARFQA
LLELDLDTQGPLLYPIYEDACGQVVACAQESLTAETVNDVYGRLLQIPVGSAVVVIERLALNYAGEPLEWRRSRGHASHF
RYSVEIR

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=233, Percent_Identity=27.0386266094421, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082252, Length=220, Percent_Identity=24.5454545454545, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790118, Length=235, Percent_Identity=23.8297872340426, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788418, Length=243, Percent_Identity=26.3374485596708, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27798; Mature: 27798

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIMNKLSSDERLPLYQRLRDSLAQQIANNRWRPGEAIPTEAALSAEYCLSTGTVRKAI
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
DLLVSDNILERQQGRGTFIRRAQFQSSLFRFFRFQTEAGERRVPESRILSVEPVDAPSSV
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCCCHHHH
AQALGMAAGAPVIRMVRLRLMDGQPVLAEEIWLPRARFQALLELDLDTQGPLLYPIYEDA
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHH
CGQVVACAQESLTAETVNDVYGRLLQIPVGSAVVVIERLALNYAGEPLEWRRSRGHASHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHE
RYSVEIR
EEEEEEC
>Mature Secondary Structure
MNKIMNKLSSDERLPLYQRLRDSLAQQIANNRWRPGEAIPTEAALSAEYCLSTGTVRKAI
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
DLLVSDNILERQQGRGTFIRRAQFQSSLFRFFRFQTEAGERRVPESRILSVEPVDAPSSV
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCCCHHHH
AQALGMAAGAPVIRMVRLRLMDGQPVLAEEIWLPRARFQALLELDLDTQGPLLYPIYEDA
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHH
CGQVVACAQESLTAETVNDVYGRLLQIPVGSAVVVIERLALNYAGEPLEWRRSRGHASHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHE
RYSVEIR
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]