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The map label for this gene is ttuB [H]

Identifier: 66046348

GI number: 66046348

Start: 3739245

End: 3740591

Strand: Direct

Name: ttuB [H]

Synonym: Psyr_3119

Alternate gene names: 66046348

Gene position: 3739245-3740591 (Clockwise)

Preceding gene: 66046346

Following gene: 66046349

Centisome position: 61.36

GC content: 59.91

Gene sequence:

>1347_bases
GTGAGCACATCCAATTCCAGGATGGCCGACGGCACAGGTTCGGTTCTGAATTCAGCCGTATCGAAGGTCAAACGTCACGT
CCTGCCGCTTTTCGTCATCATGTTCATCGTCAACTACATCGACCGGGTCAACATCGGCTTCGTGCGTTCGCACATGGAGC
ATGACCTGGGTATCGGCGCTGCTGCCTATGGCCTGGGTGCCGGACTGTTTTTCATCGGCTATGCCCTCTTCGAAGTCCCT
TCCAACATCCTGTTGCAGAAAGTCGGCGCACGTATCTGGCTGACGCGGATCATGCTGACCTGGGGCATCGTTGCGGCCTG
CATGGCCTTTATCCAGACCGAAACCCACTTCTACATTTTGCGGTTTCTGCTCGGCGTGGCCGAGGCCGGTTTCTTTCCAG
GCGTGATCTACTACTTCACCCGCTGGCTTCCCGGCGTCGAGCGTGGCAAGGCGATTGCCATCTTCCTCAGCGGTTCGGCC
ATCGCCTCGTTGATCTCGGGCCCGTTGTCCGGCCTGCTGCTGCAAATCACCGGTTTCGGCCTGAAGGGCTGGCAGTGGAT
GTACTTCATCGAAGGCATGTTCTCGGTCGGCCTGTGCTTCTTCGTCTGGTTCTGGCTGGACTCAAACCCGCACGATGCCA
AGTGGCTGACCCGCGAAGAACAGGATGCACTGGTCAACGCCATCGATGCCGAGCAGGCTGCCCGTGAAGCGGCGACGCCG
GTCAAGGCGTCCATCGGCAAGCTGCTCAAGGACGGTCAGATCATTCTGTTCTGCCTGATCTACTTCTTCATCCAGCTGAC
GATTTACGCAGCGACGTTCTGGCTGCCGAGCATCATCCGCAAGATGGGCAGCCTGACTGACTTCGAAGTCGGCATGTTCA
ACTCGATTCCGTGGCTGCTGTCGATCATCGGCATGTACGTGTTCGCCTCGCTGTCCGCCAAGTGGAAACGCCAGCAAGCC
TGGGTAGCCATTGCCCTGCTGATTGCCGCTGCCGGAATGTTCATGTCGACCACCGGCAGCCCGATCTTCGCTTTCGTTGC
CATCTGCTTTGCCGCACTGGGTTTCAAGTCGGCTTCTTCGCTGTTCTGGCCGATCCCGCAGGCCTATCTGGACGCGCGGA
TCGCCGCTGCGGTCATCGCGCTGATCAATTCGGTGGGCAACCTCGGCGGCTTCGTGGCACCGACCACCTTCGGCCTGCTG
GAAGAACACACCGGCTCGATCCAGGGCGGACTGTACGGCCTGACAGCCACTTCGATCATCGCCGCGATCATCGTTTTCGC
CGCGCGCAATACCCCCAAGCCTGGTGCGACGCCGGTCGCCGCCATTCAGACCCCGGCGACCCACTGA

Upstream 100 bases:

>100_bases
AAGGGATTGCACAACGGCTTTTTACTTGTATGATGACCGACAATGCGAGGGACAGACTTCGCACATACCCGCATAAAAAC
AACGAGTGGGAGATTCAACT

Downstream 100 bases:

>100_bases
TGCACGTGCGCAGCCGCTTTTTCATCGGTCATATTTTCAAGGCCTTACATTTAAAGGACCCGTCATGAACATTCAGCAAT
CCAATATCACCAGCAAGGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSTSNSRMADGTGSVLNSAVSKVKRHVLPLFVIMFIVNYIDRVNIGFVRSHMEHDLGIGAAAYGLGAGLFFIGYALFEVP
SNILLQKVGARIWLTRIMLTWGIVAACMAFIQTETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGVERGKAIAIFLSGSA
IASLISGPLSGLLLQITGFGLKGWQWMYFIEGMFSVGLCFFVWFWLDSNPHDAKWLTREEQDALVNAIDAEQAAREAATP
VKASIGKLLKDGQIILFCLIYFFIQLTIYAATFWLPSIIRKMGSLTDFEVGMFNSIPWLLSIIGMYVFASLSAKWKRQQA
WVAIALLIAAAGMFMSTTGSPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLL
EEHTGSIQGGLYGLTATSIIAAIIVFAARNTPKPGATPVAAIQTPATH

Sequences:

>Translated_448_residues
MSTSNSRMADGTGSVLNSAVSKVKRHVLPLFVIMFIVNYIDRVNIGFVRSHMEHDLGIGAAAYGLGAGLFFIGYALFEVP
SNILLQKVGARIWLTRIMLTWGIVAACMAFIQTETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGVERGKAIAIFLSGSA
IASLISGPLSGLLLQITGFGLKGWQWMYFIEGMFSVGLCFFVWFWLDSNPHDAKWLTREEQDALVNAIDAEQAAREAATP
VKASIGKLLKDGQIILFCLIYFFIQLTIYAATFWLPSIIRKMGSLTDFEVGMFNSIPWLLSIIGMYVFASLSAKWKRQQA
WVAIALLIAAAGMFMSTTGSPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLL
EEHTGSIQGGLYGLTATSIIAAIIVFAARNTPKPGATPVAAIQTPATH
>Mature_447_residues
STSNSRMADGTGSVLNSAVSKVKRHVLPLFVIMFIVNYIDRVNIGFVRSHMEHDLGIGAAAYGLGAGLFFIGYALFEVPS
NILLQKVGARIWLTRIMLTWGIVAACMAFIQTETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGVERGKAIAIFLSGSAI
ASLISGPLSGLLLQITGFGLKGWQWMYFIEGMFSVGLCFFVWFWLDSNPHDAKWLTREEQDALVNAIDAEQAAREAATPV
KASIGKLLKDGQIILFCLIYFFIQLTIYAATFWLPSIIRKMGSLTDFEVGMFNSIPWLLSIIGMYVFASLSAKWKRQQAW
VAIALLIAAAGMFMSTTGSPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLLE
EHTGSIQGGLYGLTATSIIAAIIVFAARNTPKPGATPVAAIQTPATH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=385, Percent_Identity=23.3766233766234, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21322234, Length=373, Percent_Identity=24.1286863270777, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI9945322, Length=355, Percent_Identity=21.9718309859155, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI9966811, Length=355, Percent_Identity=22.2535211267606, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=35.8974358974359, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=23.5294117647059, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=25.8426966292135, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=23.2718894009217, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367379, Length=402, Percent_Identity=23.3830845771144, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367193, Length=329, Percent_Identity=21.580547112462, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI86561091, Length=258, Percent_Identity=24.4186046511628, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=333, Percent_Identity=21.3213213213213, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=436, Percent_Identity=22.0183486238532, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323032, Length=238, Percent_Identity=23.9495798319328, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=227, Percent_Identity=22.4669603524229, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=243, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639764, Length=362, Percent_Identity=23.2044198895028, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130167, Length=427, Percent_Identity=20.8430913348946, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24654215, Length=351, Percent_Identity=24.2165242165242, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922400, Length=351, Percent_Identity=24.2165242165242, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641682, Length=383, Percent_Identity=21.9321148825065, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48682; Mature: 48551

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSNSRMADGTGSVLNSAVSKVKRHVLPLFVIMFIVNYIDRVNIGFVRSHMEHDLGIGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
AAYGLGAGLFFIGYALFEVPSNILLQKVGARIWLTRIMLTWGIVAACMAFIQTETHFYIL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFLLGVAEAGFFPGVIYYFTRWLPGVERGKAIAIFLSGSAIASLISGPLSGLLLQITGFG
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
LKGWQWMYFIEGMFSVGLCFFVWFWLDSNPHDAKWLTREEQDALVNAIDAEQAAREAATP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC
VKASIGKLLKDGQIILFCLIYFFIQLTIYAATFWLPSIIRKMGSLTDFEVGMFNSIPWLL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHH
SIIGMYVFASLSAKWKRQQAWVAIALLIAAAGMFMSTTGSPIFAFVAICFAALGFKSASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
LFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLLEEHTGSIQGGLYGLTATSII
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AAIIVFAARNTPKPGATPVAAIQTPATH
HHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
STSNSRMADGTGSVLNSAVSKVKRHVLPLFVIMFIVNYIDRVNIGFVRSHMEHDLGIGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
AAYGLGAGLFFIGYALFEVPSNILLQKVGARIWLTRIMLTWGIVAACMAFIQTETHFYIL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFLLGVAEAGFFPGVIYYFTRWLPGVERGKAIAIFLSGSAIASLISGPLSGLLLQITGFG
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
LKGWQWMYFIEGMFSVGLCFFVWFWLDSNPHDAKWLTREEQDALVNAIDAEQAAREAATP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC
VKASIGKLLKDGQIILFCLIYFFIQLTIYAATFWLPSIIRKMGSLTDFEVGMFNSIPWLL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHH
SIIGMYVFASLSAKWKRQQAWVAIALLIAAAGMFMSTTGSPIFAFVAICFAALGFKSASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
LFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLLEEHTGSIQGGLYGLTATSII
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AAIIVFAARNTPKPGATPVAAIQTPATH
HHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]