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The map label for this gene is hlyB [H]

Identifier: 66046343

GI number: 66046343

Start: 3731745

End: 3733370

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_3114

Alternate gene names: 66046343

Gene position: 3733370-3731745 (Counterclockwise)

Preceding gene: 66046344

Following gene: 66046342

Centisome position: 61.27

GC content: 60.82

Gene sequence:

>1626_bases
ATGAATCTACGCAAACTCACTATCGCTCGTCGTGCCGGTCTGGGTTTTACCCTTATTTCCCTGCTGGTGGCATTGCTGGG
GTGGTTTGCGCTGGCGCAGATGTCGACCATCCGGCAGAGTGAAGTGGCGGTGGAGACCAACTGGCTGCCCAGCATGCGAG
TGGTCAACGATATCCGCGAAATCATGCTGCGCATTCGGACCATTTCCTTGCGCATGGCACTGGACACCGATCCTGCGAGT
ATTCCGACCTACCGTGGTCAGATGGATGTGCGTCTGGGCGATCTGGACAAGAAGCTGTCTGTCCTCAAGACCTTTGTCGA
CACCCCGGAAGAGAAGTCGCTGACCGACCAGTTCATGGTGACCGTGGGCCAATACCGCAGTGCGCTGGACCGTTCCTTTG
CACTGGCCAGCCAGGGCGACAGCGTCGGGCTGAACAAGCTGCTGCTGGTCGACATGAAGCAGATCGTCGACGGTTCCGGC
AAGCAACTCGGTGACCTGGCCGACTTCTATCTCACTCAGGTCGATGCGGAAGGCAAGTCGGCCGGGGCCCAGTACGACAA
GTCGCGCGACATCGTCATTATCTTTGTGGTCATTGCCGCGCTGTGCACCATCGGCCTGGCACTCTGGCTGACCCGCAGCA
TCGTCGGCCCGCTGCAACGTGCAGTAACCGCCGCCGAGCAGGTTGCCAACGGCGACCTGACCCATACCATCGAAGTCGAT
GGCGAAGACGAAGTCACCCGACTGTTGCGTGCCCTGGCGATGATGCAGGTCAATCTGCGTGAAGCCATGCGCCACATCGG
CAGTTCGGCCACTCAACTGGCATCGGCCGCCACCGAACTCAACTCGGTTACCGAAGACAGCTACCGCGGGCTGAACCAGC
AGAATGCGGAGATCGACCAGGCCGCCACAGCGATCAACGAAATGACCTCGGCAGTCGAGGAAGTTGCGCGTAACGCCGTA
TCCACGTCGGACGCCTCCAACCAGTCCAGTACCTCGGCATTGGCGGGCCAGACGCGGGTGATCGAGACGGTGCAGTCGAT
CCAGACGCTGACCGACAACGTGCAGGCCACCTCGACGCTGGTGCAAAACCTTGCCAATCAGTCGCAGGACATCGGCAAAG
TGCTGGACGTGATCCGCTCGATTGCCGAGCAGACCAACCTGTTGGCACTCAACGCCGCCATCGAAGCGGCACGTGCAGGC
GAGTCGGGCCGTGGTTTCGCGGTGGTGGCGGACGAAGTCCGCGCATTGGCGCATCGCACCCAGCAGTCGACGCTGGAAAT
CGATTCGATGGTCAGCGCCATGCGCAGCGGTTCAGCGCAGGCGCTCGACTCGATGAACACCAGCCGCGCTCGGGCCGACT
CGACATTGGCACTGGCCAAGGGCGCGGGCGAGTCCTTGAGCGAAATCACCTCGTCGATCAATCAGATCTCCGAGCGCAAT
CTGGTGATTGCCAGCGCGGCGGAAGAGCAGGCGCAGGTCTCGCGTGAAGTCGACCGCAACATCGTCAACATTCGCGATCT
GTCCATGCAGTCGACTCAGGGTGCCAACCAGATCAGTGCGTCGAGCCATGAATTGTCGCGTCTGGCGGCCGATCTGAATC
AGGTGGTCTCACGCTTCAAGGTGTAA

Upstream 100 bases:

>100_bases
TGGGCGTCCTAAAGAATTATTTGATCAGGGCGATACGCTGTCGGTTGTCTGACAACTTCGTGTCGGGCACTGCCCTCAAA
AAATATAAAGAGCCCTGGTC

Downstream 100 bases:

>100_bases
AACCCTACATTGATACAGGTTGTGTCCGCTTGCCGACGATCGACCGGACGCGCATTATGCCCTCGGTCGAAATGACCTCC
GGTACAGTCTGGGCACAACC

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPAS
IPTYRGQMDVRLGDLDKKLSVLKTFVDTPEEKSLTDQFMVTVGQYRSALDRSFALASQGDSVGLNKLLLVDMKQIVDGSG
KQLGDLADFYLTQVDAEGKSAGAQYDKSRDIVIIFVVIAALCTIGLALWLTRSIVGPLQRAVTAAEQVANGDLTHTIEVD
GEDEVTRLLRALAMMQVNLREAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAV
STSDASNQSSTSALAGQTRVIETVQSIQTLTDNVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAG
ESGRGFAVVADEVRALAHRTQQSTLEIDSMVSAMRSGSAQALDSMNTSRARADSTLALAKGAGESLSEITSSINQISERN
LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVSRFKV

Sequences:

>Translated_541_residues
MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPAS
IPTYRGQMDVRLGDLDKKLSVLKTFVDTPEEKSLTDQFMVTVGQYRSALDRSFALASQGDSVGLNKLLLVDMKQIVDGSG
KQLGDLADFYLTQVDAEGKSAGAQYDKSRDIVIIFVVIAALCTIGLALWLTRSIVGPLQRAVTAAEQVANGDLTHTIEVD
GEDEVTRLLRALAMMQVNLREAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAV
STSDASNQSSTSALAGQTRVIETVQSIQTLTDNVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAG
ESGRGFAVVADEVRALAHRTQQSTLEIDSMVSAMRSGSAQALDSMNTSRARADSTLALAKGAGESLSEITSSINQISERN
LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVSRFKV
>Mature_541_residues
MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIREIMLRIRTISLRMALDTDPAS
IPTYRGQMDVRLGDLDKKLSVLKTFVDTPEEKSLTDQFMVTVGQYRSALDRSFALASQGDSVGLNKLLLVDMKQIVDGSG
KQLGDLADFYLTQVDAEGKSAGAQYDKSRDIVIIFVVIAALCTIGLALWLTRSIVGPLQRAVTAAEQVANGDLTHTIEVD
GEDEVTRLLRALAMMQVNLREAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQAATAINEMTSAVEEVARNAV
STSDASNQSSTSALAGQTRVIETVQSIQTLTDNVQATSTLVQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAG
ESGRGFAVVADEVRALAHRTQQSTLEIDSMVSAMRSGSAQALDSMNTSRARADSTLALAKGAGESLSEITSSINQISERN
LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVSRFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=35.4838709677419, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788194, Length=365, Percent_Identity=31.7808219178082, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787690, Length=348, Percent_Identity=32.183908045977, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788195, Length=317, Percent_Identity=31.5457413249211, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1789453, Length=339, Percent_Identity=28.9085545722714, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58257; Mature: 58257

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIRE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
IMLRIRTISLRMALDTDPASIPTYRGQMDVRLGDLDKKLSVLKTFVDTPEEKSLTDQFMV
HHHHHHHHHEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHH
TVGQYRSALDRSFALASQGDSVGLNKLLLVDMKQIVDGSGKQLGDLADFYLTQVDAEGKS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
AGAQYDKSRDIVIIFVVIAALCTIGLALWLTRSIVGPLQRAVTAAEQVANGDLTHTIEVD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GEDEVTRLLRALAMMQVNLREAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AATAINEMTSAVEEVARNAVSTSDASNQSSTSALAGQTRVIETVQSIQTLTDNVQATSTL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRT
HHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
QQSTLEIDSMVSAMRSGSAQALDSMNTSRARADSTLALAKGAGESLSEITSSINQISERN
HHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVSRFK
EEEEECHHHHHHHHHHHHHHHCCHHHCCCHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure
MNLRKLTIARRAGLGFTLISLLVALLGWFALAQMSTIRQSEVAVETNWLPSMRVVNDIRE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
IMLRIRTISLRMALDTDPASIPTYRGQMDVRLGDLDKKLSVLKTFVDTPEEKSLTDQFMV
HHHHHHHHHEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHH
TVGQYRSALDRSFALASQGDSVGLNKLLLVDMKQIVDGSGKQLGDLADFYLTQVDAEGKS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
AGAQYDKSRDIVIIFVVIAALCTIGLALWLTRSIVGPLQRAVTAAEQVANGDLTHTIEVD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GEDEVTRLLRALAMMQVNLREAMRHIGSSATQLASAATELNSVTEDSYRGLNQQNAEIDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AATAINEMTSAVEEVARNAVSTSDASNQSSTSALAGQTRVIETVQSIQTLTDNVQATSTL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQNLANQSQDIGKVLDVIRSIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRALAHRT
HHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
QQSTLEIDSMVSAMRSGSAQALDSMNTSRARADSTLALAKGAGESLSEITSSINQISERN
HHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
LVIASAAEEQAQVSREVDRNIVNIRDLSMQSTQGANQISASSHELSRLAADLNQVVSRFK
EEEEECHHHHHHHHHHHHHHHCCHHHCCCHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]