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The map label for this gene is cusC [H]

Identifier: 66046312

GI number: 66046312

Start: 3688696

End: 3690168

Strand: Reverse

Name: cusC [H]

Synonym: Psyr_3083

Alternate gene names: 66046312

Gene position: 3690168-3688696 (Counterclockwise)

Preceding gene: 66046315

Following gene: 66046311

Centisome position: 60.56

GC content: 63.41

Gene sequence:

>1473_bases
ATGCCGATGAGTACACCGCTGTCCAAGCGTATCCGCAACCGCCGCCGGTATGGCCTGGCCATGCTGGCGAGCCTGGTTCT
TTCGGGCTGCTCGTTGATACCGGCCTATCAGCGTCCAGCGTTGCCGGTCCCTGTCGATCAGGTGTCTGCTGTTGTCCGGG
CCTCGAGTACTTCCGCCGACCTGACGCTCACTGCCGACGAAGAAGCGCTCGCTGCCGAGTTGTCGCCAAAGGGAGAGCTG
CGCGGGCTGCTGCAATCGGCTCTGGCGTTCAATCGCGATTTTCGTGTGGCGGTGCTGCGTGTGGAGGAGGCCAGGGCAAT
GCGCGGCATCACCCGTGCCGATCGTTTTCCGACCCTTGCTGCAGGTGTCGAGCGCGATCGTCAGCACTTCGATAATGCGG
CCGCCGACGAGCGTTATGGCCAGGACATTTCCATCGCGTCGGTGGGCGTCTCTGACTTCGAACTGGATTTCTTCGGGCGC
GTGCGTAGCCTGTCGGAGGCGGCGCGGCACGATTATCTGGCCAGCACCTACGGCCAGCAGGCGGCACGCAGTGCGCTGAT
TGCGGAAGTCGCCCGCGCCTGGCTGGCCGAGCGTCTGGCCGCCGCCGTGCAGCAGGATGCGCAGGCGGTGCACGAGGCGC
GGCTGATGCTGGTCAAGGCGGCCGAAGAGCAGCAGCGTCAAGGTGCACTTTCGCTGGACGATCTGATGGTTCAGCGCCTC
GACACTCTGACCGCGCAACAGCAGGTACAGGATGCGGCAAGCGATCACGCCAACGCGTGGCAGGCCTTGTTGTTGCTTAC
CGGCTATTCGACAGCGTTGCCCGCGACTAAGCCAGATACCCCTGAGCTGACCGCCGCGTTGGTCGAGACGCCGGCCTGGC
TGTCGAATCTGCCGTCTCAGCGTCTGCTGGAGCGTTTTGACATCCGCCAGCGCGAAGAAGCGCTCAAGGCCAGCAATGCC
AACATTGGTGCTGCCCGTGCGGCGTTCTTTCCGTCCATAAAACTCAGTACCGGCGTGGGCTTGCAGAGCGACAGCCTGCG
CACCTTGTTCAGCAACGGCAGCGGTGCCTGGCTGTTCACCCCGCAATTGAATCTGCCGCTGTTCGACGGCGGGCGTAATC
AGGCCAACCTGGATCTTGCCAAGGTGCGTCAGCAGATCGCGGTGGCCGAGTATGAAAAGGCCGTGCAGAACGCCTTCCGT
GAAATGTCCGCCGTGCTGACCCGCCGTGAGCAGGCCCTGAACCAGATCCGCAACGAGGTCGAGCGGGTGGCGCTGGTCCA
GGAAAAAGTGCGGCGCCTGTCCTTTGAACTCAATGCGGGCGCCGTCGAGCGCACGGCATTGCTGGTTTCCACTCTCCGTA
TTGCCGAAGCCGACGCAGCCGCTCGCAAGTCCCTCGATGCGCTGCAGCAAAACCGCATCGATGTGTTTCGAGTGCTGCAC
GGAGCAGAACCGACAACCCCACCCCAATCCTGA

Upstream 100 bases:

>100_bases
ACGAGCGCGCCTCTTGATCAAATCTTGATAATTCACGAACGGTTTGTTGAAAGTCGACGTTCAGGATGCTGCCCAGAGCC
CACTGTCGCGGACAGATCCT

Downstream 100 bases:

>100_bases
ATGAAACCGGAGTATCCCCATGAGCCCTGCAATCTCTCGTACTCACCTGCGCTCTGCGCTGCTTAAACCTGTGCTGACCG
TGTTGATCACCTCTGCGGCC

Product: RND efflux system, outer membrane lipoprotein, NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPMSTPLSKRIRNRRRYGLAMLASLVLSGCSLIPAYQRPALPVPVDQVSAVVRASSTSADLTLTADEEALAAELSPKGEL
RGLLQSALAFNRDFRVAVLRVEEARAMRGITRADRFPTLAAGVERDRQHFDNAAADERYGQDISIASVGVSDFELDFFGR
VRSLSEAARHDYLASTYGQQAARSALIAEVARAWLAERLAAAVQQDAQAVHEARLMLVKAAEEQQRQGALSLDDLMVQRL
DTLTAQQQVQDAASDHANAWQALLLLTGYSTALPATKPDTPELTAALVETPAWLSNLPSQRLLERFDIRQREEALKASNA
NIGAARAAFFPSIKLSTGVGLQSDSLRTLFSNGSGAWLFTPQLNLPLFDGGRNQANLDLAKVRQQIAVAEYEKAVQNAFR
EMSAVLTRREQALNQIRNEVERVALVQEKVRRLSFELNAGAVERTALLVSTLRIAEADAAARKSLDALQQNRIDVFRVLH
GAEPTTPPQS

Sequences:

>Translated_490_residues
MPMSTPLSKRIRNRRRYGLAMLASLVLSGCSLIPAYQRPALPVPVDQVSAVVRASSTSADLTLTADEEALAAELSPKGEL
RGLLQSALAFNRDFRVAVLRVEEARAMRGITRADRFPTLAAGVERDRQHFDNAAADERYGQDISIASVGVSDFELDFFGR
VRSLSEAARHDYLASTYGQQAARSALIAEVARAWLAERLAAAVQQDAQAVHEARLMLVKAAEEQQRQGALSLDDLMVQRL
DTLTAQQQVQDAASDHANAWQALLLLTGYSTALPATKPDTPELTAALVETPAWLSNLPSQRLLERFDIRQREEALKASNA
NIGAARAAFFPSIKLSTGVGLQSDSLRTLFSNGSGAWLFTPQLNLPLFDGGRNQANLDLAKVRQQIAVAEYEKAVQNAFR
EMSAVLTRREQALNQIRNEVERVALVQEKVRRLSFELNAGAVERTALLVSTLRIAEADAAARKSLDALQQNRIDVFRVLH
GAEPTTPPQS
>Mature_489_residues
PMSTPLSKRIRNRRRYGLAMLASLVLSGCSLIPAYQRPALPVPVDQVSAVVRASSTSADLTLTADEEALAAELSPKGELR
GLLQSALAFNRDFRVAVLRVEEARAMRGITRADRFPTLAAGVERDRQHFDNAAADERYGQDISIASVGVSDFELDFFGRV
RSLSEAARHDYLASTYGQQAARSALIAEVARAWLAERLAAAVQQDAQAVHEARLMLVKAAEEQQRQGALSLDDLMVQRLD
TLTAQQQVQDAASDHANAWQALLLLTGYSTALPATKPDTPELTAALVETPAWLSNLPSQRLLERFDIRQREEALKASNAN
IGAARAAFFPSIKLSTGVGLQSDSLRTLFSNGSGAWLFTPQLNLPLFDGGRNQANLDLAKVRQQIAVAEYEKAVQNAFRE
MSAVLTRREQALNQIRNEVERVALVQEKVRRLSFELNAGAVERTALLVSTLRIAEADAAARKSLDALQQNRIDVFRVLHG
AEPTTPPQS

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=476, Percent_Identity=36.1344537815126, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI2367348, Length=150, Percent_Identity=36, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53613; Mature: 53482

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSTPLSKRIRNRRRYGLAMLASLVLSGCSLIPAYQRPALPVPVDQVSAVVRASSTSAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LTLTADEEALAAELSPKGELRGLLQSALAFNRDFRVAVLRVEEARAMRGITRADRFPTLA
EEEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHH
AGVERDRQHFDNAAADERYGQDISIASVGVSDFELDFFGRVRSLSEAARHDYLASTYGQQ
HHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARSALIAEVARAWLAERLAAAVQQDAQAVHEARLMLVKAAEEQQRQGALSLDDLMVQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DTLTAQQQVQDAASDHANAWQALLLLTGYSTALPATKPDTPELTAALVETPAWLSNLPSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHCCHHHHCCCHH
RLLERFDIRQREEALKASNANIGAARAAFFPSIKLSTGVGLQSDSLRTLFSNGSGAWLFT
HHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCEECCCCCCCCCHHHHHHCCCCCCEEEC
PQLNLPLFDGGRNQANLDLAKVRQQIAVAEYEKAVQNAFREMSAVLTRREQALNQIRNEV
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVALVQEKVRRLSFELNAGAVERTALLVSTLRIAEADAAARKSLDALQQNRIDVFRVLH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEPTTPPQS
CCCCCCCCCC
>Mature Secondary Structure 
PMSTPLSKRIRNRRRYGLAMLASLVLSGCSLIPAYQRPALPVPVDQVSAVVRASSTSAD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LTLTADEEALAAELSPKGELRGLLQSALAFNRDFRVAVLRVEEARAMRGITRADRFPTLA
EEEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHH
AGVERDRQHFDNAAADERYGQDISIASVGVSDFELDFFGRVRSLSEAARHDYLASTYGQQ
HHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARSALIAEVARAWLAERLAAAVQQDAQAVHEARLMLVKAAEEQQRQGALSLDDLMVQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DTLTAQQQVQDAASDHANAWQALLLLTGYSTALPATKPDTPELTAALVETPAWLSNLPSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHCCHHHHCCCHH
RLLERFDIRQREEALKASNANIGAARAAFFPSIKLSTGVGLQSDSLRTLFSNGSGAWLFT
HHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCEECCCCCCCCCHHHHHHCCCCCCEEEC
PQLNLPLFDGGRNQANLDLAKVRQQIAVAEYEKAVQNAFREMSAVLTRREQALNQIRNEV
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVALVQEKVRRLSFELNAGAVERTALLVSTLRIAEADAAARKSLDALQQNRIDVFRVLH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEPTTPPQS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]