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The map label for this gene is hvrB [H]

Identifier: 66046304

GI number: 66046304

Start: 3672773

End: 3673684

Strand: Reverse

Name: hvrB [H]

Synonym: Psyr_3073

Alternate gene names: 66046304

Gene position: 3673684-3672773 (Counterclockwise)

Preceding gene: 66046305

Following gene: 66046303

Centisome position: 60.29

GC content: 55.81

Gene sequence:

>912_bases
ATGACAATGACTCCAGTGGATGGATCGGCTACCTTCGAGGTTAATAACCTGTTCAGAAACCCCAGGATCTGTTTTGACTG
GGAGGACCTGCGTTACTTCGTGATGTTTTCCACGGTCAGCTCCCTGAGTGGCGCTGCAAGGATGCTGGGTGTGGAGCACG
CCACTGTGTCACGCCGTATCGCTTCGCTGGAGAAGTCTCTGAATGTAAAGCTTGTCGATCGTCGCAAGCGGTTGTACGAA
CTGACGGATGAGGGACGGCGTGTGGCGGCGATCGGGCGACAGATCGAGGCGCAGACTCAGGCTGTTGGCCGTCTCGCGGT
TGCGGCTCAGGTGGTGCAGGGTGTGGAGGTGACCATCAGTGCGCCGCCGTCGGTGGCGGTCGAGAAGTTGGTGCCGCAAT
TGGGGGCGTTTCGGGCGATGCATCCCGGTATTGTGTTGCGGTTGTTGGGCGATCATCAGTATTCGTCGTTATCCAGCTGC
CAGTCTGACCTGTGTATACGGTTTTCCAGACCTGTTGAAAGCGGTATCGTCGCGCGGCGGATTGGCACGGCTTCCTTTTC
ATTTTATTGCGCACGTTTTTATCTGGAGCAACGCCCTCCGGAGCATTACGAGTTTATTGCTTATGACAATGAACTGATGA
GTGACAGTCAGAACGGTTGGTTGAGGGATATCGTCGGTGATCGACCCTTTGTGCTGGAGGCCAAAACGGTGGAGTTGCAA
ATTCGTGCTGCGGAAACCGGTGTGGGCATCGCGTTACTGCCCAGTTTTGCCGTAGAGGATAATAATCGTCTGTGCCGGGT
GGAGTTGTCTGCTCCGCTGGAAGTCGATGTCTGGCTGGGCGTGCATGAAGACCTGCGCGCGGTGGCTTCCATCCAGGCTG
CCATGAACTATGTGGAAAGCTGTTATCGCTAG

Upstream 100 bases:

>100_bases
TTGTCAGCCTTATCCTTATCGTTCCACGCACCTGCCAATGCTCGGTTTAAAACATAACAGAACTACCTATTCGCACGAAC
CGCATAAGGATAAGGCTTGG

Downstream 100 bases:

>100_bases
CCAGGGCTGAGTTCACGCTGATTGTGTTGGCGGAAAAACAGTCTTGCGGTGAAAAAATTCACATCCCCTCATCAAATATC
GACAGTTTACAAGTTGGACT

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTMTPVDGSATFEVNNLFRNPRICFDWEDLRYFVMFSTVSSLSGAARMLGVEHATVSRRIASLEKSLNVKLVDRRKRLYE
LTDEGRRVAAIGRQIEAQTQAVGRLAVAAQVVQGVEVTISAPPSVAVEKLVPQLGAFRAMHPGIVLRLLGDHQYSSLSSC
QSDLCIRFSRPVESGIVARRIGTASFSFYCARFYLEQRPPEHYEFIAYDNELMSDSQNGWLRDIVGDRPFVLEAKTVELQ
IRAAETGVGIALLPSFAVEDNNRLCRVELSAPLEVDVWLGVHEDLRAVASIQAAMNYVESCYR

Sequences:

>Translated_303_residues
MTMTPVDGSATFEVNNLFRNPRICFDWEDLRYFVMFSTVSSLSGAARMLGVEHATVSRRIASLEKSLNVKLVDRRKRLYE
LTDEGRRVAAIGRQIEAQTQAVGRLAVAAQVVQGVEVTISAPPSVAVEKLVPQLGAFRAMHPGIVLRLLGDHQYSSLSSC
QSDLCIRFSRPVESGIVARRIGTASFSFYCARFYLEQRPPEHYEFIAYDNELMSDSQNGWLRDIVGDRPFVLEAKTVELQ
IRAAETGVGIALLPSFAVEDNNRLCRVELSAPLEVDVWLGVHEDLRAVASIQAAMNYVESCYR
>Mature_302_residues
TMTPVDGSATFEVNNLFRNPRICFDWEDLRYFVMFSTVSSLSGAARMLGVEHATVSRRIASLEKSLNVKLVDRRKRLYEL
TDEGRRVAAIGRQIEAQTQAVGRLAVAAQVVQGVEVTISAPPSVAVEKLVPQLGAFRAMHPGIVLRLLGDHQYSSLSSCQ
SDLCIRFSRPVESGIVARRIGTASFSFYCARFYLEQRPPEHYEFIAYDNELMSDSQNGWLRDIVGDRPFVLEAKTVELQI
RAAETGVGIALLPSFAVEDNNRLCRVELSAPLEVDVWLGVHEDLRAVASIQAAMNYVESCYR

Specific function: Functions as a low-light activator of ahcY expression (gene for S-adenosyl-L-homocysteine hydrolase) and as a high-light activator of a uncharacterized 21.6 kDa protein in the ahcY-hvrB intergenic region (orf5). It is also a negative regulator of its own

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=250, Percent_Identity=25.6, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=23.7903225806452, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789173, Length=194, Percent_Identity=31.4432989690722, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=177, Percent_Identity=30.5084745762712, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33807; Mature: 33676

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTPVDGSATFEVNNLFRNPRICFDWEDLRYFVMFSTVSSLSGAARMLGVEHATVSRRI
CCCCCCCCCCEEEEHHHHCCCCEEEEHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHH
ASLEKSLNVKLVDRRKRLYELTDEGRRVAAIGRQIEAQTQAVGRLAVAAQVVQGVEVTIS
HHHHHHCCEEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
APPSVAVEKLVPQLGAFRAMHPGIVLRLLGDHQYSSLSSCQSDLCIRFSRPVESGIVARR
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCHHHCHHHHH
IGTASFSFYCARFYLEQRPPEHYEFIAYDNELMSDSQNGWLRDIVGDRPFVLEAKTVELQ
HCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCCCCHHHHCCCCCEEEEEEEEEEE
IRAAETGVGIALLPSFAVEDNNRLCRVELSAPLEVDVWLGVHEDLRAVASIQAAMNYVES
EEEECCCCCEEEECCEEECCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
CYR
HCC
>Mature Secondary Structure 
TMTPVDGSATFEVNNLFRNPRICFDWEDLRYFVMFSTVSSLSGAARMLGVEHATVSRRI
CCCCCCCCCEEEEHHHHCCCCEEEEHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHH
ASLEKSLNVKLVDRRKRLYELTDEGRRVAAIGRQIEAQTQAVGRLAVAAQVVQGVEVTIS
HHHHHHCCEEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
APPSVAVEKLVPQLGAFRAMHPGIVLRLLGDHQYSSLSSCQSDLCIRFSRPVESGIVARR
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCHHHCHHHHH
IGTASFSFYCARFYLEQRPPEHYEFIAYDNELMSDSQNGWLRDIVGDRPFVLEAKTVELQ
HCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCCCCHHHHCCCCCEEEEEEEEEEE
IRAAETGVGIALLPSFAVEDNNRLCRVELSAPLEVDVWLGVHEDLRAVASIQAAMNYVES
EEEECCCCCEEEECCEEECCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
CYR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8282711 [H]