Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 66046209

GI number: 66046209

Start: 3570625

End: 3571899

Strand: Reverse

Name: zraS [C]

Synonym: Psyr_2978

Alternate gene names: 66046209

Gene position: 3571899-3570625 (Counterclockwise)

Preceding gene: 66046210

Following gene: 66046207

Centisome position: 58.62

GC content: 60.55

Gene sequence:

>1275_bases
ATGCCATTGCATTCGGCTGAGCAGGATCGCGAAGTCGCGCAGTACATCGACGCCTTGCGTGAAAGCGAGCGTCAGTTCAG
GACATTGGCTGACAACATGAGCCAATTGGCCTGGACTGCCAGCCCCCGAGGGCAGGTCCACTGGTACAACGAGCGTTGGT
ATGCCTACACCGGTGCCTCGCTTGAGGCCATGACGGCCTTGGGCTGGCGCTCGGTTCTGCATCCTGAGCATCGCGAGCGG
GTGATGGCGCGTTTGCAATACTGCTTTTCCACCGGTTCGATCTGGGAAGATACCTTCCCGATCCGTGGCAAGGACGGTGC
GTTCAACTGGTTCCTGTCGCGCGCGTTACCCCTGCGCGATGCGCGGGGCCACATCACCCACTGGCTGGGTACTCACACCG
ATATCACCGCTCAGGTCAATGCAGAAGAGGCGTTGCGCGAACTCAACGAGAGTCTTGAGTTACGCGTCGCCGAGCGTACG
CGTGAGCTGGAAACCGCCAATAAGTTGCTGCAGGCCGAAATTGCCGAGCGGGCGATGGCTGAGGAGGCCTTGCGTCATGC
GCAGAAGATGGATGCGATCGGTCAGTTGACCGGGGGCATCGCCCATGACTTCAACAATGTACTTTCCGGCGTGATTGGCG
CACTGGACATGATCAGGCTGCGTGTAGCGGCCGGGCGGATCGGTGAGGTCGCGCGCTACCTGGATGCGGCAGCGAGCTCG
GCGAACCGTGCTGCCGCGCTGACCCGCAGGCTGCTGACATTTGCCCGCCGGCAGTCGCTCAACGTCACTGTAGTGGACGT
CAATTGCATGGTCCGCTCCATGGAGGAGCTGTTGCGAGGCACGGTCGGCGCTCATGCGCATCTGGAGATCGAGCTGGAGG
AGGGGTTGAGCGCGGTGCGCACCGATGAGCACCAGCTGGAAAATGCCTTGTTGAATCTGGTCATCAACGCTCGCGATGCT
GTGCCTGTCGGAGGGAGGCTGTGCGTGCGCAGTCGCTCGTTAACACTGGCGGCGCAAAAAGAGGGTTTGCTGCCTGGCGA
CTACATACAGCTCAGTGTTGAAGATAACGGCTGTGGCATTGCTCAGGACGTTATCGACCAGGTGTTCGACCCGTTTTTCA
CCACCAAACCGGTAGGTCAGGGAACCGGGCTGGGTTTGTCGATGGTCTACGGCTTTACCCGGCAGAGTGGCGGGCACGTG
CATATAGAAAGCACTGAAGGTCAGGGCACCCGGGTTCATTTGCAGCTGCCATGCGGCAAGGCTGCGGTTGCCTGA

Upstream 100 bases:

>100_bases
AACGTTAAGTCACGCAGCGCCCGGAGTTCAGGAAGAGCTCCGGGGTAAAGGCTTGAAGAGGATGGATCCCGACGTGAATA
GAGAACAACCACCGGCCAGA

Downstream 100 bases:

>100_bases
AGCTTCTGGTCATGGCTTGTTCGATGGCTTCTTTCCGGTGGCTTTAGGCTTGTCCGGCTGATCGAGCCTGATCTGCAGGT
TCTCCAGTGCTGCTTCCTTC

Product: PAS

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MPLHSAEQDREVAQYIDALRESERQFRTLADNMSQLAWTASPRGQVHWYNERWYAYTGASLEAMTALGWRSVLHPEHRER
VMARLQYCFSTGSIWEDTFPIRGKDGAFNWFLSRALPLRDARGHITHWLGTHTDITAQVNAEEALRELNESLELRVAERT
RELETANKLLQAEIAERAMAEEALRHAQKMDAIGQLTGGIAHDFNNVLSGVIGALDMIRLRVAAGRIGEVARYLDAAASS
ANRAAALTRRLLTFARRQSLNVTVVDVNCMVRSMEELLRGTVGAHAHLEIELEEGLSAVRTDEHQLENALLNLVINARDA
VPVGGRLCVRSRSLTLAAQKEGLLPGDYIQLSVEDNGCGIAQDVIDQVFDPFFTTKPVGQGTGLGLSMVYGFTRQSGGHV
HIESTEGQGTRVHLQLPCGKAAVA

Sequences:

>Translated_424_residues
MPLHSAEQDREVAQYIDALRESERQFRTLADNMSQLAWTASPRGQVHWYNERWYAYTGASLEAMTALGWRSVLHPEHRER
VMARLQYCFSTGSIWEDTFPIRGKDGAFNWFLSRALPLRDARGHITHWLGTHTDITAQVNAEEALRELNESLELRVAERT
RELETANKLLQAEIAERAMAEEALRHAQKMDAIGQLTGGIAHDFNNVLSGVIGALDMIRLRVAAGRIGEVARYLDAAASS
ANRAAALTRRLLTFARRQSLNVTVVDVNCMVRSMEELLRGTVGAHAHLEIELEEGLSAVRTDEHQLENALLNLVINARDA
VPVGGRLCVRSRSLTLAAQKEGLLPGDYIQLSVEDNGCGIAQDVIDQVFDPFFTTKPVGQGTGLGLSMVYGFTRQSGGHV
HIESTEGQGTRVHLQLPCGKAAVA
>Mature_423_residues
PLHSAEQDREVAQYIDALRESERQFRTLADNMSQLAWTASPRGQVHWYNERWYAYTGASLEAMTALGWRSVLHPEHRERV
MARLQYCFSTGSIWEDTFPIRGKDGAFNWFLSRALPLRDARGHITHWLGTHTDITAQVNAEEALRELNESLELRVAERTR
ELETANKLLQAEIAERAMAEEALRHAQKMDAIGQLTGGIAHDFNNVLSGVIGALDMIRLRVAAGRIGEVARYLDAAASSA
NRAAALTRRLLTFARRQSLNVTVVDVNCMVRSMEELLRGTVGAHAHLEIELEEGLSAVRTDEHQLENALLNLVINARDAV
PVGGRLCVRSRSLTLAAQKEGLLPGDYIQLSVEDNGCGIAQDVIDQVFDPFFTTKPVGQGTGLGLSMVYGFTRQSGGHVH
IESTEGQGTRVHLQLPCGKAAVA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=30.0411522633745, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=27.6, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=28.3185840707965, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=305, Percent_Identity=22.2950819672131, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=29.3172690763052, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=256, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46896; Mature: 46764

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLHSAEQDREVAQYIDALRESERQFRTLADNMSQLAWTASPRGQVHWYNERWYAYTGAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCEEEEEECCC
LEAMTALGWRSVLHPEHRERVMARLQYCFSTGSIWEDTFPIRGKDGAFNWFLSRALPLRD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
ARGHITHWLGTHTDITAQVNAEEALRELNESLELRVAERTRELETANKLLQAEIAERAMA
CCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEALRHAQKMDAIGQLTGGIAHDFNNVLSGVIGALDMIRLRVAAGRIGEVARYLDAAASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANRAAALTRRLLTFARRQSLNVTVVDVNCMVRSMEELLRGTVGAHAHLEIELEEGLSAVR
CHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHH
TDEHQLENALLNLVINARDAVPVGGRLCVRSRSLTLAAQKEGLLPGDYIQLSVEDNGCGI
CHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCEEEEEECCCCCCH
AQDVIDQVFDPFFTTKPVGQGTGLGLSMVYGFTRQSGGHVHIESTEGQGTRVHLQLPCGK
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCC
AAVA
CCCC
>Mature Secondary Structure 
PLHSAEQDREVAQYIDALRESERQFRTLADNMSQLAWTASPRGQVHWYNERWYAYTGAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCEEEEEECCC
LEAMTALGWRSVLHPEHRERVMARLQYCFSTGSIWEDTFPIRGKDGAFNWFLSRALPLRD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
ARGHITHWLGTHTDITAQVNAEEALRELNESLELRVAERTRELETANKLLQAEIAERAMA
CCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEALRHAQKMDAIGQLTGGIAHDFNNVLSGVIGALDMIRLRVAAGRIGEVARYLDAAASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANRAAALTRRLLTFARRQSLNVTVVDVNCMVRSMEELLRGTVGAHAHLEIELEEGLSAVR
CHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHH
TDEHQLENALLNLVINARDAVPVGGRLCVRSRSLTLAAQKEGLLPGDYIQLSVEDNGCGI
CHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCEEEEEECCCCCCH
AQDVIDQVFDPFFTTKPVGQGTGLGLSMVYGFTRQSGGHVHIESTEGQGTRVHLQLPCGK
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCC
AAVA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA