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The map label for this gene is ppiC [H]

Identifier: 66046138

GI number: 66046138

Start: 3487120

End: 3487395

Strand: Direct

Name: ppiC [H]

Synonym: Psyr_2907

Alternate gene names: 66046138

Gene position: 3487120-3487395 (Clockwise)

Preceding gene: 66046136

Following gene: 66046144

Centisome position: 57.23

GC content: 56.88

Gene sequence:

>276_bases
ATGAAAGCCCAAGCCCGCCATATTCTGGTGAAGACCGCCGAAGAGGCAGAACAGCTCAAGCTGCGCATTGCCAAGGGTGA
GGCGTTTGACGTGCTGGCTAAAAAGCATTCTAGCTGCCCGTCCGGCAAACGTGGCGGCGATCTGGGCGAAGTCAGGCCTG
GGCAAATGGTCGGCGCCATCGATCAGGTGATCTTCAAAAAGCCGCTGCGCATCGTGCATGGGCCAATCAAGAGCAAATTC
GGCTATCACCTGGTGCAGGTGTTCTATCGCGACTGA

Upstream 100 bases:

>100_bases
TAAAGAGACCACGACCGTCAGGACAGCACGTGTGACGCGCGGGCGTCGCTCAGCAAGAGCAGGCATAATGGCAGCCTTTT
GCAGCAGGTGATATTGCGAC

Downstream 100 bases:

>100_bases
CGCACAGGTCAAAAGCTGAAAAACCCCGAACCGAGCGCGGTTCGAGGTTTTTCGGGCATCGGCCAGCGCGCTGATCAGTT
CGGCGAAATGGCGCCGTCTA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MKAQARHILVKTAEEAEQLKLRIAKGEAFDVLAKKHSSCPSGKRGGDLGEVRPGQMVGAIDQVIFKKPLRIVHGPIKSKF
GYHLVQVFYRD

Sequences:

>Translated_91_residues
MKAQARHILVKTAEEAEQLKLRIAKGEAFDVLAKKHSSCPSGKRGGDLGEVRPGQMVGAIDQVIFKKPLRIVHGPIKSKF
GYHLVQVFYRD
>Mature_91_residues
MKAQARHILVKTAEEAEQLKLRIAKGEAFDVLAKKHSSCPSGKRGGDLGEVRPGQMVGAIDQVIFKKPLRIVHGPIKSKF
GYHLVQVFYRD

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=89, Percent_Identity=55.0561797752809, Blast_Score=97, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 10125; Mature: 10125

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQARHILVKTAEEAEQLKLRIAKGEAFDVLAKKHSSCPSGKRGGDLGEVRPGQMVGAI
CCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
DQVIFKKPLRIVHGPIKSKFGYHLVQVFYRD
HHHHHHHHHHHHHCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MKAQARHILVKTAEEAEQLKLRIAKGEAFDVLAKKHSSCPSGKRGGDLGEVRPGQMVGAI
CCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
DQVIFKKPLRIVHGPIKSKFGYHLVQVFYRD
HHHHHHHHHHHHHCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]