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The map label for this gene is pgsA [H]

Identifier: 66046126

GI number: 66046126

Start: 3473892

End: 3474452

Strand: Reverse

Name: pgsA [H]

Synonym: Psyr_2895

Alternate gene names: 66046126

Gene position: 3474452-3473892 (Counterclockwise)

Preceding gene: 66046127

Following gene: 66046124

Centisome position: 57.02

GC content: 57.58

Gene sequence:

>561_bases
ATGAATATCCCTAATCTGATCACCGTACTACGCGTTTTACTGATTCCGATCTTCATTTTGTTGTTCTACATGCCTTATCA
CTGGAGCTACATGGCGGCCAGTGCAGTCTTTGCGTTCGCTGCGGCGACCGACTGGCTCGACGGGTATCTGGCCCGCCGTC
TTGAACAAAGCACGCCCTTTGGCGCCTTTCTCGATCCGGTAGCCGACAAGCTGATGGTGGCCGTGGCATTGGTGCTGCTG
GTTCAGGCGCATGCCAATCTATGGCTGACGCTGCCCGCAGCGGTGATCATCGGCCGTGAAATCGTAATCTCTGCACTCCG
CGAATGGATGGCGGAAATCGGCGCGCGTGCGCAGGTTGCCGTTTCCAACATGGGTAAATGGAAGACGGCGGCGCAGATGC
TCGCGCTGGTCATTCTGCTCGGCAACCCGCCGGCCATCACCCTGTGGGTGATTCTCGGCTATGCGCTGCTGCTCATTGCT
GCGGGGCTGACCCTGTGGTCCATGGTGCAATACCTGAGAGCCGCGTGGCCGCACCTCAGGACCACTTCAGAAAAAAAATA
A

Upstream 100 bases:

>100_bases
TAGCAAAAGCACCCGGAATCAGCAAAAAGCTGGCAGAGTCGATTTATGCAAACCTGCACAGCGAGTAGAATGCTCGTTCA
CCTCGTAGCCAGTTGTGCCG

Downstream 100 bases:

>100_bases
GTTTTTGAATCAAAGGCTTGACGCCGCTATCTGAACCGCTAGAATAGCGCCCGTCATCAAGACAATGCGGGAATAGCTCA
GTTGGTAGAGCACGACCTTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVAVSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIA
AGLTLWSMVQYLRAAWPHLRTTSEKK

Sequences:

>Translated_186_residues
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVAVSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIA
AGLTLWSMVQYLRAAWPHLRTTSEKK
>Mature_186_residues
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVAVSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIA
AGLTLWSMVQYLRAAWPHLRTTSEKK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=60.2272727272727, Blast_Score=201, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320059, Length=157, Percent_Identity=33.7579617834395, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20600; Mature: 20600

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAFLDPVADKLMVAVALVLLVQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIAAGLTLWSMVQYLRAAWPHLR
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
TTSEKK
CCCCCC
>Mature Secondary Structure
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAFLDPVADKLMVAVALVLLVQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIAAGLTLWSMVQYLRAAWPHLR
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
TTSEKK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075420 [H]