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The map label for this gene is baeS [H]

Identifier: 66046100

GI number: 66046100

Start: 3441397

End: 3442788

Strand: Direct

Name: baeS [H]

Synonym: Psyr_2867

Alternate gene names: 66046100

Gene position: 3441397-3442788 (Clockwise)

Preceding gene: 66046095

Following gene: 66046101

Centisome position: 56.47

GC content: 63.0

Gene sequence:

>1392_bases
ATGAAATCGAGCATCTCCACCAAACTGTTTGTCGCGGTACTGGCCAGCGTGCTGTCAGTGATCCTGATCATGGGCCTGAC
CGCGAACTGGAGTTTTGCCCGCGGCTTTCTGGGCTACCTCAACGAACAGGCCATGCAACGCATGTCGCCGGTCCTGCCGC
GGTTGGCCGCTGCCTATGCACGCGAAGGCAGTTGGGAATTCATGCGTGACAACAAGGATCGCTGGTTCGAAGTGATGCGC
CCGGAACCGGCACAGGATTTCGCCATCCCCGGACTGGCGACACCGCCTACTTCCGACTTGACCGGCGCGGTGTTCCGGAT
CGCGCTGCTGGATGCGCAGAAGAACCTGGTGATGGGATTCCCAGGGGTCCATGACGATGAATTCATGCGCCCGGTGGAAG
TCGACGGCAACGTCGTTGGCTGGATGGCGGTCACGCCCTTTCAAAGTGTCAGCGAAGCCGGTGGCGAGCGCTTTCAGCAG
TATCAGTTGCGCGCCAGCCTGGCGATGGGTGTGCTGTCACTGCTGCTGGCGGTGCTGATTGCCTGGTGGATCGCGCGCAC
CCTGCTCGACCCGGTCAAGCGGGTGGCCGCAGCAACCCATCGCCTCGCCGCAGGTGAATACGCCAGCCGCGTGGCGGTGT
CCTCCAACGACGAGGTGGGTCAACTGGCGCGCGACTTCAACCAGCTGGCGTACACCCTGGAACGCAATGAGAAGATGCGC
CGCGAATTCATGGCCGATGTGTCCCATGAGCTGCGCACCCCGCTGTCGGTCTTGCGTGGCGAACTGGAAGCCATCGAGGA
TGGCGTGCGCACACTGGATCAGGCATCGATGAAGTCCCTGCAGGGCGAAGTCGGCATGCTCAGCAAGCTGGTGGATGATC
TGTATGAGCTGTCCCTGGCGGATGTGGGCGCCCTGACCTACCGCAAGGTCGACTGTGACCTGGCGGAGCTGCTGACGAAT
ATCACTGACATGTTCGAAGAGCGTTGCGCAGCCCGTCAGTTGCATTTGCAGTTGGAGCTTGCTGGCGGAGCTCTGCCGGT
GCATGCAGACCCAGGGCGCCTGCAGCAATTGATCGGCAACCTTCTGGAAAACTCGGTGCGCTACACCGATGCCGGGGGGA
CAGTGCATGTGCGTGCCGCTCTGCAGGGCGATGAGGTGCGCGTCGATGTGATGGATTCCGGACCCGGCGTCGACCCGCAG
CAATTGCCCAGACTGTTCGAACGCTTCTATCGCGGTGAAACCTCGCGTAACCGCGCCAGCGGCGGTGCGGGTCTGGGGTT
GGCGATCTGTCACAGCATCGCCCTCGCCCACGGCGGCACCCTGAGCGCCGACCACTCGCCCACAGGCGGCCTCTGGCTGA
CCCTGTGCCTGCCAGGACACCTGCGCCCATGA

Upstream 100 bases:

>100_bases
AGGCAAATGTGCAGGAAAATTGAAGATTGCCGCGTTGACTTGAAACTTGCTGTCACGAAGGCCTAAATGGACGCCGTCTT
CACGTAAAACCCGGGCCTTC

Downstream 100 bases:

>100_bases
CCGCTGCCAGCCTCGACACACCGATTCTCATTGTCGAAGATGAGCCCAAGCTGGCGTCGCTGATGCGCGACTACCTGATC
GCGGCCGGCTATTCGACACA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKSSISTKLFVAVLASVLSVILIMGLTANWSFARGFLGYLNEQAMQRMSPVLPRLAAAYAREGSWEFMRDNKDRWFEVMR
PEPAQDFAIPGLATPPTSDLTGAVFRIALLDAQKNLVMGFPGVHDDEFMRPVEVDGNVVGWMAVTPFQSVSEAGGERFQQ
YQLRASLAMGVLSLLLAVLIAWWIARTLLDPVKRVAAATHRLAAGEYASRVAVSSNDEVGQLARDFNQLAYTLERNEKMR
REFMADVSHELRTPLSVLRGELEAIEDGVRTLDQASMKSLQGEVGMLSKLVDDLYELSLADVGALTYRKVDCDLAELLTN
ITDMFEERCAARQLHLQLELAGGALPVHADPGRLQQLIGNLLENSVRYTDAGGTVHVRAALQGDEVRVDVMDSGPGVDPQ
QLPRLFERFYRGETSRNRASGGAGLGLAICHSIALAHGGTLSADHSPTGGLWLTLCLPGHLRP

Sequences:

>Translated_463_residues
MKSSISTKLFVAVLASVLSVILIMGLTANWSFARGFLGYLNEQAMQRMSPVLPRLAAAYAREGSWEFMRDNKDRWFEVMR
PEPAQDFAIPGLATPPTSDLTGAVFRIALLDAQKNLVMGFPGVHDDEFMRPVEVDGNVVGWMAVTPFQSVSEAGGERFQQ
YQLRASLAMGVLSLLLAVLIAWWIARTLLDPVKRVAAATHRLAAGEYASRVAVSSNDEVGQLARDFNQLAYTLERNEKMR
REFMADVSHELRTPLSVLRGELEAIEDGVRTLDQASMKSLQGEVGMLSKLVDDLYELSLADVGALTYRKVDCDLAELLTN
ITDMFEERCAARQLHLQLELAGGALPVHADPGRLQQLIGNLLENSVRYTDAGGTVHVRAALQGDEVRVDVMDSGPGVDPQ
QLPRLFERFYRGETSRNRASGGAGLGLAICHSIALAHGGTLSADHSPTGGLWLTLCLPGHLRP
>Mature_463_residues
MKSSISTKLFVAVLASVLSVILIMGLTANWSFARGFLGYLNEQAMQRMSPVLPRLAAAYAREGSWEFMRDNKDRWFEVMR
PEPAQDFAIPGLATPPTSDLTGAVFRIALLDAQKNLVMGFPGVHDDEFMRPVEVDGNVVGWMAVTPFQSVSEAGGERFQQ
YQLRASLAMGVLSLLLAVLIAWWIARTLLDPVKRVAAATHRLAAGEYASRVAVSSNDEVGQLARDFNQLAYTLERNEKMR
REFMADVSHELRTPLSVLRGELEAIEDGVRTLDQASMKSLQGEVGMLSKLVDDLYELSLADVGALTYRKVDCDLAELLTN
ITDMFEERCAARQLHLQLELAGGALPVHADPGRLQQLIGNLLENSVRYTDAGGTVHVRAALQGDEVRVDVMDSGPGVDPQ
QLPRLFERFYRGETSRNRASGGAGLGLAICHSIALAHGGTLSADHSPTGGLWLTLCLPGHLRP

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=459, Percent_Identity=45.0980392156863, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=30.3030303030303, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786912, Length=286, Percent_Identity=29.7202797202797, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=31.6666666666667, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=29.5918367346939, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=30.8880308880309, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=30.6122448979592, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788279, Length=323, Percent_Identity=24.7678018575851, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789149, Length=371, Percent_Identity=24.5283018867925, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081816, Length=341, Percent_Identity=26.9794721407625, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=26.3513513513513, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082128, Length=277, Percent_Identity=29.2418772563177, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=29.4372294372294, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=26.6393442622951, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789403, Length=310, Percent_Identity=28.3870967741935, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=319, Percent_Identity=24.7648902821317, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=27.1551724137931, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=27.4305555555556, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=25.5707762557078, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=24.3150684931507, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50670; Mature: 50670

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSISTKLFVAVLASVLSVILIMGLTANWSFARGFLGYLNEQAMQRMSPVLPRLAAAYA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGSWEFMRDNKDRWFEVMRPEPAQDFAIPGLATPPTSDLTGAVFRIALLDAQKNLVMGF
CCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PGVHDDEFMRPVEVDGNVVGWMAVTPFQSVSEAGGERFQQYQLRASLAMGVLSLLLAVLI
CCCCCHHHCCCEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWWIARTLLDPVKRVAAATHRLAAGEYASRVAVSSNDEVGQLARDFNQLAYTLERNEKMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
REFMADVSHELRTPLSVLRGELEAIEDGVRTLDQASMKSLQGEVGMLSKLVDDLYELSLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DVGALTYRKVDCDLAELLTNITDMFEERCAARQLHLQLELAGGALPVHADPGRLQQLIGN
HHCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCHHHHHHHHHH
LLENSVRYTDAGGTVHVRAALQGDEVRVDVMDSGPGVDPQQLPRLFERFYRGETSRNRAS
HHHCCCEEECCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GGAGLGLAICHSIALAHGGTLSADHSPTGGLWLTLCLPGHLRP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKSSISTKLFVAVLASVLSVILIMGLTANWSFARGFLGYLNEQAMQRMSPVLPRLAAAYA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGSWEFMRDNKDRWFEVMRPEPAQDFAIPGLATPPTSDLTGAVFRIALLDAQKNLVMGF
CCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PGVHDDEFMRPVEVDGNVVGWMAVTPFQSVSEAGGERFQQYQLRASLAMGVLSLLLAVLI
CCCCCHHHCCCEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWWIARTLLDPVKRVAAATHRLAAGEYASRVAVSSNDEVGQLARDFNQLAYTLERNEKMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
REFMADVSHELRTPLSVLRGELEAIEDGVRTLDQASMKSLQGEVGMLSKLVDDLYELSLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DVGALTYRKVDCDLAELLTNITDMFEERCAARQLHLQLELAGGALPVHADPGRLQQLIGN
HHCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCHHHHHHHHHH
LLENSVRYTDAGGTVHVRAALQGDEVRVDVMDSGPGVDPQQLPRLFERFYRGETSRNRAS
HHHCCCEEECCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GGAGLGLAICHSIALAHGGTLSADHSPTGGLWLTLCLPGHLRP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]