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The map label for this gene is fadD [C]

Identifier: 66045962

GI number: 66045962

Start: 3307967

End: 3309868

Strand: Reverse

Name: fadD [C]

Synonym: Psyr_2726

Alternate gene names: 66045962

Gene position: 3309868-3307967 (Counterclockwise)

Preceding gene: 66045963

Following gene: 66045961

Centisome position: 54.32

GC content: 62.88

Gene sequence:

>1902_bases
ATGGAGAGAACGCACGTGAGTTCCGATATCAGATCGTCAACGCTGCAGAGTGAAGATAATCCACCGCGCTATCGTCAGGT
CTCCATCGGCCACCCGCCCATCGAGGTGCGGGAAGAGCAGGGCGTTCTGCACATGCGGGCCCTGGAACCCCTGGCCCGGT
TACCCGACCGGCTGCTCGACCGACTGGTGCATTGGGCGCAGTTGCGTCCGCAACAGACCTTCATTGCCGCTCGCGACAGC
CGTGGCGGCTGGCGCAAGGTCAGTTATGCCGAGATGCTGACTGACGTGCGCGCTATCGCACAGAGCCTGCTGGCGTACGG
ACTTTCCGCCGATCGGCCGCTGGCGTTGCTGTCAGGTAATGACATCGAGCACTTGCAGCTCGCTCTGGGTGCCATGTACG
CCGGCATTCCCTACTGCCCGGTCTCACCGGCATATTCGGTCATGTCTCAGGATTTCGCCAAGTTACGACACGTCTGCGAC
GTGCTGCGGCCAGGACTGGTATTTGTCAGTGATGCCGCGCCGTTTCAGCGAGCCATCGATGCGGTCATTGCGGCCGACAC
GCCGGTCATCACTGTACGCGGACAGCTCAATGGCAGGCCTGCGCTGAGCTTCGCCAGCCTGCTCGAAGAACCGGGTGGCA
GCGAGGCGGATGCCGCTTTCCTGGCCAGCGGCCCCAACACCATCGCCAAGTTTCTGTTCACCTCGGGCTCGACCAAACTG
CCCAAGGCGGTGGTGACCACCCAGCGCATGCTGTGTGCCAATCAACAGATGCTCTTGCAGACATTTCCGGTGTTCGGCGA
AGAACCGCCCGTGCTGGTCGACTGGCTGCCCTGGAACCACACCTTCGGCGGCAGTCATAATCTCGGCATCGTGCTGTACA
ACGGTGGCACGTTCTATCTGGACAACGGCAAGCCAACCGTTCAAGGCTTCGCCGAGACCCTGCGCAACCTCAAGGAAATT
TCGCCTACCGCTTACCTGACTGTGCCCAAGGGCTGGGAGGAGCTGGTCAACGCACTGGAGCAGGACGCCGAGCTGCGCGA
GCGATTCTTCTCGCGTATCAAGCTGTTCTTCTTCGCCGCTGCCGGCCTGTCGCAAAGCATCTGGGATCGCCTTGACCGGG
TGGCCGAGCAGCATTGCGGCGAGCGGATTCGCATGATGGCCGGACTGGGCATGACCGAGGCTGCGCCGTCCTGCACCTTC
ACCACCGGGCCCTTGTCGATGGCCGGTTACATCGGCCTGCCCGCACCGGGATGCGAAGTGTGTCTGGTGCCTGTGGATGG
CAAGCTCGAAGGACGTTTTCGTGGTCCGCACATCATGCCGGGCTATTGGCGCTCGCCGCAGCAGACTGCCGAAGTGTTCG
ACGAGAACGGCTTCTATTGCTCCGGCGATGCGATCAAGCTTGCCGATCCTGCGGCACCCGAGCTGGGCCTGATGTTCGAC
GGGCGTCTGGCCGAGGATTTCAAGCTGTCGTCGGGCGTGTTCGTCAGTGTCGGGCCGATGCGCAATCGGGCGGTGCTGGA
AGGCTCGCCGTACGTGCAGGATGTGGTCATCACCGCGCCTGACCGCGAATGCCTCGGGGCGCTGGTGTTTCCCAGAGTGC
ACGAGTGTCGGCAACTGGCCGGGCTGGATGCACAGGCCACGGATGCACAGGTACTGGCCAGTGCGCCGGTACGTGAGTGG
TTCGCCGGCTGGCTGGCGCGCCTGAATCAGGGCGCGAACGGCAACGCCAGCAGGCTGGAGTGGATCGTGCTGCTTGATCA
GCCCGCGTCCATTGATCGCGGCGAAATTACCGACAAGGGGTCGATCAACCAGCGCGCTGTTCTGCAGTGGCGCGCAGACA
AGGTCGAAGCGCTGTACCGTGATCAGGATCCGGACAAGCTCCGTGCCGAGCCCAAGGCATGA

Upstream 100 bases:

>100_bases
GAGCCTCCGGTGAGTCAGGCACAACAATAACAAGGCTGCAGCCTGGTGCTGCAACGCTCGGCCCGAACTGCTGCATGGCG
TTTGGCGCCTGCGTACCTTG

Downstream 100 bases:

>100_bases
GTGGCAGCGGGCAGTATTCGGCATTCAGTGACGTGGCCATCGTCGATGCGGTGCGCACGCCCTGGGTGGATCTGGGCGGT
GCTCTGGCACCTGTCTCGCC

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MERTHVSSDIRSSTLQSEDNPPRYRQVSIGHPPIEVREEQGVLHMRALEPLARLPDRLLDRLVHWAQLRPQQTFIAARDS
RGGWRKVSYAEMLTDVRAIAQSLLAYGLSADRPLALLSGNDIEHLQLALGAMYAGIPYCPVSPAYSVMSQDFAKLRHVCD
VLRPGLVFVSDAAPFQRAIDAVIAADTPVITVRGQLNGRPALSFASLLEEPGGSEADAAFLASGPNTIAKFLFTSGSTKL
PKAVVTTQRMLCANQQMLLQTFPVFGEEPPVLVDWLPWNHTFGGSHNLGIVLYNGGTFYLDNGKPTVQGFAETLRNLKEI
SPTAYLTVPKGWEELVNALEQDAELRERFFSRIKLFFFAAAGLSQSIWDRLDRVAEQHCGERIRMMAGLGMTEAAPSCTF
TTGPLSMAGYIGLPAPGCEVCLVPVDGKLEGRFRGPHIMPGYWRSPQQTAEVFDENGFYCSGDAIKLADPAAPELGLMFD
GRLAEDFKLSSGVFVSVGPMRNRAVLEGSPYVQDVVITAPDRECLGALVFPRVHECRQLAGLDAQATDAQVLASAPVREW
FAGWLARLNQGANGNASRLEWIVLLDQPASIDRGEITDKGSINQRAVLQWRADKVEALYRDQDPDKLRAEPKA

Sequences:

>Translated_633_residues
MERTHVSSDIRSSTLQSEDNPPRYRQVSIGHPPIEVREEQGVLHMRALEPLARLPDRLLDRLVHWAQLRPQQTFIAARDS
RGGWRKVSYAEMLTDVRAIAQSLLAYGLSADRPLALLSGNDIEHLQLALGAMYAGIPYCPVSPAYSVMSQDFAKLRHVCD
VLRPGLVFVSDAAPFQRAIDAVIAADTPVITVRGQLNGRPALSFASLLEEPGGSEADAAFLASGPNTIAKFLFTSGSTKL
PKAVVTTQRMLCANQQMLLQTFPVFGEEPPVLVDWLPWNHTFGGSHNLGIVLYNGGTFYLDNGKPTVQGFAETLRNLKEI
SPTAYLTVPKGWEELVNALEQDAELRERFFSRIKLFFFAAAGLSQSIWDRLDRVAEQHCGERIRMMAGLGMTEAAPSCTF
TTGPLSMAGYIGLPAPGCEVCLVPVDGKLEGRFRGPHIMPGYWRSPQQTAEVFDENGFYCSGDAIKLADPAAPELGLMFD
GRLAEDFKLSSGVFVSVGPMRNRAVLEGSPYVQDVVITAPDRECLGALVFPRVHECRQLAGLDAQATDAQVLASAPVREW
FAGWLARLNQGANGNASRLEWIVLLDQPASIDRGEITDKGSINQRAVLQWRADKVEALYRDQDPDKLRAEPKA
>Mature_633_residues
MERTHVSSDIRSSTLQSEDNPPRYRQVSIGHPPIEVREEQGVLHMRALEPLARLPDRLLDRLVHWAQLRPQQTFIAARDS
RGGWRKVSYAEMLTDVRAIAQSLLAYGLSADRPLALLSGNDIEHLQLALGAMYAGIPYCPVSPAYSVMSQDFAKLRHVCD
VLRPGLVFVSDAAPFQRAIDAVIAADTPVITVRGQLNGRPALSFASLLEEPGGSEADAAFLASGPNTIAKFLFTSGSTKL
PKAVVTTQRMLCANQQMLLQTFPVFGEEPPVLVDWLPWNHTFGGSHNLGIVLYNGGTFYLDNGKPTVQGFAETLRNLKEI
SPTAYLTVPKGWEELVNALEQDAELRERFFSRIKLFFFAAAGLSQSIWDRLDRVAEQHCGERIRMMAGLGMTEAAPSCTF
TTGPLSMAGYIGLPAPGCEVCLVPVDGKLEGRFRGPHIMPGYWRSPQQTAEVFDENGFYCSGDAIKLADPAAPELGLMFD
GRLAEDFKLSSGVFVSVGPMRNRAVLEGSPYVQDVVITAPDRECLGALVFPRVHECRQLAGLDAQATDAQVLASAPVREW
FAGWLARLNQGANGNASRLEWIVLLDQPASIDRGEITDKGSINQRAVLQWRADKVEALYRDQDPDKLRAEPKA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI57165412, Length=391, Percent_Identity=24.8081841432225, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI57165410, Length=394, Percent_Identity=24.6192893401015, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI40807491, Length=438, Percent_Identity=22.1461187214612, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1788107, Length=300, Percent_Identity=27.3333333333333, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17556552, Length=348, Percent_Identity=26.7241379310345, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=486, Percent_Identity=24.2798353909465, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=462, Percent_Identity=25.1082251082251, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564090, Length=455, Percent_Identity=24.1758241758242, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17510401, Length=197, Percent_Identity=30.9644670050761, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 69511; Mature: 69511

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTHVSSDIRSSTLQSEDNPPRYRQVSIGHPPIEVREEQGVLHMRALEPLARLPDRLLD
CCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHH
RLVHWAQLRPQQTFIAARDSRGGWRKVSYAEMLTDVRAIAQSLLAYGLSADRPLALLSGN
HHHHHHHCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
DIEHLQLALGAMYAGIPYCPVSPAYSVMSQDFAKLRHVCDVLRPGLVFVSDAAPFQRAID
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
AVIAADTPVITVRGQLNGRPALSFASLLEEPGGSEADAAFLASGPNTIAKFLFTSGSTKL
HHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCC
PKAVVTTQRMLCANQQMLLQTFPVFGEEPPVLVDWLPWNHTFGGSHNLGIVLYNGGTFYL
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEE
DNGKPTVQGFAETLRNLKEISPTAYLTVPKGWEELVNALEQDAELRERFFSRIKLFFFAA
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLSQSIWDRLDRVAEQHCGERIRMMAGLGMTEAAPSCTFTTGPLSMAGYIGLPAPGCEV
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCE
CLVPVDGKLEGRFRGPHIMPGYWRSPQQTAEVFDENGFYCSGDAIKLADPAAPELGLMFD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCEEEECCCCCCCCCEEEC
GRLAEDFKLSSGVFVSVGPMRNRAVLEGSPYVQDVVITAPDRECLGALVFPRVHECRQLA
CCCCCCEECCCCEEEEECCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GLDAQATDAQVLASAPVREWFAGWLARLNQGANGNASRLEWIVLLDQPASIDRGEITDKG
CCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
SINQRAVLQWRADKVEALYRDQDPDKLRAEPKA
CCCCHHHEEEHHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MERTHVSSDIRSSTLQSEDNPPRYRQVSIGHPPIEVREEQGVLHMRALEPLARLPDRLLD
CCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHH
RLVHWAQLRPQQTFIAARDSRGGWRKVSYAEMLTDVRAIAQSLLAYGLSADRPLALLSGN
HHHHHHHCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
DIEHLQLALGAMYAGIPYCPVSPAYSVMSQDFAKLRHVCDVLRPGLVFVSDAAPFQRAID
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
AVIAADTPVITVRGQLNGRPALSFASLLEEPGGSEADAAFLASGPNTIAKFLFTSGSTKL
HHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCC
PKAVVTTQRMLCANQQMLLQTFPVFGEEPPVLVDWLPWNHTFGGSHNLGIVLYNGGTFYL
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEE
DNGKPTVQGFAETLRNLKEISPTAYLTVPKGWEELVNALEQDAELRERFFSRIKLFFFAA
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLSQSIWDRLDRVAEQHCGERIRMMAGLGMTEAAPSCTFTTGPLSMAGYIGLPAPGCEV
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCE
CLVPVDGKLEGRFRGPHIMPGYWRSPQQTAEVFDENGFYCSGDAIKLADPAAPELGLMFD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCEEEECCCCCCCCCEEEC
GRLAEDFKLSSGVFVSVGPMRNRAVLEGSPYVQDVVITAPDRECLGALVFPRVHECRQLA
CCCCCCEECCCCEEEEECCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
GLDAQATDAQVLASAPVREWFAGWLARLNQGANGNASRLEWIVLLDQPASIDRGEITDKG
CCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
SINQRAVLQWRADKVEALYRDQDPDKLRAEPKA
CCCCHHHEEEHHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]