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The map label for this gene is argD [H]

Identifier: 66045787

GI number: 66045787

Start: 2964735

End: 2965991

Strand: Direct

Name: argD [H]

Synonym: Psyr_2551

Alternate gene names: 66045787

Gene position: 2964735-2965991 (Clockwise)

Preceding gene: 66045786

Following gene: 66045788

Centisome position: 48.65

GC content: 64.2

Gene sequence:

>1257_bases
ATGAACAGTCATGTCATGAGTGCGCCGGCGAGCGTGCCTGCGCGCAAATCCTCATTCGTCGAACGCTACGGTGCGGTGTT
TGGCCGTGAGCAAGGCCTTATGTTGCGCATGGCCGGGCTGACCGCAGCCGAACACTCGGCCGAGGGGTCGTGGATAACCG
ATGACACCGGCCGCCGCTGGCTGGACTTCGGTTCCTTCGGGCTGCACCTGCTGGGCCACCGGCACCCTCAGGTCGTGGCT
GCGCTGACGCGACAGGTGACATCACTGGGCCTTTCCAGCCGGATCCTGGCCAACGAATCCAGCCTGAGCGCCGCCGAGCG
GCTTGTGACGTGTGTCGGCCGTCCGGGCAACGGCGTGCTTTACGGCAACAGCGGTTCGGAGGTCATCGAAGCAGCCCTCA
AGCTGGTGCGCATGCAGACTGGCCGGCGGCGCATCATCGCCTTGACCCACGCCTACCATGGCCGGACCAGTGGCGCGCTT
GCGGTCAGCTATGGCTATCGCGGGCACGCCGCGCTGATGCACGCCGAAGATGTCGTGTTCATTGCTGCCGGTGATCTTGC
CGCTGCACGCCAGGCACTGGCAGAGGGCGATATTGCCGCAGTGATCGCCGAGCCGGTTCAGGGCGAGGGCGGAATCAGGC
CGGTCGACCTGGATTTTCTGGGCGAACTTGCAGGGCTGTGTCGCGAACATGGCGCGTTCATGATTCATGACGAGATTCAA
TCCGGCCTGGGGCGCAGCGGATCGCTGATCTGCGGCGCGCCCGCCGACATCGTCGTGTTCGGCAAAACCCTGGGCGGTGG
TGTGTTTCCAGTGGCCGCCGCCATTTATGACAGCAGCCGCTTCGGAGCACCGGCGCGTGATCCGGTCGTGCATGCCTCGT
CCTACGCTGGCAGCGCGCTGGCGGGAGCCGTGGTCAACGCTGTGCTCGACGTGGTCAGCGATCCCGCATTCTGTCAGCGC
GTCAACCAGCTGGGGCAGGTGGCCATGAGCATCCTGCGTGAGCGTTTACAGGACTGTCCTGCCGTGGCTGAAGTGCGTGG
CAGCGGCCTGATGATCGGGGTGGAATTCACCTCCAGCAACTATGTGGCGCAGACCCTGATCGAAGCCGCGCAGCGCAATG
TGCTGCTGGCGTTCTGCCTGAGCGCAACCTCCGTGCTGCGGGTGTATCCCGACGCGACCATCTCCCGAGACCACCTCGAA
CAAGGCATCAACAGTTTCTGTGATGCCGTCGATGCGGCTTATCGCTCCATTCAATGA

Upstream 100 bases:

>100_bases
GCACTCAGGGTCAGGTGTTGCGAACCCTGCGCGACTGGGACCGCTCCTGCCGCCTGGCAGGTGGTGATGCTGCCTTTCTG
GCACCTTTGATGAGGTCTCT

Downstream 100 bases:

>100_bases
CGGAGAATTCCTATGCCTGATGTATCAACCAGTGTTCTTCTCGGTGACTTCGAGCCTGGCGAGGTCTGGCCGATTCTCTC
GGACTTCGCTCGCTATCCCG

Product: aminotransferase class-III

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNSHVMSAPASVPARKSSFVERYGAVFGREQGLMLRMAGLTAAEHSAEGSWITDDTGRRWLDFGSFGLHLLGHRHPQVVA
ALTRQVTSLGLSSRILANESSLSAAERLVTCVGRPGNGVLYGNSGSEVIEAALKLVRMQTGRRRIIALTHAYHGRTSGAL
AVSYGYRGHAALMHAEDVVFIAAGDLAAARQALAEGDIAAVIAEPVQGEGGIRPVDLDFLGELAGLCREHGAFMIHDEIQ
SGLGRSGSLICGAPADIVVFGKTLGGGVFPVAAAIYDSSRFGAPARDPVVHASSYAGSALAGAVVNAVLDVVSDPAFCQR
VNQLGQVAMSILRERLQDCPAVAEVRGSGLMIGVEFTSSNYVAQTLIEAAQRNVLLAFCLSATSVLRVYPDATISRDHLE
QGINSFCDAVDAAYRSIQ

Sequences:

>Translated_418_residues
MNSHVMSAPASVPARKSSFVERYGAVFGREQGLMLRMAGLTAAEHSAEGSWITDDTGRRWLDFGSFGLHLLGHRHPQVVA
ALTRQVTSLGLSSRILANESSLSAAERLVTCVGRPGNGVLYGNSGSEVIEAALKLVRMQTGRRRIIALTHAYHGRTSGAL
AVSYGYRGHAALMHAEDVVFIAAGDLAAARQALAEGDIAAVIAEPVQGEGGIRPVDLDFLGELAGLCREHGAFMIHDEIQ
SGLGRSGSLICGAPADIVVFGKTLGGGVFPVAAAIYDSSRFGAPARDPVVHASSYAGSALAGAVVNAVLDVVSDPAFCQR
VNQLGQVAMSILRERLQDCPAVAEVRGSGLMIGVEFTSSNYVAQTLIEAAQRNVLLAFCLSATSVLRVYPDATISRDHLE
QGINSFCDAVDAAYRSIQ
>Mature_418_residues
MNSHVMSAPASVPARKSSFVERYGAVFGREQGLMLRMAGLTAAEHSAEGSWITDDTGRRWLDFGSFGLHLLGHRHPQVVA
ALTRQVTSLGLSSRILANESSLSAAERLVTCVGRPGNGVLYGNSGSEVIEAALKLVRMQTGRRRIIALTHAYHGRTSGAL
AVSYGYRGHAALMHAEDVVFIAAGDLAAARQALAEGDIAAVIAEPVQGEGGIRPVDLDFLGELAGLCREHGAFMIHDEIQ
SGLGRSGSLICGAPADIVVFGKTLGGGVFPVAAAIYDSSRFGAPARDPVVHASSYAGSALAGAVVNAVLDVVSDPAFCQR
VNQLGQVAMSILRERLQDCPAVAEVRGSGLMIGVEFTSSNYVAQTLIEAAQRNVLLAFCLSATSVLRVYPDATISRDHLE
QGINSFCDAVDAAYRSIQ

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=31.5926892950392, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI13994255, Length=366, Percent_Identity=28.4153005464481, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=31.1036789297659, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=26.7469879518072, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI24119277, Length=397, Percent_Identity=27.7078085642317, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=26.8542199488491, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=25.7831325301205, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=30.2083333333333, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=31.331592689295, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=32.8083989501312, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=31.9899244332494, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=32.089552238806, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=30.5389221556886, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786991, Length=354, Percent_Identity=28.8135593220339, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=28.6445012787724, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=408, Percent_Identity=25.4901960784314, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32564660, Length=427, Percent_Identity=26.9320843091335, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=225, Percent_Identity=32, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324432, Length=388, Percent_Identity=32.4742268041237, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=32.7586206896552, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574759, Length=405, Percent_Identity=28.3950617283951, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI161085790, Length=360, Percent_Identity=29.4444444444444, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=27.9373368146214, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356575, Length=343, Percent_Identity=28.2798833819242, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43957; Mature: 43957

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHVMSAPASVPARKSSFVERYGAVFGREQGLMLRMAGLTAAEHSAEGSWITDDTGRRW
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCEEECCCCCCE
LDFGSFGLHLLGHRHPQVVAALTRQVTSLGLSSRILANESSLSAAERLVTCVGRPGNGVL
EECCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
YGNSGSEVIEAALKLVRMQTGRRRIIALTHAYHGRTSGALAVSYGYRGHAALMHAEDVVF
ECCCCHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCEEEEEECCCCCEEEEEECCEEE
IAAGDLAAARQALAEGDIAAVIAEPVQGEGGIRPVDLDFLGELAGLCREHGAFMIHDEIQ
EEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEHHHH
SGLGRSGSLICGAPADIVVFGKTLGGGVFPVAAAIYDSSRFGAPARDPVVHASSYAGSAL
HCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHH
AGAVVNAVLDVVSDPAFCQRVNQLGQVAMSILRERLQDCPAVAEVRGSGLMIGVEFTSSN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCC
YVAQTLIEAAQRNVLLAFCLSATSVLRVYPDATISRDHLEQGINSFCDAVDAAYRSIQ
HHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSHVMSAPASVPARKSSFVERYGAVFGREQGLMLRMAGLTAAEHSAEGSWITDDTGRRW
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCEEECCCCCCE
LDFGSFGLHLLGHRHPQVVAALTRQVTSLGLSSRILANESSLSAAERLVTCVGRPGNGVL
EECCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
YGNSGSEVIEAALKLVRMQTGRRRIIALTHAYHGRTSGALAVSYGYRGHAALMHAEDVVF
ECCCCHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCEEEEEECCCCCEEEEEECCEEE
IAAGDLAAARQALAEGDIAAVIAEPVQGEGGIRPVDLDFLGELAGLCREHGAFMIHDEIQ
EEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEHHHH
SGLGRSGSLICGAPADIVVFGKTLGGGVFPVAAAIYDSSRFGAPARDPVVHASSYAGSAL
HCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHH
AGAVVNAVLDVVSDPAFCQRVNQLGQVAMSILRERLQDCPAVAEVRGSGLMIGVEFTSSN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCC
YVAQTLIEAAQRNVLLAFCLSATSVLRVYPDATISRDHLEQGINSFCDAVDAAYRSIQ
HHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]