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The map label for this gene is cobF [H]

Identifier: 66045678

GI number: 66045678

Start: 2827548

End: 2828306

Strand: Direct

Name: cobF [H]

Synonym: Psyr_2442

Alternate gene names: 66045678

Gene position: 2827548-2828306 (Clockwise)

Preceding gene: 66045669

Following gene: 66045681

Centisome position: 46.4

GC content: 61.26

Gene sequence:

>759_bases
ATGAAACAGATCCTGCTGATCGGCATGGGGGCCGGGGATCCCGAACAGATCACCCTGCAGGCCGTTGCGGCCCTGAACCT
TGCAGAGGTGATCTTCATCCTCGACAAGGGCTACGTCGACGATCAGTTGCTGAGGCTGCGCAAAGAGCTCTGTCAGCGCT
ATATCACTCATCAACGCTACCGTCTGGTGCAAGTCCAGGACCCTCGACGTGAAGATGATCCAGAGGCCTACGAGCGCGGC
ATCGAGGGGTGGCACGAACAGCGCGCGGTACTGTTCGAGCGGCTGTTGACCGATGAACTTGACGTGGATCAGGTCGGCGC
GTTTCTGGTCTGGGGCGACCCGTCGCTCTACGACAGTACGATGCGCATCCTTGACCAGGTTCTGGCGCGGGGTAAGGAGG
CTTTCGAGTATCAGGTGATACCCGGTATCACCAGCGTCCAGAGTCTGGTCGCGCGGCACCGCATCCCGCTCAATCGCATT
GGCGAGTCGATTCTTGTCACCACCGGCCGACGCATGGCGACAGCTCCGCTGCAGCACCCCGGCAACGTCGTGGTGATGCT
CGACGCGCACTGCACATTCGAGCGTTATACGGGGCAGGGGCTGGACATCTATTGGGGCGCGTACCTGGGCACGCCGGACG
AGATACTGGTGGCCGGACGGCTGGATGATGTCTGCGAGCAGATCAAGCGCCTGCGCAGTGAGGCACGCGAGCGCAAGGGG
TGGATCATGGATACCTATTTGCTGCGCAAACCGGCCTAA

Upstream 100 bases:

>100_bases
TGTTGCCAAAAGAGTAATGTGCCTGATTTTTCAGTTCAATGCCCGGTCATTGGCAAAAATCGCCTACGATCAGGCCTCTG
CACAGAGGAGGCGTTGACCG

Downstream 100 bases:

>100_bases
GCCGGTTTTTCATCCTTGTTGCGATTCTTCGCTTCGATCCACTGCGCCATGTATTTGGTGCTCTTGTGGTGATGGTGCCG
CAGCATGGCGCCGGTGAAGT

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQILLIGMGAGDPEQITLQAVAALNLAEVIFILDKGYVDDQLLRLRKELCQRYITHQRYRLVQVQDPRREDDPEAYERG
IEGWHEQRAVLFERLLTDELDVDQVGAFLVWGDPSLYDSTMRILDQVLARGKEAFEYQVIPGITSVQSLVARHRIPLNRI
GESILVTTGRRMATAPLQHPGNVVVMLDAHCTFERYTGQGLDIYWGAYLGTPDEILVAGRLDDVCEQIKRLRSEARERKG
WIMDTYLLRKPA

Sequences:

>Translated_252_residues
MKQILLIGMGAGDPEQITLQAVAALNLAEVIFILDKGYVDDQLLRLRKELCQRYITHQRYRLVQVQDPRREDDPEAYERG
IEGWHEQRAVLFERLLTDELDVDQVGAFLVWGDPSLYDSTMRILDQVLARGKEAFEYQVIPGITSVQSLVARHRIPLNRI
GESILVTTGRRMATAPLQHPGNVVVMLDAHCTFERYTGQGLDIYWGAYLGTPDEILVAGRLDDVCEQIKRLRSEARERKG
WIMDTYLLRKPA
>Mature_252_residues
MKQILLIGMGAGDPEQITLQAVAALNLAEVIFILDKGYVDDQLLRLRKELCQRYITHQRYRLVQVQDPRREDDPEAYERG
IEGWHEQRAVLFERLLTDELDVDQVGAFLVWGDPSLYDSTMRILDQVLARGKEAFEYQVIPGITSVQSLVARHRIPLNRI
GESILVTTGRRMATAPLQHPGNVVVMLDAHCTFERYTGQGLDIYWGAYLGTPDEILVAGRLDDVCEQIKRLRSEARERKG
WIMDTYLLRKPA

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28848; Mature: 28848

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILLIGMGAGDPEQITLQAVAALNLAEVIFILDKGYVDDQLLRLRKELCQRYITHQRY
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHE
RLVQVQDPRREDDPEAYERGIEGWHEQRAVLFERLLTDELDVDQVGAFLVWGDPSLYDST
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCHHHHHH
MRILDQVLARGKEAFEYQVIPGITSVQSLVARHRIPLNRIGESILVTTGRRMATAPLQHP
HHHHHHHHHCCCHHEEEEECCCHHHHHHHHHHHCCCHHHCCCEEEEECCCCCEECCCCCC
GNVVVMLDAHCTFERYTGQGLDIYWGAYLGTPDEILVAGRLDDVCEQIKRLRSEARERKG
CCEEEEEECCCCEEHHCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCC
WIMDTYLLRKPA
CEEEHHHHCCCC
>Mature Secondary Structure
MKQILLIGMGAGDPEQITLQAVAALNLAEVIFILDKGYVDDQLLRLRKELCQRYITHQRY
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHE
RLVQVQDPRREDDPEAYERGIEGWHEQRAVLFERLLTDELDVDQVGAFLVWGDPSLYDST
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCHHHHHH
MRILDQVLARGKEAFEYQVIPGITSVQSLVARHRIPLNRIGESILVTTGRRMATAPLQHP
HHHHHHHHHCCCHHEEEEECCCHHHHHHHHHHHCCCHHHCCCEEEEECCCCCEECCCCCC
GNVVVMLDAHCTFERYTGQGLDIYWGAYLGTPDEILVAGRLDDVCEQIKRLRSEARERKG
CCEEEEEECCCCEEHHCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCC
WIMDTYLLRKPA
CEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]