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The map label for this gene is melR [C]

Identifier: 66045677

GI number: 66045677

Start: 2826523

End: 2827446

Strand: Reverse

Name: melR [C]

Synonym: Psyr_2441

Alternate gene names: 66045677

Gene position: 2827446-2826523 (Counterclockwise)

Preceding gene: 66045679

Following gene: 66045676

Centisome position: 46.4

GC content: 57.14

Gene sequence:

>924_bases
ATGAACATGACATCGCCAATGAATAAAACAACAAGAATCGCCGACCCTTCCTACGAACTGATGGACGACCACAACGGTCT
GTCGATCATCTACCGCGAGCATGGTTTCCCCTGCCCGCTGGTGCGCTGGCACTTCCACAAGGAATATGAACTGCACCTGA
TCGTCGCCAGCTCCGGCAAGGTGTTTGTCGGCGACTACATCGGCAATTTCAATCCTGCCAGCCTGTTTCTCACCGGCCCC
AACCTGCCGCATAACTGGATCAGCCAGATCGACGACGGTGAAGTGGTGCCCAAGCGCGACATGCTGGTCAACTTTACCGA
TGAGCTGCTGGAAAGCGGCAACCAGGTGTTTGCCGAGCTCAAGACCCTGACGCCGTTATTGGAGCGCGCCCGCTACGGCA
TCGAATTTCGCTGCAAACGCACGATTCGTCAGGCCATGAAGCAGATGCAGAAAATCGCCGACTCGCGAGGCATTACTCGC
CTGGGCCATTTCTTCATTCTGCTCGAACTGCTCGCCGCCAGCGACGACTACCAGTTGCTGTCAGGCACGGCGGTCGCCCA
CACGGCGGACGAGCACAGCGTGGATCGCACCAACCGGGCGGTGGATTATATTTTCGCCCACTATGGCCGCGAGCTGCCGC
TGGAGGAAGTCGCCGAGTATCTGGGCATGAAACCGACCTATTTTTCCCGGGTGTTCAAACAGGCTACCGGGCGCTGCTTC
GTGGAGTTCGTCAACCGGCTGCGTATCAGCAAATCCTGCGAACTGCTCGCCGACGGCGACAAACCGGTCACCGATGTGTG
CTTCGAGTCCGGATTCAACAATATTTCCAACTTCAATCGGCGTTTTCAGCAACTCAAGGGCATGACTCCGTCGCACTACC
GCCGACTCGCCGTTCAGCGTCTGACCGAACAAAACCTGTACTGA

Upstream 100 bases:

>100_bases
GGTCAACGCCTCCTCTGTGCAGAGGCCTGATCGTAGGCGATTTTTGCCAATGACCGGGCATTGAACTGAAAAATCAGGCA
CATTACTCTTTTGGCAACAG

Downstream 100 bases:

>100_bases
TTCGCCCCGCCCTCGCCCTCATCGTCTACGCTGGAGTTGCGTCGAAGCCGCCCTATGGGCGATTCGGCGCTGTTGCCTTT
TCCCACCCGAGTGCAAAAAA

Product: helix-turn-helix, AraC type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNMTSPMNKTTRIADPSYELMDDHNGLSIIYREHGFPCPLVRWHFHKEYELHLIVASSGKVFVGDYIGNFNPASLFLTGP
NLPHNWISQIDDGEVVPKRDMLVNFTDELLESGNQVFAELKTLTPLLERARYGIEFRCKRTIRQAMKQMQKIADSRGITR
LGHFFILLELLAASDDYQLLSGTAVAHTADEHSVDRTNRAVDYIFAHYGRELPLEEVAEYLGMKPTYFSRVFKQATGRCF
VEFVNRLRISKSCELLADGDKPVTDVCFESGFNNISNFNRRFQQLKGMTPSHYRRLAVQRLTEQNLY

Sequences:

>Translated_307_residues
MNMTSPMNKTTRIADPSYELMDDHNGLSIIYREHGFPCPLVRWHFHKEYELHLIVASSGKVFVGDYIGNFNPASLFLTGP
NLPHNWISQIDDGEVVPKRDMLVNFTDELLESGNQVFAELKTLTPLLERARYGIEFRCKRTIRQAMKQMQKIADSRGITR
LGHFFILLELLAASDDYQLLSGTAVAHTADEHSVDRTNRAVDYIFAHYGRELPLEEVAEYLGMKPTYFSRVFKQATGRCF
VEFVNRLRISKSCELLADGDKPVTDVCFESGFNNISNFNRRFQQLKGMTPSHYRRLAVQRLTEQNLY
>Mature_307_residues
MNMTSPMNKTTRIADPSYELMDDHNGLSIIYREHGFPCPLVRWHFHKEYELHLIVASSGKVFVGDYIGNFNPASLFLTGP
NLPHNWISQIDDGEVVPKRDMLVNFTDELLESGNQVFAELKTLTPLLERARYGIEFRCKRTIRQAMKQMQKIADSRGITR
LGHFFILLELLAASDDYQLLSGTAVAHTADEHSVDRTNRAVDYIFAHYGRELPLEEVAEYLGMKPTYFSRVFKQATGRCF
VEFVNRLRISKSCELLADGDKPVTDVCFESGFNNISNFNRRFQQLKGMTPSHYRRLAVQRLTEQNLY

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=124, Percent_Identity=26.6129032258064, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35341; Mature: 35341

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTSPMNKTTRIADPSYELMDDHNGLSIIYREHGFPCPLVRWHFHKEYELHLIVASSGK
CCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCHHEEECCCCEEEEEEEECCCC
VFVGDYIGNFNPASLFLTGPNLPHNWISQIDDGEVVPKRDMLVNFTDELLESGNQVFAEL
EEEECCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCHHHHCCCHHHHHHCCHHHHHHH
KTLTPLLERARYGIEFRCKRTIRQAMKQMQKIADSRGITRLGHFFILLELLAASDDYQLL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
SGTAVAHTADEHSVDRTNRAVDYIFAHYGRELPLEEVAEYLGMKPTYFSRVFKQATGRCF
CCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
VEFVNRLRISKSCELLADGDKPVTDVCFESGFNNISNFNRRFQQLKGMTPSHYRRLAVQR
HHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTEQNLY
HHHHCCC
>Mature Secondary Structure
MNMTSPMNKTTRIADPSYELMDDHNGLSIIYREHGFPCPLVRWHFHKEYELHLIVASSGK
CCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCHHEEECCCCEEEEEEEECCCC
VFVGDYIGNFNPASLFLTGPNLPHNWISQIDDGEVVPKRDMLVNFTDELLESGNQVFAEL
EEEECCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCHHHHCCCHHHHHHCCHHHHHHH
KTLTPLLERARYGIEFRCKRTIRQAMKQMQKIADSRGITRLGHFFILLELLAASDDYQLL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
SGTAVAHTADEHSVDRTNRAVDYIFAHYGRELPLEEVAEYLGMKPTYFSRVFKQATGRCF
CCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
VEFVNRLRISKSCELLADGDKPVTDVCFESGFNNISNFNRRFQQLKGMTPSHYRRLAVQR
HHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTEQNLY
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]