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The map label for this gene is ribB [H]

Identifier: 66045638

GI number: 66045638

Start: 2784425

End: 2785534

Strand: Reverse

Name: ribB [H]

Synonym: Psyr_2402

Alternate gene names: 66045638

Gene position: 2785534-2784425 (Counterclockwise)

Preceding gene: 66045640

Following gene: 66045637

Centisome position: 45.71

GC content: 62.88

Gene sequence:

>1110_bases
ATGGCGTTCGATCGCATCGAAGACATCATTGAAGACTACCGCCAGGGCAAGATGGTGTTGCTGGTCGACGACGAAGACCG
GGAAAACGAAGGCGATCTGCTACTCGCCGCCGACTGCTGTTCACCACAGGCAATCAGTTTCATGGCTCGCGAAGCGCGCG
GTCTGATCTGCCTGACGCTGACCGACGAGCACTGTCAGCGTCTGGGCCTGGAACAGATGGTGCCCAGCAACGGCAGCGTA
TTCGCCACCGCATTCACGGTATCCATCGAGGCGACGACGGGTGTGACCACCGGCATCAGCGCGGCAGATCGTGCGCGTAC
CGTGCAGGCCGCCGTCAACCCGCACGCAGTACCGGAGGACCTGGTGCAGCCGGGCCATATCTTTCCATTGCGCGCTCGCG
ACGGCGGCGTGCTGACCCGCGTCGGGCATACCGAAGCGGGCTGCGACCTGGCCCGGCTGGCCGGTTTCACGCCAGCGTCG
GTCATCGTTGAAGTGATGAATGATGACGGCAGCATGGCCAGAAGACCCGACCTGGAAGTGTTCGCCAAAAAGCACGGTAT
TCGCATCGGCACCATCGCCGACCTGATCCATTACCGCCTGAGCACCGAACACACCATCGTCAGGATTGGCGAGCGCGAAC
TGCCGACCGTGCACGGCACCTTCCGTCTGTTCAGCTACGAAGACCGCATCGAAGGTGGCGTGCACATGGCCATGGTGATG
GGCGACATCCGGCGCGACGCCGCCACGCTGGTACGCGTGCATGTGGTCGACCCGCTGCGCGACCTGGTCGGCGCCGAATA
CAACGGGCCTGCCAACTGGACACTCTGGGCCGCCCTGCAACGTGTCGCGCAGGAAGGTCACGGTGTGGTAGTGGTGCTGG
CCAATCACGAATCGTCCCAGGCGCTTCTGGAGCGCATCCCGCAACTCACCCAGCCACCCCGTCAATACACCCGCTCGCAA
TCGCGCATTTATTCCGAGGTCGGTACGGGCGCACAGATCTTGCAGGACCTGGGCGTCGGCAAGCTGCGCCACCTCGGCCC
GCCACTGAAATACGCAGGGTTGACCGGCTACGATCTGGAAGTGATTGAAAGTATTCCGTTTCCCGGCTGA

Upstream 100 bases:

>100_bases
TTTCATCGCGATCTCACTGTTTCATTGATAGGCAATCTGTGGAATATTCTGTCTTATGGTATACCACGATTCATCCACCC
ATAAAACCGGGAAACTGACT

Downstream 100 bases:

>100_bases
CCAGGCAAAAACGTGTCACGCGAGCCCGATAATCCGCCGCCTGCAACCACAGGCGCTGACCGGAAACCGGACCATGAAGG
CGTTTTGAGAGGGCAAAACG

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCSPQAISFMAREARGLICLTLTDEHCQRLGLEQMVPSNGSV
FATAFTVSIEATTGVTTGISAADRARTVQAAVNPHAVPEDLVQPGHIFPLRARDGGVLTRVGHTEAGCDLARLAGFTPAS
VIVEVMNDDGSMARRPDLEVFAKKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVM
GDIRRDAATLVRVHVVDPLRDLVGAEYNGPANWTLWAALQRVAQEGHGVVVVLANHESSQALLERIPQLTQPPRQYTRSQ
SRIYSEVGTGAQILQDLGVGKLRHLGPPLKYAGLTGYDLEVIESIPFPG

Sequences:

>Translated_369_residues
MAFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCSPQAISFMAREARGLICLTLTDEHCQRLGLEQMVPSNGSV
FATAFTVSIEATTGVTTGISAADRARTVQAAVNPHAVPEDLVQPGHIFPLRARDGGVLTRVGHTEAGCDLARLAGFTPAS
VIVEVMNDDGSMARRPDLEVFAKKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVM
GDIRRDAATLVRVHVVDPLRDLVGAEYNGPANWTLWAALQRVAQEGHGVVVVLANHESSQALLERIPQLTQPPRQYTRSQ
SRIYSEVGTGAQILQDLGVGKLRHLGPPLKYAGLTGYDLEVIESIPFPG
>Mature_368_residues
AFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCSPQAISFMAREARGLICLTLTDEHCQRLGLEQMVPSNGSVF
ATAFTVSIEATTGVTTGISAADRARTVQAAVNPHAVPEDLVQPGHIFPLRARDGGVLTRVGHTEAGCDLARLAGFTPASV
IVEVMNDDGSMARRPDLEVFAKKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVMG
DIRRDAATLVRVHVVDPLRDLVGAEYNGPANWTLWAALQRVAQEGHGVVVVLANHESSQALLERIPQLTQPPRQYTRSQS
RIYSEVGTGAQILQDLGVGKLRHLGPPLKYAGLTGYDLEVIESIPFPG

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=50.2487562189055, Blast_Score=207, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=41.6666666666667, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40357; Mature: 40225

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCSPQAISFMAREARGLICLTL
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TDEHCQRLGLEQMVPSNGSVFATAFTVSIEATTGVTTGISAADRARTVQAAVNPHAVPED
CHHHHHHCCHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHH
LVQPGHIFPLRARDGGVLTRVGHTEAGCDLARLAGFTPASVIVEVMNDDGSMARRPDLEV
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHEEECCCCCCCCCCCHHH
FAKKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVM
HHHHCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEEEHHHHCCCEEEEHHH
GDIRRDAATLVRVHVVDPLRDLVGAEYNGPANWTLWAALQRVAQEGHGVVVVLANHESSQ
HHHHHHHHHEEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHH
ALLERIPQLTQPPRQYTRSQSRIYSEVGTGAQILQDLGVGKLRHLGPPLKYAGLTGYDLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHH
VIESIPFPG
HHHCCCCCC
>Mature Secondary Structure 
AFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCSPQAISFMAREARGLICLTL
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TDEHCQRLGLEQMVPSNGSVFATAFTVSIEATTGVTTGISAADRARTVQAAVNPHAVPED
CHHHHHHCCHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHH
LVQPGHIFPLRARDGGVLTRVGHTEAGCDLARLAGFTPASVIVEVMNDDGSMARRPDLEV
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHEEECCCCCCCCCCCHHH
FAKKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVM
HHHHCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEEEHHHHCCCEEEEHHH
GDIRRDAATLVRVHVVDPLRDLVGAEYNGPANWTLWAALQRVAQEGHGVVVVLANHESSQ
HHHHHHHHHEEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHH
ALLERIPQLTQPPRQYTRSQSRIYSEVGTGAQILQDLGVGKLRHLGPPLKYAGLTGYDLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHH
VIESIPFPG
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]