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The map label for this gene is potC [H]

Identifier: 66045635

GI number: 66045635

Start: 2781346

End: 2782161

Strand: Reverse

Name: potC [H]

Synonym: Psyr_2399

Alternate gene names: 66045635

Gene position: 2782161-2781346 (Counterclockwise)

Preceding gene: 66045636

Following gene: 66045634

Centisome position: 45.66

GC content: 62.13

Gene sequence:

>816_bases
ATGCTCCTGACACCCAATGCCATGAGCCCCGGCTTGCGTACGGGCCTGTACCTGACCACCGCCCTGATCGCGCTGTTCCT
GTTGCTGCCGATCCTGTTCATCGTCCTGCTGTCGTTCGGTTCCTCGCAGTGGCTGGTGTTCCCGCCGCCCGGCTGGACGC
TGAAGTGGTATCAGCAGTTTTTTTCCAACCCGGACTGGATGGCCGCGGCCATGTCCAGCTTCAAGGTCGCGATCCTGACC
ACCCTCGCCTCGGTGGCGCTGGGCCTGCCCACCGCGTTCGCACTGGTGCGTGGCCGGTTTCCGGGGCGTGATTTTCTGTA
CGGCGTCTTCACACTGCCGATGATCGTGCCGCTGGTGATCATCGCCGTCGCGGTCTACGCGCTGTTTCTCAAGCTCGGTT
ACACCGGCACATTGTTTTCCTTCGTCGTCAGCCATGTGATCGTCGCGTTGCCGTTCACCATCATCTCGATCATCAATTCG
CTGAAGCTGTTCGACCAGTCCATCGAGGATGCTGCGGTCATCTGCGGCGCTTCACGCTTGCAGGCCATCTACAAGGTGAC
CTTTCCCGGGATCCGGCCGGGCATGATGGCCGGCGCGCTGTTCGCGTTCCTGGTGTCGTGGGACGAGGTGGTGCTGAGCG
TGATGATGGCCAGCCCGACCCTGCAAACCCTTCCCGTGAAAATGTGGACCACCCTGCGTCAGGACCTGACGCCGGTCATC
GCCGTCGCCTCAACGCTGCTGATCGCCCTGTCGGTGCTGATCATGTTCATCGCCGCGACCCTGCGTCGCCGCAACGAAGC
CAGGAGTACGTCATGA

Upstream 100 bases:

>100_bases
CGCTGCGTTGTTGGTGCTGATCACGCTGGTGCTGTTCTACTTCTACCTGAAGCTCCAGCCGGAATCACCGGTCGGCGCCA
GCAACGCGAGGTAAACCGCC

Downstream 100 bases:

>100_bases
GTGCCGTGATCAAAGACCCCGCCCATCAGCCACACAACACACTGGTCAGCCTGTGTAATCTGAACAAGCACTATGGAAAT
TTCGCCGCCGTCGACGACAT

Product: binding-protein dependent transport system inner membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLLTPNAMSPGLRTGLYLTTALIALFLLLPILFIVLLSFGSSQWLVFPPPGWTLKWYQQFFSNPDWMAAAMSSFKVAILT
TLASVALGLPTAFALVRGRFPGRDFLYGVFTLPMIVPLVIIAVAVYALFLKLGYTGTLFSFVVSHVIVALPFTIISIINS
LKLFDQSIEDAAVICGASRLQAIYKVTFPGIRPGMMAGALFAFLVSWDEVVLSVMMASPTLQTLPVKMWTTLRQDLTPVI
AVASTLLIALSVLIMFIAATLRRRNEARSTS

Sequences:

>Translated_271_residues
MLLTPNAMSPGLRTGLYLTTALIALFLLLPILFIVLLSFGSSQWLVFPPPGWTLKWYQQFFSNPDWMAAAMSSFKVAILT
TLASVALGLPTAFALVRGRFPGRDFLYGVFTLPMIVPLVIIAVAVYALFLKLGYTGTLFSFVVSHVIVALPFTIISIINS
LKLFDQSIEDAAVICGASRLQAIYKVTFPGIRPGMMAGALFAFLVSWDEVVLSVMMASPTLQTLPVKMWTTLRQDLTPVI
AVASTLLIALSVLIMFIAATLRRRNEARSTS
>Mature_271_residues
MLLTPNAMSPGLRTGLYLTTALIALFLLLPILFIVLLSFGSSQWLVFPPPGWTLKWYQQFFSNPDWMAAAMSSFKVAILT
TLASVALGLPTAFALVRGRFPGRDFLYGVFTLPMIVPLVIIAVAVYALFLKLGYTGTLFSFVVSHVIVALPFTIISIINS
LKLFDQSIEDAAVICGASRLQAIYKVTFPGIRPGMMAGALFAFLVSWDEVVLSVMMASPTLQTLPVKMWTTLRQDLTPVI
AVASTLLIALSVLIMFIAATLRRRNEARSTS

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=31.1965811965812, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787081, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787714, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787571, Length=254, Percent_Identity=26.3779527559055, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788764, Length=165, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29631; Mature: 29631

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]