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The map label for this gene is fhuA [H]

Identifier: 66045469

GI number: 66045469

Start: 2590553

End: 2592664

Strand: Reverse

Name: fhuA [H]

Synonym: Psyr_2229

Alternate gene names: 66045469

Gene position: 2592664-2590553 (Counterclockwise)

Preceding gene: 66045470

Following gene: 66045468

Centisome position: 42.55

GC content: 60.8

Gene sequence:

>2112_bases
ATGTCGTCTCGTAGAATCGTGTCTCTGGCAGGCTTGGCAATCGGGGTTTTTGGCAACACGGGTTACGCGGAGGAAAGCCC
GCAGACCATTGAACTGGAAAGCGTCAACGTCACTTCCGACTATCAGTACGAGACGGCGACCAGCCCGGTCCAGGGCTATC
GCGCCACCCGCTCGGCCACGGCCACCAAGACCGACACCGCCATCGCGGATATCCCGCAGTCGATCAGCGTCGTACCTGCC
TCAGTACTCAAGGACCTTGGCAGCAACAATGTCGAGCGCGCGCTGGATTTTGCCGGCGGCGTATCCAAGCAGAATAACTT
CGGCGGTCTGACGCTTTACGAGTACAGCATCCGCGGCTTCACCACGTCCGAGTTCTACAAGGACGGCTTCAGCGCCAACC
GCGGTTACCCAGCCACGCCGGATGCCGCAAATATCGAACGTATCGAAGTGCTCAAAGGCCCCGCCGCCAGCCTGTACGGG
CGTGGCGATCCGGGCGGCACGGTCAACATCGTCAGCAAAAAACCCCAGCGTGAAGCCTTTACCACCTTGCAGACCAGCGC
AGGCAGTTGGGATCGCTATCGCACCGCGCTGGACGTCAACACGCCGCTGGATGAAGAAGGCAATCTGCTTTCGCGGGTCA
ATCTGGCCGTCGAAGACAACAACAGCTTTCGTGACCATGTAGAGAGCAAACGGGTGTTTGTCGCCCCATCCTTCAGCTGG
CAATTGAACCCTGACACCCGTCTGCTGCTGGAAACCGAGTTCGTGCGCCACACATCGACGTTCGACCGAGGCGTGGTCGC
CCCCAACAACAAGTGGAGTGGCGTGTCGCGCTCGACCTTCCTCGGTGAGCCGGACGATGACATCGATAATGACAACAATA
TGGTGCAGTTCGCCCTGGACCACCAGCTCAACGATGTGTGGTCGCTGCGTCTGGCCAGCCATTACAAACAGGGCGAGATG
TCGGGTTTTGCCAGCGAGGCGCGCCCGCTGAATGCCGACGGGCACACGGTCAATCGCCGTTACCGTGAGCGCGACAACAA
CTGGCATGACAGCATCACCCAGTTGGAGTTGCGCGGCCGTTTCGACGGCCTGGGCGTCGAGCACGAGGTGCTGATCGGCA
CCGAGTACGAGAACTATCGCAAGAACGAACGCGTCACGACCATCGCCGGCAGCCCCTACGCCATCGACATCTACAACCCG
GTCTACGGCCAGCCGAAACCCGCTGGCGCACGCTCCGGTACTGATTTTTACGAGCATGTCGAAAGCCGCGCGCTGAACCT
GCAGGACCAGATTGTCTTTACCGACAAGCTGCGCGGCATGATCGGGGCACGCTACGAGCACTTCGATCAGCAGGTCGATG
ACTTCACCACCAACGCCACTTCCGGGCAGCGCCAGGACGCTTTCACTCAACGCGCCGGGTTGCTTTATCAACTCACACCG
CAGGTCGGCCTGTTCGCCAATGCCTCCACCTCGTTCAAGCCCAACAATGGCCTGGACGCCGCCGGCAAAACCTTCGACCC
GGAAGAAGGCGTCGGCTACGAAGTCGGAATCAAAAGCGAACTGTTCGACCATCGCCTGAGCACGACCCTCGCCGCCTTTC
ATATCGAAAAGGAAAACGTTCTGGCCCTGGACCCCGGCACCGACACCAATCGCGCGGTGGGCAAGGCTCGCAGCCAGGGC
TTCGACGTGCAATTTACCGGGCAGGTCAGCGAAGCCGTTCGGGTCATCGGTGCCTTCGCCTACATCGACGCCGAAGTGAC
CAAGGGCGACCAGAGCATCCCCACGGGCAGTCGCATCCTCGGTGTCGCCAAACACAGCGGCAGCCTGCTGGGCGTCTATG
AGTTCCAGGAAGGCGCGTTGCGCGGCTCGGACGTGGGCGCGGCGTACACCTACGTCGGCGACCGCTCGGGGCAGTCGGGC
GCTGACTTCGAGTTGCCGGCCTACCAGACCGTAGACCTGCTGGCGCATTACAAAGCCAGCGACAACGTCACGGTGGGTTT
GAACCTGAACAACATTTTCGATGAAAAATACTACGAGCGCTCCTACAGCAACTACTGGGTCGCGCCTGGCGAACCGCGCA
ACGTTACGGTCAGCCTGACCCTCAGCCTCTGA

Upstream 100 bases:

>100_bases
GCCTGCTGATAGATGCGACGGTTACATCTCCCCTTCAACAAACAGCAATAATTCTCAACGGAGATGTTATATTGTATCTA
TTACTATCAGGAAGTCTCAC

Downstream 100 bases:

>100_bases
CGCCCATGAGACCCGGTCCAATACACCTCCGCTCACAACAACAAGGACGCATCATGCTTTCAAGCAAACCTTTCCTGGCC
CTGAGCCTGCTCGGCGCTCT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MSSRRIVSLAGLAIGVFGNTGYAEESPQTIELESVNVTSDYQYETATSPVQGYRATRSATATKTDTAIADIPQSISVVPA
SVLKDLGSNNVERALDFAGGVSKQNNFGGLTLYEYSIRGFTTSEFYKDGFSANRGYPATPDAANIERIEVLKGPAASLYG
RGDPGGTVNIVSKKPQREAFTTLQTSAGSWDRYRTALDVNTPLDEEGNLLSRVNLAVEDNNSFRDHVESKRVFVAPSFSW
QLNPDTRLLLETEFVRHTSTFDRGVVAPNNKWSGVSRSTFLGEPDDDIDNDNNMVQFALDHQLNDVWSLRLASHYKQGEM
SGFASEARPLNADGHTVNRRYRERDNNWHDSITQLELRGRFDGLGVEHEVLIGTEYENYRKNERVTTIAGSPYAIDIYNP
VYGQPKPAGARSGTDFYEHVESRALNLQDQIVFTDKLRGMIGARYEHFDQQVDDFTTNATSGQRQDAFTQRAGLLYQLTP
QVGLFANASTSFKPNNGLDAAGKTFDPEEGVGYEVGIKSELFDHRLSTTLAAFHIEKENVLALDPGTDTNRAVGKARSQG
FDVQFTGQVSEAVRVIGAFAYIDAEVTKGDQSIPTGSRILGVAKHSGSLLGVYEFQEGALRGSDVGAAYTYVGDRSGQSG
ADFELPAYQTVDLLAHYKASDNVTVGLNLNNIFDEKYYERSYSNYWVAPGEPRNVTVSLTLSL

Sequences:

>Translated_703_residues
MSSRRIVSLAGLAIGVFGNTGYAEESPQTIELESVNVTSDYQYETATSPVQGYRATRSATATKTDTAIADIPQSISVVPA
SVLKDLGSNNVERALDFAGGVSKQNNFGGLTLYEYSIRGFTTSEFYKDGFSANRGYPATPDAANIERIEVLKGPAASLYG
RGDPGGTVNIVSKKPQREAFTTLQTSAGSWDRYRTALDVNTPLDEEGNLLSRVNLAVEDNNSFRDHVESKRVFVAPSFSW
QLNPDTRLLLETEFVRHTSTFDRGVVAPNNKWSGVSRSTFLGEPDDDIDNDNNMVQFALDHQLNDVWSLRLASHYKQGEM
SGFASEARPLNADGHTVNRRYRERDNNWHDSITQLELRGRFDGLGVEHEVLIGTEYENYRKNERVTTIAGSPYAIDIYNP
VYGQPKPAGARSGTDFYEHVESRALNLQDQIVFTDKLRGMIGARYEHFDQQVDDFTTNATSGQRQDAFTQRAGLLYQLTP
QVGLFANASTSFKPNNGLDAAGKTFDPEEGVGYEVGIKSELFDHRLSTTLAAFHIEKENVLALDPGTDTNRAVGKARSQG
FDVQFTGQVSEAVRVIGAFAYIDAEVTKGDQSIPTGSRILGVAKHSGSLLGVYEFQEGALRGSDVGAAYTYVGDRSGQSG
ADFELPAYQTVDLLAHYKASDNVTVGLNLNNIFDEKYYERSYSNYWVAPGEPRNVTVSLTLSL
>Mature_702_residues
SSRRIVSLAGLAIGVFGNTGYAEESPQTIELESVNVTSDYQYETATSPVQGYRATRSATATKTDTAIADIPQSISVVPAS
VLKDLGSNNVERALDFAGGVSKQNNFGGLTLYEYSIRGFTTSEFYKDGFSANRGYPATPDAANIERIEVLKGPAASLYGR
GDPGGTVNIVSKKPQREAFTTLQTSAGSWDRYRTALDVNTPLDEEGNLLSRVNLAVEDNNSFRDHVESKRVFVAPSFSWQ
LNPDTRLLLETEFVRHTSTFDRGVVAPNNKWSGVSRSTFLGEPDDDIDNDNNMVQFALDHQLNDVWSLRLASHYKQGEMS
GFASEARPLNADGHTVNRRYRERDNNWHDSITQLELRGRFDGLGVEHEVLIGTEYENYRKNERVTTIAGSPYAIDIYNPV
YGQPKPAGARSGTDFYEHVESRALNLQDQIVFTDKLRGMIGARYEHFDQQVDDFTTNATSGQRQDAFTQRAGLLYQLTPQ
VGLFANASTSFKPNNGLDAAGKTFDPEEGVGYEVGIKSELFDHRLSTTLAAFHIEKENVLALDPGTDTNRAVGKARSQGF
DVQFTGQVSEAVRVIGAFAYIDAEVTKGDQSIPTGSRILGVAKHSGSLLGVYEFQEGALRGSDVGAAYTYVGDRSGQSGA
DFELPAYQTVDLLAHYKASDNVTVGLNLNNIFDEKYYERSYSNYWVAPGEPRNVTVSLTLSL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=743, Percent_Identity=27.1870794078062, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1787344, Length=705, Percent_Identity=25.8156028368794, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1787024, Length=770, Percent_Identity=25.5844155844156, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787723, Length=654, Percent_Identity=22.17125382263, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77267; Mature: 77135

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRRIVSLAGLAIGVFGNTGYAEESPQTIELESVNVTSDYQYETATSPVQGYRATRSAT
CCCCEEEEEECEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCC
ATKTDTAIADIPQSISVVPASVLKDLGSNNVERALDFAGGVSKQNNFGGLTLYEYSIRGF
CCCCCCHHHHCCCCHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
TTSEFYKDGFSANRGYPATPDAANIERIEVLKGPAASLYGRGDPGGTVNIVSKKPQREAF
CHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCEEEEECCCCCHHHH
TTLQTSAGSWDRYRTALDVNTPLDEEGNLLSRVNLAVEDNNSFRDHVESKRVFVAPSFSW
HHHHCCCCCCHHEEEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHCCCEEEEECCCEE
QLNPDTRLLLETEFVRHTSTFDRGVVAPNNKWSGVSRSTFLGEPDDDIDNDNNMVQFALD
EECCCCEEEEEEHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
HQLNDVWSLRLASHYKQGEMSGFASEARPLNADGHTVNRRYRERDNNWHDSITQLELRGR
CCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHCCCEEEEEECC
FDGLGVEHEVLIGTEYENYRKNERVTTIAGSPYAIDIYNPVYGQPKPAGARSGTDFYEHV
CCCCCCCEEEEEECCHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
ESRALNLQDQIVFTDKLRGMIGARYEHFDQQVDDFTTNATSGQRQDAFTQRAGLLYQLTP
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEECC
QVGLFANASTSFKPNNGLDAAGKTFDPEEGVGYEVGIKSELFDHRLSTTLAAFHIEKENV
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEEEEECCCCE
LALDPGTDTNRAVGKARSQGFDVQFTGQVSEAVRVIGAFAYIDAEVTKGDQSIPTGSRIL
EEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEE
GVAKHSGSLLGVYEFQEGALRGSDVGAAYTYVGDRSGQSGADFELPAYQTVDLLAHYKAS
EEEECCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCC
DNVTVGLNLNNIFDEKYYERSYSNYWVAPGEPRNVTVSLTLSL
CCEEEEEEHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEEC
>Mature Secondary Structure 
SSRRIVSLAGLAIGVFGNTGYAEESPQTIELESVNVTSDYQYETATSPVQGYRATRSAT
CCCEEEEEECEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCC
ATKTDTAIADIPQSISVVPASVLKDLGSNNVERALDFAGGVSKQNNFGGLTLYEYSIRGF
CCCCCCHHHHCCCCHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
TTSEFYKDGFSANRGYPATPDAANIERIEVLKGPAASLYGRGDPGGTVNIVSKKPQREAF
CHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCEEEEECCCCCHHHH
TTLQTSAGSWDRYRTALDVNTPLDEEGNLLSRVNLAVEDNNSFRDHVESKRVFVAPSFSW
HHHHCCCCCCHHEEEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHCCCEEEEECCCEE
QLNPDTRLLLETEFVRHTSTFDRGVVAPNNKWSGVSRSTFLGEPDDDIDNDNNMVQFALD
EECCCCEEEEEEHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
HQLNDVWSLRLASHYKQGEMSGFASEARPLNADGHTVNRRYRERDNNWHDSITQLELRGR
CCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHCCCEEEEEECC
FDGLGVEHEVLIGTEYENYRKNERVTTIAGSPYAIDIYNPVYGQPKPAGARSGTDFYEHV
CCCCCCCEEEEEECCHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
ESRALNLQDQIVFTDKLRGMIGARYEHFDQQVDDFTTNATSGQRQDAFTQRAGLLYQLTP
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEECC
QVGLFANASTSFKPNNGLDAAGKTFDPEEGVGYEVGIKSELFDHRLSTTLAAFHIEKENV
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEEEEECCCCE
LALDPGTDTNRAVGKARSQGFDVQFTGQVSEAVRVIGAFAYIDAEVTKGDQSIPTGSRIL
EEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEE
GVAKHSGSLLGVYEFQEGALRGSDVGAAYTYVGDRSGQSGADFELPAYQTVDLLAHYKAS
EEEECCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCC
DNVTVGLNLNNIFDEKYYERSYSNYWVAPGEPRNVTVSLTLSL
CCEEEEEEHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]