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The map label for this gene is ureC

Identifier: 66045437

GI number: 66045437

Start: 2554495

End: 2556207

Strand: Reverse

Name: ureC

Synonym: Psyr_2197

Alternate gene names: 66045437

Gene position: 2556207-2554495 (Counterclockwise)

Preceding gene: 66045438

Following gene: 66045436

Centisome position: 41.95

GC content: 63.28

Gene sequence:

>1713_bases
ATGGCAACGATGACGCGCAAGGAATACGCCGCCATGTACGGCCCCACGACTGGCGATGCCGTGCGCCTGGGCGACACCTC
GCTGCTGGCCGAAGTCGAGTTCGACCACTCGGTACCCGGTGATGAGTGCCTGCACGGCGGTGGCAAGACGCTGCGTGACG
GCATGGGCCTGATGCCCGGGCATGACAGCGTTGACGGCGCCCTCGATATGCTGATCTGCAACGCGCTGATCATCGACCCG
GTGATCGGCATCGTCAAAGGCGACATCGGTATCAAGGACGGCAAGATCGTGGCCATTGGCAAGGCCGGCAACCCGCAGAT
CATGGACGGCGTACACCCGCAACTGATCTGCGGCGTCGCCACGACCGTACGCGATGCCGAGGGCCTGATCGTCACCCCCG
GCGGCATCGACGTGCACGTGCATTTCGACTCTGCGCAACTCTGCGATCACGCGCTGGCGGCAGGCCTGACCACACTGATC
GGCGGCTCGCTGGGGCCGATCACGGTCGGCATCGATTGTGGCGGGGAATGGAACGTCGGCAAGATGCTGCAAGCCGCCGA
GGCCTGGCCGATCAACTTCGGCTTTCTCGGACGCGGCAATTCCAGCAAGCCCGAATCGCTGCTCGGGCAACTGCGTGGCG
GTTGCCTGGGGCTGAAGATTCACGAGGACTGGGGCGCCATGCCAGCGGTGATCGACACCTGCCTGAAAGTCGCCGACGAA
TACGACTTTCAGGTGCAGTTGCACACCGACACGCTCAATGAATCCGGGTTTCTCGAAGACACGCTGGCGGCCATCGGCGA
CCGCACCATCCACATGTACCACACCGAAGGTGCAGGTGGCGGGCATGCGCCGGACATCATCAGCGTCGCCGGCAAAAGCA
ACTGCATCCCCTCCTCGACCAACCCGACCAACCCCTACACCGTGAATACATTCGACGAGCACCTGGACATGATCATGGTC
TGTCACCACCTCAATCCGGATGTGCCGGAAGACGTGGCGTTCGCCGAATCGCGGGTGCGCCCGCAGACCATTGCCGCCGA
GGACATCCTGCACGACACCGGCGCCATTTCGATCCTGGGCTCCGACAGTCAGGGCATGGGCCGTATCAACGAGGTGATCT
GCCGGACCTGGCAACTGGCGTCAAAAATGAAAGACCAGCGCGGTCGCCTGCCGGAAGAAACCACGGCACTGGGCGACAAC
GAACGGATCAAGCGTTACATCGCCAAATACACCATCAATGCCGCGCGGGTATTCGGCATAGACAGCTACATCGGCTCTCT
GGAGCCCGGCAAGCTGGCCGATCTGGTGCTCTGGCGGCCGGCCTTCTTCGGCATCAAGCCGGAACTGGTGGTCAAGGGTG
GCTTCATCGTGCACGCCGTGATGGGTGATTCCGCCGCCTCGCTGTACACCTGCGAACCCTTGGTGATGCGCCCGCAATGG
GGCGCGTTTGGCGAGGCCAAACAGGCGCTGTCGGTCAACTTCGTCAATCGTCTTGCCGTCGAAGCCGACACCGCCACGCG
CCTGGGGCTCAAGAAGCAACTGCTGCCCGCGTTCGGCACTCGCACCCTGCGCAAGTCCGACATGCTGCACAACGATGCCT
GCCCGGATATCCGCGTCGACCCGCAGACTTTCGATGTGTACGCCGACGGCGAGCGCCTGCACTGCGAGCCGGTCAGCGAA
GTGCCACTTGCGCAGCGCTACATGCTGCGTTGA

Upstream 100 bases:

>100_bases
CGGCTTCAGTGGCCTGACCAATGGCAACCTGCACGATCCGGCCTGCAAGCTCGCAGCGCTGGAGCGTGCCCGCGCCCAAT
TCTTCAAAGGAGCCTGAGGC

Downstream 100 bases:

>100_bases
AACCCACCCCGCAGAGGAAACCCGACAATGAGCCTGCCCTTGAACGCATCTGCCCCGCACACCGATGCCCAACCCCATCC
CGGCGCTGCTCGCGTGGGCA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha 1

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MATMTRKEYAAMYGPTTGDAVRLGDTSLLAEVEFDHSVPGDECLHGGGKTLRDGMGLMPGHDSVDGALDMLICNALIIDP
VIGIVKGDIGIKDGKIVAIGKAGNPQIMDGVHPQLICGVATTVRDAEGLIVTPGGIDVHVHFDSAQLCDHALAAGLTTLI
GGSLGPITVGIDCGGEWNVGKMLQAAEAWPINFGFLGRGNSSKPESLLGQLRGGCLGLKIHEDWGAMPAVIDTCLKVADE
YDFQVQLHTDTLNESGFLEDTLAAIGDRTIHMYHTEGAGGGHAPDIISVAGKSNCIPSSTNPTNPYTVNTFDEHLDMIMV
CHHLNPDVPEDVAFAESRVRPQTIAAEDILHDTGAISILGSDSQGMGRINEVICRTWQLASKMKDQRGRLPEETTALGDN
ERIKRYIAKYTINAARVFGIDSYIGSLEPGKLADLVLWRPAFFGIKPELVVKGGFIVHAVMGDSAASLYTCEPLVMRPQW
GAFGEAKQALSVNFVNRLAVEADTATRLGLKKQLLPAFGTRTLRKSDMLHNDACPDIRVDPQTFDVYADGERLHCEPVSE
VPLAQRYMLR

Sequences:

>Translated_570_residues
MATMTRKEYAAMYGPTTGDAVRLGDTSLLAEVEFDHSVPGDECLHGGGKTLRDGMGLMPGHDSVDGALDMLICNALIIDP
VIGIVKGDIGIKDGKIVAIGKAGNPQIMDGVHPQLICGVATTVRDAEGLIVTPGGIDVHVHFDSAQLCDHALAAGLTTLI
GGSLGPITVGIDCGGEWNVGKMLQAAEAWPINFGFLGRGNSSKPESLLGQLRGGCLGLKIHEDWGAMPAVIDTCLKVADE
YDFQVQLHTDTLNESGFLEDTLAAIGDRTIHMYHTEGAGGGHAPDIISVAGKSNCIPSSTNPTNPYTVNTFDEHLDMIMV
CHHLNPDVPEDVAFAESRVRPQTIAAEDILHDTGAISILGSDSQGMGRINEVICRTWQLASKMKDQRGRLPEETTALGDN
ERIKRYIAKYTINAARVFGIDSYIGSLEPGKLADLVLWRPAFFGIKPELVVKGGFIVHAVMGDSAASLYTCEPLVMRPQW
GAFGEAKQALSVNFVNRLAVEADTATRLGLKKQLLPAFGTRTLRKSDMLHNDACPDIRVDPQTFDVYADGERLHCEPVSE
VPLAQRYMLR
>Mature_569_residues
ATMTRKEYAAMYGPTTGDAVRLGDTSLLAEVEFDHSVPGDECLHGGGKTLRDGMGLMPGHDSVDGALDMLICNALIIDPV
IGIVKGDIGIKDGKIVAIGKAGNPQIMDGVHPQLICGVATTVRDAEGLIVTPGGIDVHVHFDSAQLCDHALAAGLTTLIG
GSLGPITVGIDCGGEWNVGKMLQAAEAWPINFGFLGRGNSSKPESLLGQLRGGCLGLKIHEDWGAMPAVIDTCLKVADEY
DFQVQLHTDTLNESGFLEDTLAAIGDRTIHMYHTEGAGGGHAPDIISVAGKSNCIPSSTNPTNPYTVNTFDEHLDMIMVC
HHLNPDVPEDVAFAESRVRPQTIAAEDILHDTGAISILGSDSQGMGRINEVICRTWQLASKMKDQRGRLPEETTALGDNE
RIKRYIAKYTINAARVFGIDSYIGSLEPGKLADLVLWRPAFFGIKPELVVKGGFIVHAVMGDSAASLYTCEPLVMRPQWG
AFGEAKQALSVNFVNRLAVEADTATRLGLKKQLLPAFGTRTLRKSDMLHNDACPDIRVDPQTFDVYADGERLHCEPVSEV
PLAQRYMLR

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE11_PSEU2 (Q4ZUD2)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_235278.1
- ProteinModelPortal:   Q4ZUD2
- SMR:   Q4ZUD2
- STRING:   Q4ZUD2
- GeneID:   3367712
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_2197
- NMPDR:   fig|205918.4.peg.2674
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   VNTFDEH
- ProtClustDB:   PRK13308
- BioCyc:   PSYR205918:PSYR_2197-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61200; Mature: 61068

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 322-322 BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMTRKEYAAMYGPTTGDAVRLGDTSLLAEVEFDHSVPGDECLHGGGKTLRDGMGLMPG
CCCCCCHHHHHHCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCHHHCCCCCCCC
HDSVDGALDMLICNALIIDPVIGIVKGDIGIKDGKIVAIGKAGNPQIMDGVHPQLICGVA
CCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCHHCCCCCHHHHHHHH
TTVRDAEGLIVTPGGIDVHVHFDSAQLCDHALAAGLTTLIGGSLGPITVGIDCGGEWNVG
HHHCCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
KMLQAAEAWPINFGFLGRGNSSKPESLLGQLRGGCLGLKIHEDWGAMPAVIDTCLKVADE
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDFQVQLHTDTLNESGFLEDTLAAIGDRTIHMYHTEGAGGGHAPDIISVAGKSNCIPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCC
NPTNPYTVNTFDEHLDMIMVCHHLNPDVPEDVAFAESRVRPQTIAAEDILHDTGAISILG
CCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEE
SDSQGMGRINEVICRTWQLASKMKDQRGRLPEETTALGDNERIKRYIAKYTINAARVFGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCHHEEEEE
DSYIGSLEPGKLADLVLWRPAFFGIKPELVVKGGFIVHAVMGDSAASLYTCEPLVMRPQW
HHHHCCCCCCCHHHHEEECHHHHCCCCEEEEECCEEEEEEECCCCCCEEECCCEEECCCC
GAFGEAKQALSVNFVNRLAVEADTATRLGLKKQLLPAFGTRTLRKSDMLHNDACPDIRVD
CCCCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEC
PQTFDVYADGERLHCEPVSEVPLAQRYMLR
CCEEEEEECCCEEECCCCCCCCHHHHHHCC
>Mature Secondary Structure 
ATMTRKEYAAMYGPTTGDAVRLGDTSLLAEVEFDHSVPGDECLHGGGKTLRDGMGLMPG
CCCCCHHHHHHCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCHHHCCCCCCCC
HDSVDGALDMLICNALIIDPVIGIVKGDIGIKDGKIVAIGKAGNPQIMDGVHPQLICGVA
CCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCHHCCCCCHHHHHHHH
TTVRDAEGLIVTPGGIDVHVHFDSAQLCDHALAAGLTTLIGGSLGPITVGIDCGGEWNVG
HHHCCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
KMLQAAEAWPINFGFLGRGNSSKPESLLGQLRGGCLGLKIHEDWGAMPAVIDTCLKVADE
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCC
YDFQVQLHTDTLNESGFLEDTLAAIGDRTIHMYHTEGAGGGHAPDIISVAGKSNCIPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCC
NPTNPYTVNTFDEHLDMIMVCHHLNPDVPEDVAFAESRVRPQTIAAEDILHDTGAISILG
CCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEE
SDSQGMGRINEVICRTWQLASKMKDQRGRLPEETTALGDNERIKRYIAKYTINAARVFGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCHHEEEEE
DSYIGSLEPGKLADLVLWRPAFFGIKPELVVKGGFIVHAVMGDSAASLYTCEPLVMRPQW
HHHHCCCCCCCHHHHEEECHHHHCCCCEEEEECCEEEEEEECCCCCCEEECCCEEECCCC
GAFGEAKQALSVNFVNRLAVEADTATRLGLKKQLLPAFGTRTLRKSDMLHNDACPDIRVD
CCCCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEC
PQTFDVYADGERLHCEPVSEVPLAQRYMLR
CCEEEEEECCCEEECCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA