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The map label for this gene is tatD [H]

Identifier: 66045300

GI number: 66045300

Start: 2406820

End: 2407641

Strand: Reverse

Name: tatD [H]

Synonym: Psyr_2060

Alternate gene names: 66045300

Gene position: 2407641-2406820 (Counterclockwise)

Preceding gene: 66045306

Following gene: 66045299

Centisome position: 39.51

GC content: 61.56

Gene sequence:

>822_bases
ATGCAACTCATCGACATCGGCGTCAATCTGACCAACGCAAGCTTCGCCTCGCAGCGACAGGCGGTACTCGACCGCGCCTA
TGCCGCAGGCGTCGAACAACTGGTGGTGACCGGCACCAGTGTCGAGGGCAGCGAACACGCCCTGCAGCTGTGTCACGAGC
TGGATGAAAGCGCGCAACGCCTGTTCTGCACGGCAGGTATCCATCCGCATTCGGCGAGCGATTGGACCGGTGACACCGAG
AAACAGTTGCATGCCCTGCTCAAGGAAAATCGCGTTCGCGCCGTGGGTGAATGCGGCCTGGATTACAATCGCGATTTCTC
GCCTCGCCCCAAACAGGAAAAGGTCCTGGAGGCGCACCTGGCCATGGCCGTGGAACTGCAATTACCGGTGTTCCTCCACG
AACGCGATGCCAACCAGCGGCTGCTGGAAATTTTGCGCGATTACCGCGACCGCCTGCCCGCGGCGGTTGTGCACTGTTTC
ACCGGCGAGCGCGCCGCGCTGTTCAGTTACCTGGACCTTGACCTGCATATCGGCATCACCGGCTGGATCTGCGACGAACG
ACGCGGCACCCACCTGCACGCGCTGGTGGGCAATATCCCTCGCGGCCGGCTGATGCTGGAAAGCGATGCGCCCTACCTGC
TGCCACGCAGCCTGCGCCCCAAGCCGAAAAACGGTCGCAACGAGCCGGCTTACCTGCCGGAAGTCTTGCGCGAAGTAGCC
TTGCATCGGGGCGAAACGCAGGAAGACCTCGCACGCCACAGCACGGATTGCGCACGGCAGTTTTTTGCTTTGCCGACGCT
GAAAAAATCCACAGAGGATTAA

Upstream 100 bases:

>100_bases
AATCGTTGAACCTTGAGGTTCAATCGCTTGAATACCCAGCGTTTTCTTGTTGTGGCCAGAGCTCTGGTATGCTCGGCAGC
CTTCAGCTGGAGGTAGCACC

Downstream 100 bases:

>100_bases
AATCTGCGGCTTTGTTGACCCGTATCAAAGGGCTCTTCGGTGGTTGAGGCACAGTGATGGCATCTTGCTGCTACTTCAAC
CGATTACCGAAGAAGACCCC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MQLIDIGVNLTNASFASQRQAVLDRAYAAGVEQLVVTGTSVEGSEHALQLCHELDESAQRLFCTAGIHPHSASDWTGDTE
KQLHALLKENRVRAVGECGLDYNRDFSPRPKQEKVLEAHLAMAVELQLPVFLHERDANQRLLEILRDYRDRLPAAVVHCF
TGERAALFSYLDLDLHIGITGWICDERRGTHLHALVGNIPRGRLMLESDAPYLLPRSLRPKPKNGRNEPAYLPEVLREVA
LHRGETQEDLARHSTDCARQFFALPTLKKSTED

Sequences:

>Translated_273_residues
MQLIDIGVNLTNASFASQRQAVLDRAYAAGVEQLVVTGTSVEGSEHALQLCHELDESAQRLFCTAGIHPHSASDWTGDTE
KQLHALLKENRVRAVGECGLDYNRDFSPRPKQEKVLEAHLAMAVELQLPVFLHERDANQRLLEILRDYRDRLPAAVVHCF
TGERAALFSYLDLDLHIGITGWICDERRGTHLHALVGNIPRGRLMLESDAPYLLPRSLRPKPKNGRNEPAYLPEVLREVA
LHRGETQEDLARHSTDCARQFFALPTLKKSTED
>Mature_273_residues
MQLIDIGVNLTNASFASQRQAVLDRAYAAGVEQLVVTGTSVEGSEHALQLCHELDESAQRLFCTAGIHPHSASDWTGDTE
KQLHALLKENRVRAVGECGLDYNRDFSPRPKQEKVLEAHLAMAVELQLPVFLHERDANQRLLEILRDYRDRLPAAVVHCF
TGERAALFSYLDLDLHIGITGWICDERRGTHLHALVGNIPRGRLMLESDAPYLLPRSLRPKPKNGRNEPAYLPEVLREVA
LHRGETQEDLARHSTDCARQFFALPTLKKSTED

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=286, Percent_Identity=31.4685314685315, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI225903439, Length=243, Percent_Identity=31.2757201646091, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI225903424, Length=178, Percent_Identity=33.7078651685393, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=44.2748091603053, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787342, Length=265, Percent_Identity=31.6981132075472, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082439, Length=267, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=37.3239436619718, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17565396, Length=175, Percent_Identity=33.7142857142857, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17543026, Length=223, Percent_Identity=30.4932735426009, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=32.8671328671329, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI221330018, Length=296, Percent_Identity=32.4324324324324, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24586117, Length=265, Percent_Identity=32.4528301886792, Blast_Score=111, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30696; Mature: 30696

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDIGVNLTNASFASQRQAVLDRAYAAGVEQLVVTGTSVEGSEHALQLCHELDESAQR
CEEEEECCEECCCHHHHHHHHHHHHHHHHCHHHEEEECCCCCCHHHHHHHHHHHHHHHHH
LFCTAGIHPHSASDWTGDTEKQLHALLKENRVRAVGECGLDYNRDFSPRPKQEKVLEAHL
EEHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
AMAVELQLPVFLHERDANQRLLEILRDYRDRLPAAVVHCFTGERAALFSYLDLDLHIGIT
HHHHEEECCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHEEEEEECEE
GWICDERRGTHLHALVGNIPRGRLMLESDAPYLLPRSLRPKPKNGRNEPAYLPEVLREVA
EEEECCCCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRGETQEDLARHSTDCARQFFALPTLKKSTED
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQLIDIGVNLTNASFASQRQAVLDRAYAAGVEQLVVTGTSVEGSEHALQLCHELDESAQR
CEEEEECCEECCCHHHHHHHHHHHHHHHHCHHHEEEECCCCCCHHHHHHHHHHHHHHHHH
LFCTAGIHPHSASDWTGDTEKQLHALLKENRVRAVGECGLDYNRDFSPRPKQEKVLEAHL
EEHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
AMAVELQLPVFLHERDANQRLLEILRDYRDRLPAAVVHCFTGERAALFSYLDLDLHIGIT
HHHHEEECCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHEEEEEECEE
GWICDERRGTHLHALVGNIPRGRLMLESDAPYLLPRSLRPKPKNGRNEPAYLPEVLREVA
EEEECCCCCCCHHHHHCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRGETQEDLARHSTDCARQFFALPTLKKSTED
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]