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The map label for this gene is lasR [H]

Identifier: 66045285

GI number: 66045285

Start: 2389505

End: 2389768

Strand: Reverse

Name: lasR [H]

Synonym: Psyr_2045

Alternate gene names: 66045285

Gene position: 2389768-2389505 (Counterclockwise)

Preceding gene: 66045298

Following gene: 66045280

Centisome position: 39.22

GC content: 57.2

Gene sequence:

>264_bases
ATGCTTCGCGACAATGGAAAACCACCCGGCACCACGCCGCCTTCCCAAGTCACACCCGCCATCGTCCAGTTGACTGTCAA
GGAACGACAAGTCCTGGAATGGGTGGCGCTCGGCAAATCCGCCTGGGAAATATCACGGATACAAGGGTGCTCGGAAGCGA
CCGTGCACTTTCATACCAGCAATATCCGCCGCAAGTTCGGAGTGACGTCATTGAAGGCGGCGCTGGTGATGGCGATCAGG
CAGGGGGTTATTTTGGTGGAGTGA

Upstream 100 bases:

>100_bases
AAGGCCTTCACGGTCCTGCCGCGCTGTCATTTATGTCAGGTTCGCGTTAGGGGTTGCAGGGGTATCGTGGTGCGGCGATC
TTCAGGGAAAGGACTTCACC

Downstream 100 bases:

>100_bases
AGTATTTAAAAGCGGTGCACCCCACAGGAGATACTCCCCCTGCGTTGTGCACCTGGATTACGGATTAACACTTACATTTT
AGTTGTCTGGATTAAATCCA

Product: regulatory protein, LuxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MLRDNGKPPGTTPPSQVTPAIVQLTVKERQVLEWVALGKSAWEISRIQGCSEATVHFHTSNIRRKFGVTSLKAALVMAIR
QGVILVE

Sequences:

>Translated_87_residues
MLRDNGKPPGTTPPSQVTPAIVQLTVKERQVLEWVALGKSAWEISRIQGCSEATVHFHTSNIRRKFGVTSLKAALVMAIR
QGVILVE
>Mature_87_residues
MLRDNGKPPGTTPPSQVTPAIVQLTVKERQVLEWVALGKSAWEISRIQGCSEATVHFHTSNIRRKFGVTSLKAALVMAIR
QGVILVE

Specific function: Transcriptional activator of elastase structural gene (lasB). Binds to the PAI autoinducer [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 9550; Mature: 9550

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRDNGKPPGTTPPSQVTPAIVQLTVKERQVLEWVALGKSAWEISRIQGCSEATVHFHTS
CCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECC
NIRRKFGVTSLKAALVMAIRQGVILVE
HHHHHHCHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure
MLRDNGKPPGTTPPSQVTPAIVQLTVKERQVLEWVALGKSAWEISRIQGCSEATVHFHTS
CCCCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECC
NIRRKFGVTSLKAALVMAIRQGVILVE
HHHHHHCHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1902216; 7937080; 10984043 [H]