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The map label for this gene is etfA [H]

Identifier: 66045236

GI number: 66045236

Start: 2317972

End: 2318901

Strand: Direct

Name: etfA [H]

Synonym: Psyr_1996

Alternate gene names: 66045236

Gene position: 2317972-2318901 (Clockwise)

Preceding gene: 66045235

Following gene: 66045237

Centisome position: 38.04

GC content: 60.75

Gene sequence:

>930_bases
ATGACGATCCTGGTTATCGCTGAACACGACAACGCGACCGTAGCCCCGGCTACGCTCAACACCCTTGCTGCTGCCCAGAA
GATCGGCGGTGACATTCATTTGCTGGTGGCCGGTTCCGGCGTGAGCGCCGTTGCCGACGCCGCCGCCAAAATTGCCGGTG
TGACGAAGGTCCTGGTGGCTGACCACGAAGCCTACGCGCACCAACTGCCTGAAAACATCGCTCCCCTGGTTGTAGAGCTG
GCTGCGGGCCATAGCCATGTTCTGGCTGCGGCAACGTCCAATGGCAAGAACATCCTGCCGCGTGTCGCTGCGCAGCTGGA
TGTCGACCAGATCTCCGAGATCGTTTCGGTGGTGTCCGCCGACACCTTCACCCGTCCGATCTACGCCGGTAACGCCATCG
CCACCGTGCAGTCGACGGCTGCAGTCAAGGTCATCACCGTACGAGCCACCGGCTTCGATCCGGTGGCTGCAGAGGGTGGC
TCGGCCGCTGTTGAAGCGGTTTCGGCTGCTCACGATGCCGGCAAGTCCAGCTTTGTGGGTGAAGAACTGGCGAAATCCGA
TCGTCCGGAGCTGACAGCAGCGAAGATCGTCGTTTCCGGTGGTCGCGGCATGCAGAACGGCGACAACTTCAGGCACCTGT
ACACGCTGGCCGACAAGCTCGGTGCGGCAGTGGGTGCTTCCCGCGCTGCGGTCGACGCCGGTTTCGTACCCAACGACATG
CAGGTCGGTCAGACCGGCAAGATCGTTGCGCCTCAGTTGTATATCGCGGTCGGTATTTCCGGTGCGATTCAGCATCTGGC
CGGTATGAAGGATTCCAAGGTGATCGTTGCGATCAACAAGGATGAAGAGGCGCCAATCTTCCAGGTCGCCGATTACGGTC
TGGTGGCTGACTTGTTCGAAGCCATCCCCGAGCTGGAGAAGCTGGTTTAA

Upstream 100 bases:

>100_bases
CCTCAAGGTCGAAGCGCCGGCTGCACGCAGCGCCGGCATCAAGGTCAAGTCGGTGGCTGAACTGGTCGAGAAACTGAAAA
ACGAAGCGAAGGTAATCTAA

Downstream 100 bases:

>100_bases
GCCACGCGCTTGCACTATAAAGAGAACCCGTTCGATTCGGGGTTCGCGCACCGGCGGTTTACGGTGCGCCTGCCCGGATC
GAACGGGTTTTTTATTGAGT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTILVIAEHDNATVAPATLNTLAAAQKIGGDIHLLVAGSGVSAVADAAAKIAGVTKVLVADHEAYAHQLPENIAPLVVEL
AAGHSHVLAAATSNGKNILPRVAAQLDVDQISEIVSVVSADTFTRPIYAGNAIATVQSTAAVKVITVRATGFDPVAAEGG
SAAVEAVSAAHDAGKSSFVGEELAKSDRPELTAAKIVVSGGRGMQNGDNFRHLYTLADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPELEKLV

Sequences:

>Translated_309_residues
MTILVIAEHDNATVAPATLNTLAAAQKIGGDIHLLVAGSGVSAVADAAAKIAGVTKVLVADHEAYAHQLPENIAPLVVEL
AAGHSHVLAAATSNGKNILPRVAAQLDVDQISEIVSVVSADTFTRPIYAGNAIATVQSTAAVKVITVRATGFDPVAAEGG
SAAVEAVSAAHDAGKSSFVGEELAKSDRPELTAAKIVVSGGRGMQNGDNFRHLYTLADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPELEKLV
>Mature_308_residues
TILVIAEHDNATVAPATLNTLAAAQKIGGDIHLLVAGSGVSAVADAAAKIAGVTKVLVADHEAYAHQLPENIAPLVVELA
AGHSHVLAAATSNGKNILPRVAAQLDVDQISEIVSVVSADTFTRPIYAGNAIATVQSTAAVKVITVRATGFDPVAAEGGS
AAVEAVSAAHDAGKSSFVGEELAKSDRPELTAAKIVVSGGRGMQNGDNFRHLYTLADKLGAAVGASRAAVDAGFVPNDMQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAIPELEKLV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=310, Percent_Identity=60.3225806451613, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=62.0817843866171, Blast_Score=340, Evalue=1e-93,
Organism=Escherichia coli, GI1787990, Length=228, Percent_Identity=32.8947368421053, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786226, Length=227, Percent_Identity=33.0396475770925, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082157, Length=118, Percent_Identity=42.3728813559322, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=307, Percent_Identity=59.6091205211726, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6325261, Length=317, Percent_Identity=45.1104100946372, Blast_Score=253, Evalue=4e-68,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=64.4951140065147, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=64.4951140065147, Blast_Score=388, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31459; Mature: 31328

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNATVAPATLNTLAAAQKIGGDIHLLVAGSGVSAVADAAAKIAGVTKVLVA
CEEEEEEECCCCEECHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHEEEEE
DHEAYAHQLPENIAPLVVELAAGHSHVLAAATSNGKNILPRVAAQLDVDQISEIVSVVSA
CCHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHC
DTFTRPIYAGNAIATVQSTAAVKVITVRATGFDPVAAEGGSAAVEAVSAAHDAGKSSFVG
CHHCCCEECCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFRHLYTLADKLGAAVGASRAAVDAGFVPNDM
HHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AIPELEKLV
HHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNATVAPATLNTLAAAQKIGGDIHLLVAGSGVSAVADAAAKIAGVTKVLVA
EEEEEEECCCCEECHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHEEEEE
DHEAYAHQLPENIAPLVVELAAGHSHVLAAATSNGKNILPRVAAQLDVDQISEIVSVVSA
CCHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHC
DTFTRPIYAGNAIATVQSTAAVKVITVRATGFDPVAAEGGSAAVEAVSAAHDAGKSSFVG
CHHCCCEECCCEEEEEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
EELAKSDRPELTAAKIVVSGGRGMQNGDNFRHLYTLADKLGAAVGASRAAVDAGFVPNDM
HHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AIPELEKLV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]