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The map label for this gene is tycC [H]

Identifier: 66045199

GI number: 66045199

Start: 2252807

End: 2259271

Strand: Direct

Name: tycC [H]

Synonym: Psyr_1959

Alternate gene names: 66045199

Gene position: 2252807-2259271 (Clockwise)

Preceding gene: 66045198

Following gene: 66045200

Centisome position: 36.97

GC content: 62.6

Gene sequence:

>6465_bases
GTGCAACAGTTGCTTGACTCCGTTAAATCGCTGTCCGCCCGTGAACGCAAGGCGCTGGCGGTGCTGCTCAAGCGTCAAGG
GGTGAATCTCTACGGGGTCACGCCGATTGCCGTGAGGGAGACGCAGGCACCGTCCGCGCTCTCTTACGCGCAGCAGCGGC
AATGGATCATCTGGCAACTGGAGCCGCACAGCGCGGCCTACAACATTCCGCTGGCGCTGCGCCTGCACGGCGCGCTGAAT
GTCGAGGCATTGCGGCGCAGCGTGGAGCAATTGATCGAACGTCACGAAACCCTGCGCACGACCTTCGAACAGCAGGGCGA
TGAAGCGCAGCAGGTGGTGCACCCGGCGTCGCCGTTTGCGCTCGGTGCCGAGCAACTGGCGGCTGGCGAAACGGTCGAGC
GTTATGTGGATCAGGAAGTACAACGGCCTTTCGATCTGCAACACGGACCGCTGTTGCGCGTCAGGCTGCTCAGGCTGAGC
GCGCAGGAGCATGTACTGGTATTGACCCAGCACCACATCGTCTCCGATGGCTGGTCGATGCCGATCATGGTCGACGAACT
GATGCAGTGCTATCAGGCCGCCACGCTGGGCCGCGAGATCAAACTGGCGCCGTTGCCGATCCAGTACGCCGACTACGCCC
TCTGGCAGCGCAACTGGCTGGAAATGGGCGAGCAGGAACGCCAGCTGGCGTACTGGAAGCAGCAACTGGGCGAGCAACAG
CCGATTCTGGAATTGCCCACTGATCGGCCGCGTCCGGCACTGCGCAATTACGAAGGTGCGCGACTCAATGTCAAACTGGA
TGTCGCGCTGTTGAATAACCTCAAGACCCTGGCGCGCCAACAGGGCATCACCCTGTTCATGCTGTTGCTGGCCTCGTTTC
AGACCCTGCTGCATCGCTACAGCGGTCAGGCCGATATACGCGTAGGCGTGCCGGTCGCCAACCGTACCCGCAGCGAAACC
CAGGGGCTGATCGGCTTCTTCGTCAACACCCAGGTGCTCAAGGCCGAATTCACCACGCAGACCACCGTGGCCGGGCTGTT
GCAGCAGGTCAGACACACCGCCGTGCAGGCGCAGGCCCATCAGGACCTGCCGTTCGAACAACTGGTCGAAGCCTTGCAAC
CGCAGCGCGACCTGAGCCGCAGCCCGCTGTTTCAGGTGGCCTGCAACCACCAGAGCGAAGGCCACAACCAGAGCCGTGAG
CTGGCAGGGCTGCGTCTGGAATATCAGGTGTCCGACAAGCACACCGCGCAGTTCGACCTGACCCTTGACACCTGCGAACG
CCCGGACGGCCTGACAGCCGCACTGACCTACGCCACCGACCTGTTCGACGCATCGACCATCGAGCGCATGGCCAGCCACT
GGCGCAACCTGCTCAACGGCATGTGCCACGACGTCAATCAGCGTATCGCTGACCTGCCATTGCTGAGCGCCGAGGAACGC
CAGAACACCCTGCGTGACTGGAACCGCGATCTTGCGGTCTACCCAAGCGAGCACTGCGCGCATCAACGCATCGAAGCCCA
GGCCGAGCGTAACCCGCAGGCCATCGCCCTGAGCTTTGGCGATGAGCAACTGAGTTACCGGCAGCTCAACCAGCGTGCCA
ACCAACTGGCGCACAAACTGCGCGAACAGGGCGTCGGCCCGGATGTGCGCGTCGGGCTGGCCGCCGAGCGCGGTCTGGAG
ATGATTGTCGGTCTGCTGGCCATCCTCAAGGCAGGCGGCGCTTACGTGCCGCTGGACCCGGATTATCCGCAGGATCGCCT
GAGCTTTCTGATGCACGACAGCGGTATCGAACTGTTGCTGACCCAGGCGCATCTGCTTGAAAGGTTACCGATCCCTGCAC
AGGTTAAGAGCCACGATCTGGCTGACGCACTGGACGGCTACAGCACGGAAAACCCGCTCGACAAGACCGCGCCGGACAAC
CTGGCCTACGTGATCTACACCTCGGGTTCGACCGGCAAACCCAAAGGCACCTTGCTCGCCCATCACAACCTGATGCGCCT
GTTCGCGGCCACGGATGAGTGGTTCGAATTCAGCGAAAAGGACGTGTGGACGCTGTTCCATTCCTTCGCCTTCGACTTTT
CGGTGTGGGAGATTTTCGGCGCGCTGCTGCATGGCGGCCGACTGGTGATCGTGCCCCGCGAAGTGACCCGTTCGCCGGAA
GATTTCCATGCGCTGCTGGTCGAACAGCAGGTTACGGTGCTCAACCAGACGCCGTCGGCGTTCAAGCAACTGATGCACGT
GGCCTGTGATTCATCGCTACCGATGTCGCTGCAGACAGTCATCTTCGGCGGCGAGGCGCTGGACGTCGCCAGTCTGAAGC
CCTGGTTCGCGCGTTTCGGCGATCAATCACCGCAACTGATCAACATGTACGGCATCACCGAAACCACCGTGCATGTGAGC
TATCGACCGATCACGCTGGCCGACACGCAGAACCCGGCCAGCCCGATTGGCGAGGCGATTCCCGACCTGTCGTGGTACGT
GCTGGACGCTGATTTCAACCCGGTCGCCCAAGGTTGCAGCGGCGAGCTGCACATCGGCCATGCCGGTCTGGCGCGGGGTT
ATCACAATCGTGCGGCGCTGACTGCCGAACGTTTTGTTCCCGATCCGTTTTCCAGCGAGGGTGGCCGCCTGTATCGCACC
GGTGACCTGGCGCGTTATCGCGCGACAGGCGTGATCGACTACGTCGGGCGCATCGACCACCAGGTGAAGATTCGTGGCTT
CCGCATCGAACTGGGTGAAATCGAAGCGCGGCTGCAAGCGCACCCGGCCGTACGCGAAGTGAGCGTGCTGGCGCTGGACG
GGCAATTGGCAGCGTACCTGGTGCCTACTGAGCCTGATCAAGATCAGACAACCCTGCGTGAAGCGCTGAAAAGCCAACTC
AGGGCGCGCCTGCCGGATTACATGGTGCCCACCCATTTCATCGTCCTCGACAGCATGCCGCTGACCGCCAACGGCAAGCT
GGACCGCAAGGCGCTGCCTGCGCCGGACGCCAGTCAGTTGCAGGCCACCTACAGCGCGCCGCAGGGCGAGCTGGAGCAGC
AACTGGCAGCGATCTGGGCCGATCTGTTGAAACTCGAGCGGGTCGGGCGCAGCGACAACTTTTTCGAGCTGGGCGGGCAT
TCGCTGCTGGCCACTCAGGTGATTTCGCGCATTCGTCAGCAGCTGGATGTCGAGCTGTCGTTACGCGACCTGTTCGAAGC
GCGTGATCTGGCGGCCTTCGCGCTGGCAGCGGGCGCAGGGCAGGGCAACGGTGCGCCGCGCTTCATCAAGGCCGACCGCA
AGCAGCCGCTGGGTCTGTCCTACGCGCAGCAGCGTCAGTGGTTCCTCTGGCAGCTTGACCCGGAGAACACGGCGTACATT
ATTCCCGCAGCCCTGCGCCTGCGCGGTTCGCTGGACATCGCGGCACTGGAGCACAGTTTCAGCGCGCTGATCGCACGTCA
TGAAACCCTGCGCACGACCTTCCGCCAGCAGGGCGAGCATGCCGTACAGGTCATTCATGCGCCACGCGCCTTGACCCTGT
CGGTCGAGTCGGTGCCCAGCGGCCAGACCCTTGAAGCCTGCGTGCAGCAGGAAATGCATCGCCCGTTCGATCTGGAGCAA
GGGCCGCTGTTGCGAGTCCGTTTGCTGAACCTGAACACCGACGAGCATGTGCTGATTCTGACCCAGCATCACATTGTCTC
CGATGGTTGGTCGATGCCGATCATGGTCGATGAATTGGTGCGCCTTTACGAGGGTTACAGCCAGGGCCGTGCGGTGAGCT
TGACCGCGCTGGACCTGCAATACGCGGACTACGCGCTGTGGCAGCGGACCTGGATGGAGGCTGGCGAGCAGGCCCGGCAG
CTGGATTACTGGAAGCAGCAATTGGGCGATCAGCAGCCGATTCTGGAGCTGCCCGCCGATTACCCGCGGCCAGTGGTGCA
AAGCCATGCCGGTGCGCGGCTGGCAGTCGAGCTTGAGCCTGCGCTGATCGATGGCTTGAAGCAGGTCGCGCGGCAACAGG
GTGTGACCCTGTTCATGCTGTTGCTGGCGTCATTCCAGAGCCTGCTGCACCGTCACAGCGGTCAGTCGGACATTCGTGTC
GGCGTGCCGATTGCCAACCGCAACCGCGCTGAAACCGAAGGCCTGATCGGCTTCTTCGTCAACACGCAGGTGCTGCGTGC
CGAGTTTGACGTGCACACGACGTTCAACGAGTTGCTGCAGCAGGTCAAACACACCGCCCTGCAAGCCCAGGCGCATCAGG
AGCTGCCCTTCGAGCAACTGGTCGAAGCCCTGCAGCCCCAACGCAGCCTCAGCCACAGCCCGCTGTTTCAGGTGATGTTC
AATCACCAGAGCCAGGCCAGCGCCGATGTCCGCGCGCTGCCCGGTCTGCAGGTCGAGGCACTGCTGCCGGACAGTTACCC
GGCGCAGTTCGACCTGACCCTGAACACTGCTGAACATGACGGTGGCCTGAGCGCTGGCCTGACCTACGCGACAGCGTTGT
TCGACCCGCGCACCATCGAGCGCATGGCCGGGCACTGGCTGGCCTTGTTGCAGGCCATCTGCGCCAATGCCGCACAGCGG
ATCGCCGAAGTGCCGATGCTCGACAGGGCTGAACGGCAGCAGATTCTCCATGACTGGAACGCCACAGCCGCAGACTTCCC
CTGCGAAGACTGCCTGCACAGCCTGATCGAAGCCCAGGTACGCGCCACACCGCACGCGCCGGCGCTGATTTTCGCCGCCG
AGCAACTGAGCTACGCGCAACTCAACGCCCGCGCCAATCAGCTTGCGCATCGCCTGCGTGAGTCGGGCGTCGGCCCGGAC
GTGCTGGTTGGGATTTGCGTCGAGCGCAGCCTGGAACTGGTCATCGGTCTGCTGGCGATCATTAAAGCGGGCGGCGCTTA
TGTACCGCTGGACCCGGATTATCCCGAAGATCGGCTGGTTTACATGATGCAGGACAGCGGGATTGGCCTGCTGTTGACCC
AGACGGCGTTATTGGAGCGTTTGCCGATTCCGCCCCAGGTGCAGAGCCTGTGCCTGGATCCGCACGGCGACTGGCTGGAA
GGTTACAGCACTGCCAACCCGGTCAACCTGAGTCATCCATTGAATCTGGCTTACGTGATTTACACCTCGGGTTCGACCGG
CAAACCCAAGGGCGCGGGCAACAGCCATCGTGCGCTGGTCAACCGCTTGCACTGGATGCAGAAGGCCTACGGGCTGAACG
AATCCGACACCGTTTTGCAGAAAACGCCGTTCAGTTTCGACGTGTCGGTCTGGGAATTCTTCTGGCCGCTGATGACCGGC
GCACGCCTGGCCGTGGCGCTGCCGGGTGATCATCGCGACCCCGAGCGGCTGGTGCAGACCATCCGTGAGCATCAGGTCAC
GACTTTGCATTTCGTGCCGTCGATGCTGCAGGCGTTCATGACTCATCCGCAGGTGGAAAGCTGTAACACGCTGCGTCGGG
TCGTATGCAGCGGTGAAGCACTGCCTGCCGAACTGGCCGCCCAGGTGCTCAAGCGTCTGCCGCTGGCCGGTCTGTACAAC
CTGTATGGCCCCACCGAAGCGGCCATCGACGTTACCCATTGGACGTGCAGCACGGATGACATCCTCAGCGTGCCGATCGG
GCGGCCGATCGACAACCTGAAAACCCACATCCTCGACGATGGCCTGCTGCCTGCCGCACAGGGCGTGGCGGCGGAGTTGT
ATCTGGGTGGCGTTGGTCTGGCACGCGGTTATCACAACCGTGCAGCGCTGACGGCTGAGCGCTTCGTGCCGGATCCGTTC
GGCGAACAGGGCGGCGGCAGGCTGTACCGCACCGGTGATCTGGCGCGTTATCGCGACGCGGGCGTCATCGATTACGCCGG
GCGTATCGACCATCAGGTGAAGATTCGCGGCTTGCGCATCGAACTGGGCGAAATCGAAGCCAGCCTGCTGGAGCACGACA
GCGTTCATGAGGCGGTGGTGATCGACGTTGACGGCCCGTCCGGCAAGCAGCTGGCGGCGTATCTGGTGGTCGAGCACCAT
GACGATCAGTTGCGTGATGCGCTCAAGGCCTTCCTCAAGGAATCGCTGCCGGATTACATGGTGCCCACGCATTTCATCGT
GCTGGACAGAATGCCGCTGAGCGCCAACGGCAAGCTCGATCGCAAGGCCCTGCCGAAACCGGACGCCAGCCAGTTGCAGC
GCCAGTACGTCGCACCGTCCACAGAGCAGGAACAGCAGATGGCGGCGATCTGGGCCGAGGTGCTGAAGGTCGAGCGTGTC
GGCCTGAGCGACGATTTCTTCGAGCTCGGTGGCCACTCGCTGCTGGCGACGCAGCTGATTTCCAGAATCCACAGCGGCCT
GGGAATCGACATTCCGCTGCGCCTGATCTTCGAGAAACCGCAATTGAACGAATTTATTCAGGCCTTCGCCGACAGTGGCC
TGTCGCTGACCGAGGACGGCTTGTCCGATATTGAAAAAATGATGAATGAAATGGCGGGTATCTGA

Upstream 100 bases:

>100_bases
GTGACCACGCGCAGGACGAATTGACTAAATCACTGGAGGCACTCAAACGTTTATCAGCGGAGGAAATTGATAATTTGATT
GCTTAGCAGGAGAGACCCCA

Downstream 100 bases:

>100_bases
CATGGACAAGTCTGCAGCAGAGCGTATCGCCCAGCGTTTCGTCGGCTTGCCCGTCGAACAGCGCCGGCAGATCCTCGCCA
AGATGCACGAGACCGGACAG

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2154; Mature: 2154

Protein sequence:

>2154_residues
MQQLLDSVKSLSARERKALAVLLKRQGVNLYGVTPIAVRETQAPSALSYAQQRQWIIWQLEPHSAAYNIPLALRLHGALN
VEALRRSVEQLIERHETLRTTFEQQGDEAQQVVHPASPFALGAEQLAAGETVERYVDQEVQRPFDLQHGPLLRVRLLRLS
AQEHVLVLTQHHIVSDGWSMPIMVDELMQCYQAATLGREIKLAPLPIQYADYALWQRNWLEMGEQERQLAYWKQQLGEQQ
PILELPTDRPRPALRNYEGARLNVKLDVALLNNLKTLARQQGITLFMLLLASFQTLLHRYSGQADIRVGVPVANRTRSET
QGLIGFFVNTQVLKAEFTTQTTVAGLLQQVRHTAVQAQAHQDLPFEQLVEALQPQRDLSRSPLFQVACNHQSEGHNQSRE
LAGLRLEYQVSDKHTAQFDLTLDTCERPDGLTAALTYATDLFDASTIERMASHWRNLLNGMCHDVNQRIADLPLLSAEER
QNTLRDWNRDLAVYPSEHCAHQRIEAQAERNPQAIALSFGDEQLSYRQLNQRANQLAHKLREQGVGPDVRVGLAAERGLE
MIVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLLTQAHLLERLPIPAQVKSHDLADALDGYSTENPLDKTAPDN
LAYVIYTSGSTGKPKGTLLAHHNLMRLFAATDEWFEFSEKDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPE
DFHALLVEQQVTVLNQTPSAFKQLMHVACDSSLPMSLQTVIFGGEALDVASLKPWFARFGDQSPQLINMYGITETTVHVS
YRPITLADTQNPASPIGEAIPDLSWYVLDADFNPVAQGCSGELHIGHAGLARGYHNRAALTAERFVPDPFSSEGGRLYRT
GDLARYRATGVIDYVGRIDHQVKIRGFRIELGEIEARLQAHPAVREVSVLALDGQLAAYLVPTEPDQDQTTLREALKSQL
RARLPDYMVPTHFIVLDSMPLTANGKLDRKALPAPDASQLQATYSAPQGELEQQLAAIWADLLKLERVGRSDNFFELGGH
SLLATQVISRIRQQLDVELSLRDLFEARDLAAFALAAGAGQGNGAPRFIKADRKQPLGLSYAQQRQWFLWQLDPENTAYI
IPAALRLRGSLDIAALEHSFSALIARHETLRTTFRQQGEHAVQVIHAPRALTLSVESVPSGQTLEACVQQEMHRPFDLEQ
GPLLRVRLLNLNTDEHVLILTQHHIVSDGWSMPIMVDELVRLYEGYSQGRAVSLTALDLQYADYALWQRTWMEAGEQARQ
LDYWKQQLGDQQPILELPADYPRPVVQSHAGARLAVELEPALIDGLKQVARQQGVTLFMLLLASFQSLLHRHSGQSDIRV
GVPIANRNRAETEGLIGFFVNTQVLRAEFDVHTTFNELLQQVKHTALQAQAHQELPFEQLVEALQPQRSLSHSPLFQVMF
NHQSQASADVRALPGLQVEALLPDSYPAQFDLTLNTAEHDGGLSAGLTYATALFDPRTIERMAGHWLALLQAICANAAQR
IAEVPMLDRAERQQILHDWNATAADFPCEDCLHSLIEAQVRATPHAPALIFAAEQLSYAQLNARANQLAHRLRESGVGPD
VLVGICVERSLELVIGLLAIIKAGGAYVPLDPDYPEDRLVYMMQDSGIGLLLTQTALLERLPIPPQVQSLCLDPHGDWLE
GYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYGLNESDTVLQKTPFSFDVSVWEFFWPLMTG
ARLAVALPGDHRDPERLVQTIREHQVTTLHFVPSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLYN
LYGPTEAAIDVTHWTCSTDDILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPF
GEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEASLLEHDSVHEAVVIDVDGPSGKQLAAYLVVEHH
DDQLRDALKAFLKESLPDYMVPTHFIVLDRMPLSANGKLDRKALPKPDASQLQRQYVAPSTEQEQQMAAIWAEVLKVERV
GLSDDFFELGGHSLLATQLISRIHSGLGIDIPLRLIFEKPQLNEFIQAFADSGLSLTEDGLSDIEKMMNEMAGI

Sequences:

>Translated_2154_residues
MQQLLDSVKSLSARERKALAVLLKRQGVNLYGVTPIAVRETQAPSALSYAQQRQWIIWQLEPHSAAYNIPLALRLHGALN
VEALRRSVEQLIERHETLRTTFEQQGDEAQQVVHPASPFALGAEQLAAGETVERYVDQEVQRPFDLQHGPLLRVRLLRLS
AQEHVLVLTQHHIVSDGWSMPIMVDELMQCYQAATLGREIKLAPLPIQYADYALWQRNWLEMGEQERQLAYWKQQLGEQQ
PILELPTDRPRPALRNYEGARLNVKLDVALLNNLKTLARQQGITLFMLLLASFQTLLHRYSGQADIRVGVPVANRTRSET
QGLIGFFVNTQVLKAEFTTQTTVAGLLQQVRHTAVQAQAHQDLPFEQLVEALQPQRDLSRSPLFQVACNHQSEGHNQSRE
LAGLRLEYQVSDKHTAQFDLTLDTCERPDGLTAALTYATDLFDASTIERMASHWRNLLNGMCHDVNQRIADLPLLSAEER
QNTLRDWNRDLAVYPSEHCAHQRIEAQAERNPQAIALSFGDEQLSYRQLNQRANQLAHKLREQGVGPDVRVGLAAERGLE
MIVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLLTQAHLLERLPIPAQVKSHDLADALDGYSTENPLDKTAPDN
LAYVIYTSGSTGKPKGTLLAHHNLMRLFAATDEWFEFSEKDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPE
DFHALLVEQQVTVLNQTPSAFKQLMHVACDSSLPMSLQTVIFGGEALDVASLKPWFARFGDQSPQLINMYGITETTVHVS
YRPITLADTQNPASPIGEAIPDLSWYVLDADFNPVAQGCSGELHIGHAGLARGYHNRAALTAERFVPDPFSSEGGRLYRT
GDLARYRATGVIDYVGRIDHQVKIRGFRIELGEIEARLQAHPAVREVSVLALDGQLAAYLVPTEPDQDQTTLREALKSQL
RARLPDYMVPTHFIVLDSMPLTANGKLDRKALPAPDASQLQATYSAPQGELEQQLAAIWADLLKLERVGRSDNFFELGGH
SLLATQVISRIRQQLDVELSLRDLFEARDLAAFALAAGAGQGNGAPRFIKADRKQPLGLSYAQQRQWFLWQLDPENTAYI
IPAALRLRGSLDIAALEHSFSALIARHETLRTTFRQQGEHAVQVIHAPRALTLSVESVPSGQTLEACVQQEMHRPFDLEQ
GPLLRVRLLNLNTDEHVLILTQHHIVSDGWSMPIMVDELVRLYEGYSQGRAVSLTALDLQYADYALWQRTWMEAGEQARQ
LDYWKQQLGDQQPILELPADYPRPVVQSHAGARLAVELEPALIDGLKQVARQQGVTLFMLLLASFQSLLHRHSGQSDIRV
GVPIANRNRAETEGLIGFFVNTQVLRAEFDVHTTFNELLQQVKHTALQAQAHQELPFEQLVEALQPQRSLSHSPLFQVMF
NHQSQASADVRALPGLQVEALLPDSYPAQFDLTLNTAEHDGGLSAGLTYATALFDPRTIERMAGHWLALLQAICANAAQR
IAEVPMLDRAERQQILHDWNATAADFPCEDCLHSLIEAQVRATPHAPALIFAAEQLSYAQLNARANQLAHRLRESGVGPD
VLVGICVERSLELVIGLLAIIKAGGAYVPLDPDYPEDRLVYMMQDSGIGLLLTQTALLERLPIPPQVQSLCLDPHGDWLE
GYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYGLNESDTVLQKTPFSFDVSVWEFFWPLMTG
ARLAVALPGDHRDPERLVQTIREHQVTTLHFVPSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLYN
LYGPTEAAIDVTHWTCSTDDILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPF
GEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEASLLEHDSVHEAVVIDVDGPSGKQLAAYLVVEHH
DDQLRDALKAFLKESLPDYMVPTHFIVLDRMPLSANGKLDRKALPKPDASQLQRQYVAPSTEQEQQMAAIWAEVLKVERV
GLSDDFFELGGHSLLATQLISRIHSGLGIDIPLRLIFEKPQLNEFIQAFADSGLSLTEDGLSDIEKMMNEMAGI
>Mature_2154_residues
MQQLLDSVKSLSARERKALAVLLKRQGVNLYGVTPIAVRETQAPSALSYAQQRQWIIWQLEPHSAAYNIPLALRLHGALN
VEALRRSVEQLIERHETLRTTFEQQGDEAQQVVHPASPFALGAEQLAAGETVERYVDQEVQRPFDLQHGPLLRVRLLRLS
AQEHVLVLTQHHIVSDGWSMPIMVDELMQCYQAATLGREIKLAPLPIQYADYALWQRNWLEMGEQERQLAYWKQQLGEQQ
PILELPTDRPRPALRNYEGARLNVKLDVALLNNLKTLARQQGITLFMLLLASFQTLLHRYSGQADIRVGVPVANRTRSET
QGLIGFFVNTQVLKAEFTTQTTVAGLLQQVRHTAVQAQAHQDLPFEQLVEALQPQRDLSRSPLFQVACNHQSEGHNQSRE
LAGLRLEYQVSDKHTAQFDLTLDTCERPDGLTAALTYATDLFDASTIERMASHWRNLLNGMCHDVNQRIADLPLLSAEER
QNTLRDWNRDLAVYPSEHCAHQRIEAQAERNPQAIALSFGDEQLSYRQLNQRANQLAHKLREQGVGPDVRVGLAAERGLE
MIVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLLTQAHLLERLPIPAQVKSHDLADALDGYSTENPLDKTAPDN
LAYVIYTSGSTGKPKGTLLAHHNLMRLFAATDEWFEFSEKDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPE
DFHALLVEQQVTVLNQTPSAFKQLMHVACDSSLPMSLQTVIFGGEALDVASLKPWFARFGDQSPQLINMYGITETTVHVS
YRPITLADTQNPASPIGEAIPDLSWYVLDADFNPVAQGCSGELHIGHAGLARGYHNRAALTAERFVPDPFSSEGGRLYRT
GDLARYRATGVIDYVGRIDHQVKIRGFRIELGEIEARLQAHPAVREVSVLALDGQLAAYLVPTEPDQDQTTLREALKSQL
RARLPDYMVPTHFIVLDSMPLTANGKLDRKALPAPDASQLQATYSAPQGELEQQLAAIWADLLKLERVGRSDNFFELGGH
SLLATQVISRIRQQLDVELSLRDLFEARDLAAFALAAGAGQGNGAPRFIKADRKQPLGLSYAQQRQWFLWQLDPENTAYI
IPAALRLRGSLDIAALEHSFSALIARHETLRTTFRQQGEHAVQVIHAPRALTLSVESVPSGQTLEACVQQEMHRPFDLEQ
GPLLRVRLLNLNTDEHVLILTQHHIVSDGWSMPIMVDELVRLYEGYSQGRAVSLTALDLQYADYALWQRTWMEAGEQARQ
LDYWKQQLGDQQPILELPADYPRPVVQSHAGARLAVELEPALIDGLKQVARQQGVTLFMLLLASFQSLLHRHSGQSDIRV
GVPIANRNRAETEGLIGFFVNTQVLRAEFDVHTTFNELLQQVKHTALQAQAHQELPFEQLVEALQPQRSLSHSPLFQVMF
NHQSQASADVRALPGLQVEALLPDSYPAQFDLTLNTAEHDGGLSAGLTYATALFDPRTIERMAGHWLALLQAICANAAQR
IAEVPMLDRAERQQILHDWNATAADFPCEDCLHSLIEAQVRATPHAPALIFAAEQLSYAQLNARANQLAHRLRESGVGPD
VLVGICVERSLELVIGLLAIIKAGGAYVPLDPDYPEDRLVYMMQDSGIGLLLTQTALLERLPIPPQVQSLCLDPHGDWLE
GYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYGLNESDTVLQKTPFSFDVSVWEFFWPLMTG
ARLAVALPGDHRDPERLVQTIREHQVTTLHFVPSMLQAFMTHPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLYN
LYGPTEAAIDVTHWTCSTDDILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPF
GEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEASLLEHDSVHEAVVIDVDGPSGKQLAAYLVVEHH
DDQLRDALKAFLKESLPDYMVPTHFIVLDRMPLSANGKLDRKALPKPDASQLQRQYVAPSTEQEQQMAAIWAEVLKVERV
GLSDDFFELGGHSLLATQLISRIHSGLGIDIPLRLIFEKPQLNEFIQAFADSGLSLTEDGLSDIEKMMNEMAGI

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=587, Percent_Identity=25.0425894378194, Blast_Score=136, Evalue=3e-31,
Organism=Homo sapiens, GI187761345, Length=555, Percent_Identity=25.045045045045, Blast_Score=103, Evalue=2e-21,
Organism=Homo sapiens, GI187761343, Length=555, Percent_Identity=25.045045045045, Blast_Score=103, Evalue=2e-21,
Organism=Homo sapiens, GI156151445, Length=549, Percent_Identity=23.4972677595628, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI28416953, Length=561, Percent_Identity=24.2424242424242, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI38505220, Length=500, Percent_Identity=23, Blast_Score=92, Evalue=8e-18,
Organism=Homo sapiens, GI115511026, Length=382, Percent_Identity=25.130890052356, Blast_Score=89, Evalue=5e-17,
Organism=Homo sapiens, GI42544132, Length=511, Percent_Identity=21.9178082191781, Blast_Score=80, Evalue=3e-14,
Organism=Homo sapiens, GI13375727, Length=409, Percent_Identity=22.0048899755501, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI122937307, Length=377, Percent_Identity=23.6074270557029, Blast_Score=75, Evalue=8e-13,
Organism=Escherichia coli, GI1786801, Length=1041, Percent_Identity=35.3506243996158, Blast_Score=466, Evalue=1e-131,
Organism=Escherichia coli, GI145693145, Length=524, Percent_Identity=24.236641221374, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1786810, Length=515, Percent_Identity=26.7961165048544, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1788107, Length=526, Percent_Identity=25.4752851711027, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI1790505, Length=607, Percent_Identity=23.5584843492586, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI221142682, Length=505, Percent_Identity=24.1584158415842, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1788595, Length=493, Percent_Identity=25.1521298174442, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=1139, Percent_Identity=22.739244951712, Blast_Score=219, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17556356, Length=1247, Percent_Identity=23.897353648757, Blast_Score=161, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI32564422, Length=518, Percent_Identity=25.0965250965251, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32564420, Length=518, Percent_Identity=25.0965250965251, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538037, Length=527, Percent_Identity=25.0474383301708, Blast_Score=99, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994703, Length=364, Percent_Identity=24.4505494505494, Blast_Score=95, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994694, Length=364, Percent_Identity=24.4505494505494, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17558820, Length=523, Percent_Identity=23.9005736137667, Blast_Score=94, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994690, Length=364, Percent_Identity=24.4505494505494, Blast_Score=94, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17557194, Length=533, Percent_Identity=24.202626641651, Blast_Score=93, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=529, Percent_Identity=22.6843100189036, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983001, Length=434, Percent_Identity=26.2672811059908, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982997, Length=434, Percent_Identity=26.2672811059908, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560140, Length=362, Percent_Identity=23.4806629834254, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531443, Length=540, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985884, Length=390, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71996755, Length=504, Percent_Identity=20.8333333333333, Blast_Score=70, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=913, Percent_Identity=25.5202628696605, Blast_Score=249, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6319264, Length=563, Percent_Identity=22.9129662522202, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319699, Length=485, Percent_Identity=21.6494845360825, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24648676, Length=637, Percent_Identity=31.2401883830455, Blast_Score=249, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24581924, Length=542, Percent_Identity=24.169741697417, Blast_Score=117, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24582852, Length=579, Percent_Identity=22.9706390328152, Blast_Score=97, Evalue=2e-19,
Organism=Drosophila melanogaster, GI62472339, Length=539, Percent_Identity=23.9332096474954, Blast_Score=95, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667955, Length=539, Percent_Identity=23.9332096474954, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI18859661, Length=515, Percent_Identity=24.2718446601942, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667959, Length=373, Percent_Identity=25.7372654155496, Blast_Score=86, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355181, Length=495, Percent_Identity=22.4242424242424, Blast_Score=73, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 239952; Mature: 239952

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLLDSVKSLSARERKALAVLLKRQGVNLYGVTPIAVRETQAPSALSYAQQRQWIIWQL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCHHHHHHHCCCEEEEEE
EPHSAAYNIPLALRLHGALNVEALRRSVEQLIERHETLRTTFEQQGDEAQQVVHPASPFA
CCCCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
LGAEQLAAGETVERYVDQEVQRPFDLQHGPLLRVRLLRLSAQEHVLVLTQHHIVSDGWSM
CCHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEECCCCCC
PIMVDELMQCYQAATLGREIKLAPLPIQYADYALWQRNWLEMGEQERQLAYWKQQLGEQQ
CHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
PILELPTDRPRPALRNYEGARLNVKLDVALLNNLKTLARQQGITLFMLLLASFQTLLHRY
CCEECCCCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SGQADIRVGVPVANRTRSETQGLIGFFVNTQVLKAEFTTQTTVAGLLQQVRHTAVQAQAH
CCCCEEEECCCCCCCCCHHHCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QDLPFEQLVEALQPQRDLSRSPLFQVACNHQSEGHNQSRELAGLRLEYQVSDKHTAQFDL
CCCCHHHHHHHHCCHHCCCCCCCEEEEECCCCCCCCCHHHHHCEEEEEEECCCCCEEEEE
TLDTCERPDGLTAALTYATDLFDASTIERMASHWRNLLNGMCHDVNQRIADLPLLSAEER
EECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QNTLRDWNRDLAVYPSEHCAHQRIEAQAERNPQAIALSFGDEQLSYRQLNQRANQLAHKL
HHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
REQGVGPDVRVGLAAERGLEMIVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLL
HHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCCCHHHHH
TQAHLLERLPIPAQVKSHDLADALDGYSTENPLDKTAPDNLAYVIYTSGSTGKPKGTLLA
HHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEH
HHNLMRLFAATDEWFEFSEKDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPE
HHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCH
DFHALLVEQQVTVLNQTPSAFKQLMHVACDSSLPMSLQTVIFGGEALDVASLKPWFARFG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCEECHHHCCHHHHHCC
DQSPQLINMYGITETTVHVSYRPITLADTQNPASPIGEAIPDLSWYVLDADFNPVAQGCS
CCCCCEEEEECCEEEEEEEEEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCHHHCCCC
GELHIGHAGLARGYHNRAALTAERFVPDPFSSEGGRLYRTGDLARYRATGVIDYVGRIDH
CCEEECCHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCC
QVKIRGFRIELGEIEARLQAHPAVREVSVLALDGQLAAYLVPTEPDQDQTTLREALKSQL
EEEEEEEEEEHHHHHHHHHCCCCHHEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
RARLPDYMVPTHFIVLDSMPLTANGKLDRKALPAPDASQLQATYSAPQGELEQQLAAIWA
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
DLLKLERVGRSDNFFELGGHSLLATQVISRIRQQLDVELSLRDLFEARDLAAFALAAGAG
HHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCC
QGNGAPRFIKADRKQPLGLSYAQQRQWFLWQLDPENTAYIIPAALRLRGSLDIAALEHSF
CCCCCCCEEECCCCCCCCCCHHHCCCEEEEEECCCCCEEEEEHHHHHCCCCCHHHHHHHH
SALIARHETLRTTFRQQGEHAVQVIHAPRALTLSVESVPSGQTLEACVQQEMHRPFDLEQ
HHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GPLLRVRLLNLNTDEHVLILTQHHIVSDGWSMPIMVDELVRLYEGYSQGRAVSLTALDLQ
CCEEEEEEEECCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHH
YADYALWQRTWMEAGEQARQLDYWKQQLGDQQPILELPADYPRPVVQSHAGARLAVELEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHCCCCCEEEEEECH
ALIDGLKQVARQQGVTLFMLLLASFQSLLHRHSGQSDIRVGVPIANRNRAETEGLIGFFV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCCCCCCCCEEEEEE
NTQVLRAEFDVHTTFNELLQQVKHTALQAQAHQELPFEQLVEALQPQRSLSHSPLFQVMF
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHCCCCCCHHHHHH
NHQSQASADVRALPGLQVEALLPDSYPAQFDLTLNTAEHDGGLSAGLTYATALFDPRTIE
CCCCCCCCCHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHH
RMAGHWLALLQAICANAAQRIAEVPMLDRAERQQILHDWNATAADFPCEDCLHSLIEAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RATPHAPALIFAAEQLSYAQLNARANQLAHRLRESGVGPDVLVGICVERSLELVIGLLAI
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IKAGGAYVPLDPDYPEDRLVYMMQDSGIGLLLTQTALLERLPIPPQVQSLCLDPHGDWLE
HHCCCCEECCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCHHC
GYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYGLNESDTVLQ
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHC
KTPFSFDVSVWEFFWPLMTGARLAVALPGDHRDPERLVQTIREHQVTTLHFVPSMLQAFM
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
THPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLYNLYGPTEAAIDVTHWTCSTDD
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEEEEEECCCCC
ILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPF
EEECCCCCCHHHHHHHHHCCCCCCHHCCCCHHHEECCHHHHCCCCCHHHHHHHHCCCCCC
GEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEASLLEHDSVHEAVV
CCCCCCEEEECCCCHHHCCCCCEEECCCCCCEEEEEEEEEEHHHHHHHHHHCCCCCCEEE
IDVDGPSGKQLAAYLVVEHHDDQLRDALKAFLKESLPDYMVPTHFIVLDRMPLSANGKLD
EEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
RKALPKPDASQLQRQYVAPSTEQEQQMAAIWAEVLKVERVGLSDDFFELGGHSLLATQLI
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHH
SRIHSGLGIDIPLRLIFEKPQLNEFIQAFADSGLSLTEDGLSDIEKMMNEMAGI
HHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQLLDSVKSLSARERKALAVLLKRQGVNLYGVTPIAVRETQAPSALSYAQQRQWIIWQL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCHHHHHHHCCCEEEEEE
EPHSAAYNIPLALRLHGALNVEALRRSVEQLIERHETLRTTFEQQGDEAQQVVHPASPFA
CCCCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
LGAEQLAAGETVERYVDQEVQRPFDLQHGPLLRVRLLRLSAQEHVLVLTQHHIVSDGWSM
CCHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEECCCCCC
PIMVDELMQCYQAATLGREIKLAPLPIQYADYALWQRNWLEMGEQERQLAYWKQQLGEQQ
CHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
PILELPTDRPRPALRNYEGARLNVKLDVALLNNLKTLARQQGITLFMLLLASFQTLLHRY
CCEECCCCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SGQADIRVGVPVANRTRSETQGLIGFFVNTQVLKAEFTTQTTVAGLLQQVRHTAVQAQAH
CCCCEEEECCCCCCCCCHHHCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QDLPFEQLVEALQPQRDLSRSPLFQVACNHQSEGHNQSRELAGLRLEYQVSDKHTAQFDL
CCCCHHHHHHHHCCHHCCCCCCCEEEEECCCCCCCCCHHHHHCEEEEEEECCCCCEEEEE
TLDTCERPDGLTAALTYATDLFDASTIERMASHWRNLLNGMCHDVNQRIADLPLLSAEER
EECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QNTLRDWNRDLAVYPSEHCAHQRIEAQAERNPQAIALSFGDEQLSYRQLNQRANQLAHKL
HHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
REQGVGPDVRVGLAAERGLEMIVGLLAILKAGGAYVPLDPDYPQDRLSFLMHDSGIELLL
HHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCCCHHHHH
TQAHLLERLPIPAQVKSHDLADALDGYSTENPLDKTAPDNLAYVIYTSGSTGKPKGTLLA
HHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEH
HHNLMRLFAATDEWFEFSEKDVWTLFHSFAFDFSVWEIFGALLHGGRLVIVPREVTRSPE
HHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCH
DFHALLVEQQVTVLNQTPSAFKQLMHVACDSSLPMSLQTVIFGGEALDVASLKPWFARFG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCEECHHHCCHHHHHCC
DQSPQLINMYGITETTVHVSYRPITLADTQNPASPIGEAIPDLSWYVLDADFNPVAQGCS
CCCCCEEEEECCEEEEEEEEEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCHHHCCCC
GELHIGHAGLARGYHNRAALTAERFVPDPFSSEGGRLYRTGDLARYRATGVIDYVGRIDH
CCEEECCHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCC
QVKIRGFRIELGEIEARLQAHPAVREVSVLALDGQLAAYLVPTEPDQDQTTLREALKSQL
EEEEEEEEEEHHHHHHHHHCCCCHHEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
RARLPDYMVPTHFIVLDSMPLTANGKLDRKALPAPDASQLQATYSAPQGELEQQLAAIWA
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
DLLKLERVGRSDNFFELGGHSLLATQVISRIRQQLDVELSLRDLFEARDLAAFALAAGAG
HHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCC
QGNGAPRFIKADRKQPLGLSYAQQRQWFLWQLDPENTAYIIPAALRLRGSLDIAALEHSF
CCCCCCCEEECCCCCCCCCCHHHCCCEEEEEECCCCCEEEEEHHHHHCCCCCHHHHHHHH
SALIARHETLRTTFRQQGEHAVQVIHAPRALTLSVESVPSGQTLEACVQQEMHRPFDLEQ
HHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GPLLRVRLLNLNTDEHVLILTQHHIVSDGWSMPIMVDELVRLYEGYSQGRAVSLTALDLQ
CCEEEEEEEECCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHH
YADYALWQRTWMEAGEQARQLDYWKQQLGDQQPILELPADYPRPVVQSHAGARLAVELEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHCCCCCEEEEEECH
ALIDGLKQVARQQGVTLFMLLLASFQSLLHRHSGQSDIRVGVPIANRNRAETEGLIGFFV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCCCCCCCCEEEEEE
NTQVLRAEFDVHTTFNELLQQVKHTALQAQAHQELPFEQLVEALQPQRSLSHSPLFQVMF
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHCCCCCCHHHHHH
NHQSQASADVRALPGLQVEALLPDSYPAQFDLTLNTAEHDGGLSAGLTYATALFDPRTIE
CCCCCCCCCHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHH
RMAGHWLALLQAICANAAQRIAEVPMLDRAERQQILHDWNATAADFPCEDCLHSLIEAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RATPHAPALIFAAEQLSYAQLNARANQLAHRLRESGVGPDVLVGICVERSLELVIGLLAI
HCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IKAGGAYVPLDPDYPEDRLVYMMQDSGIGLLLTQTALLERLPIPPQVQSLCLDPHGDWLE
HHCCCCEECCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCHHC
GYSTANPVNLSHPLNLAYVIYTSGSTGKPKGAGNSHRALVNRLHWMQKAYGLNESDTVLQ
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHC
KTPFSFDVSVWEFFWPLMTGARLAVALPGDHRDPERLVQTIREHQVTTLHFVPSMLQAFM
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
THPQVESCNTLRRVVCSGEALPAELAAQVLKRLPLAGLYNLYGPTEAAIDVTHWTCSTDD
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEEEEEECCCCC
ILSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPF
EEECCCCCCHHHHHHHHHCCCCCCHHCCCCHHHEECCHHHHCCCCCHHHHHHHHCCCCCC
GEQGGGRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEASLLEHDSVHEAVV
CCCCCCEEEECCCCHHHCCCCCEEECCCCCCEEEEEEEEEEHHHHHHHHHHCCCCCCEEE
IDVDGPSGKQLAAYLVVEHHDDQLRDALKAFLKESLPDYMVPTHFIVLDRMPLSANGKLD
EEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
RKALPKPDASQLQRQYVAPSTEQEQQMAAIWAEVLKVERVGLSDDFFELGGHSLLATQLI
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHH
SRIHSGLGIDIPLRLIFEKPQLNEFIQAFADSGLSLTEDGLSDIEKMMNEMAGI
HHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]