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The map label for this gene is luxQ [H]

Identifier: 66045179

GI number: 66045179

Start: 2211083

End: 2213422

Strand: Reverse

Name: luxQ [H]

Synonym: Psyr_1939

Alternate gene names: 66045179

Gene position: 2213422-2211083 (Counterclockwise)

Preceding gene: 66045180

Following gene: 66045178

Centisome position: 36.32

GC content: 61.5

Gene sequence:

>2340_bases
ATGACGGCACACGCCAGCAGTCGCTGGGAAGGCCTACCGCTACGCGGCAAGGCACTGGTGGCCATTTCGCTGCCACTGGC
GATTCTGATGTTCTCGCTGGTGCTGATTTATATCGCCGAGCGCCAGACCGCTCGGGCAGAGGAAGACGTACGGCGTGTGC
TGCTCGTCCAAGGCGATATCCAGACCCTTCACACCCAGATCGCAGAAGGTGCGGCCAGCGTGCGTGGCTACCTGCTGACC
CACCAGGAAGACTTCCTGCCCGGCTATCTCAACGCGCAACCGCTGATCGAGGCGGCGCTGGCCCGGCTCAACACCAATGT
GCGTGACGAGCAGATGCGCGAACACCTGAAAGCCATCGAGCCGCTGATCAACACCAAGGTCGAAGGCCTGGAAAAACTGC
GCTCGATGAATCGGGAGGACCGGGAAACCGTCGCCCGCATCCTGATCGAAAACAAGTACGTACTCGACCAGTTGCGCGAA
CGCATCGGCATCATGCGCGAACGTGAAGACGCGCTGCTTGCCGAACGCACCGAGGCTGCCGCAGCCACCCGCGAGCGCCT
GCTGCTGTCGACCCTGCTGGCAGCGGCCTGCGGAATCTTCGGGGCCATTCTTGCCGTGCTGATGCTGTCCAAAGGCATCG
TCGCCAGGGTGCATCAGGTGCAACGCAACGCCCAGCGTCTGGCGCTGGGACATCCGCTGCTGCCCCAGCCGCCTGAAAAG
GACGAAATCGGCCAGCTCGGCACCCGGCTGGTCGAAGCCGGCCAGTTGCTGGCCGAACGCGAACGCGCACTGCGCGACAA
CGAAGAGCGTTTGCGGCTGATCATCGAAGGCGTCAAGGACTACGGCATCTTCGCGCTGGACCGCAACGGCTTCATCACCA
CCTGGAACGCAGGGGCCGAACGTATCAAGGGCTACACGGAGCAGGAGATCATCGGCCAGCACTTTTCTGTGTTCTATCTG
CAACAGGAGTGTCCGCAACACCCCGACATGGCGCTGCATGAGGCCACCGTCAACGGCCGTTATACCGAAGAAGGCTGGCG
CCAACGCAAGGATGGCAGCCGTTTCTGGGCCAGTGTGGTGATCACCGCACAGTACGACAGCAATGACGAACTGCGCGGTT
TTTCCAAGATCACCCGTGACATCAGTGATCGTCGCGTTGCCGAAATTGCCCTGGGCACTGCGCGCGAGGAAGCAGAACGC
GCCAGCCGGGCCAAAAGTGAATTCCTGTCGCGCATGAGCCATGAGCTGCGCACGCCGCTGAACTCGATTCTGGGCTTTGC
CCAGTTGCTGGACATGGACTCCCCCGCCAGCCAGCGCCCGCAAATCGGTCATATTCTGCGGGCGGGCCAGCATCTGCTGA
AGCTGATCAATGAAGTGCTCGACATCGCCAGAATCGAAGCCGGGCATGTTTCCCTGATCCTTGAGCCGGTATCCCTGTCG
AACGTGCTTGAAGAAGCCCTGGTGCTGGTCTCGCCAATGGCCGCCGACGCCAATATCGAATTGAAGCCCTTGCCGAGCCT
GCCTGACGATATCGGTGTGGTCGCTGATCGCCAGCGCTTGATTCAGGTGTTGCTGAACCTGCTGTCCAACGCCATCAAAT
ACAACCGGCCCGCTGGTCAGGTACGGATTGAAATCGAGCAGATCGCCGAGCAGGTCACGATAAGCGTAGTGGACACCGGC
TACGGGATTGCGCCGGAGCGTATCGGACAGCTGTTCAAGCCGTTCGAACGCCTGGATGCCAACCCGAGCGTCGAAGGGAC
CGGGCTGGGACTGGCGCTGAGCAAAAGCATGCTGGAGATGATGCACGGCACGCTCTCCGTACAGAACACGCCGGACGAAG
GCTGCCGGTTCATACTGGCGCTGCCGCTTGTGCGGGTGCAGCCGCCTGCCGCCACTCTGCCGCGTCAAGCTGACACTCGC
CTCGAGATAACGCCTGATGCCCGCTCGCCTGCCCGACCGGCCTATCACGGCAAGCTGCTGTGCATCGAAGACAACCTGTC
GAGCATGGCCTTGATTGAAACGCTGCTGCAACGCAGACCGGGTATCCAGTTGCTGTCGAGCATGCAGGGCCAACTGGGGC
TCGACCTGGCGCGCCAGCATGCGCCACAGCTGATTCTTCTCGACCTCAACCTGCCGGACATCAAGGGGCTTGAAGTGCTG
CAACGTCTGCGCCAACTGCCGGCTACCGCTCAGACGCCCGTGCTGATGATCACTGCCGACACCAGTGATAAAGCCCATCG
CGAACTGAAACAGGCCGGCGCCACGGCCATTGTGATCAAACCCATCCAGGTGCCAGTGTTCCTTGCCCTCCTGGACCAGT
ATTTACCGGAGCCCACATGA

Upstream 100 bases:

>100_bases
TGGAAAAGGTCATCGGCAAGCTCGGCGCCTCGGACCGCACTCAGGCGGCGGTACGCGGTGTGGCACTGGGGCTGGTGAGT
CAATCGACGAGCGACTGGCA

Downstream 100 bases:

>100_bases
CCGGCGACTTTCGCATTCTGATCATCGACGACCAGCGGCCCAACCTTGATCTGATGGAGCAACTGCTTGCCCGCGAGGGG
CTGACCAATGTCTTGAGCAG

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MTAHASSRWEGLPLRGKALVAISLPLAILMFSLVLIYIAERQTARAEEDVRRVLLVQGDIQTLHTQIAEGAASVRGYLLT
HQEDFLPGYLNAQPLIEAALARLNTNVRDEQMREHLKAIEPLINTKVEGLEKLRSMNREDRETVARILIENKYVLDQLRE
RIGIMREREDALLAERTEAAAATRERLLLSTLLAAACGIFGAILAVLMLSKGIVARVHQVQRNAQRLALGHPLLPQPPEK
DEIGQLGTRLVEAGQLLAERERALRDNEERLRLIIEGVKDYGIFALDRNGFITTWNAGAERIKGYTEQEIIGQHFSVFYL
QQECPQHPDMALHEATVNGRYTEEGWRQRKDGSRFWASVVITAQYDSNDELRGFSKITRDISDRRVAEIALGTAREEAER
ASRAKSEFLSRMSHELRTPLNSILGFAQLLDMDSPASQRPQIGHILRAGQHLLKLINEVLDIARIEAGHVSLILEPVSLS
NVLEEALVLVSPMAADANIELKPLPSLPDDIGVVADRQRLIQVLLNLLSNAIKYNRPAGQVRIEIEQIAEQVTISVVDTG
YGIAPERIGQLFKPFERLDANPSVEGTGLGLALSKSMLEMMHGTLSVQNTPDEGCRFILALPLVRVQPPAATLPRQADTR
LEITPDARSPARPAYHGKLLCIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKGLEVL
QRLRQLPATAQTPVLMITADTSDKAHRELKQAGATAIVIKPIQVPVFLALLDQYLPEPT

Sequences:

>Translated_779_residues
MTAHASSRWEGLPLRGKALVAISLPLAILMFSLVLIYIAERQTARAEEDVRRVLLVQGDIQTLHTQIAEGAASVRGYLLT
HQEDFLPGYLNAQPLIEAALARLNTNVRDEQMREHLKAIEPLINTKVEGLEKLRSMNREDRETVARILIENKYVLDQLRE
RIGIMREREDALLAERTEAAAATRERLLLSTLLAAACGIFGAILAVLMLSKGIVARVHQVQRNAQRLALGHPLLPQPPEK
DEIGQLGTRLVEAGQLLAERERALRDNEERLRLIIEGVKDYGIFALDRNGFITTWNAGAERIKGYTEQEIIGQHFSVFYL
QQECPQHPDMALHEATVNGRYTEEGWRQRKDGSRFWASVVITAQYDSNDELRGFSKITRDISDRRVAEIALGTAREEAER
ASRAKSEFLSRMSHELRTPLNSILGFAQLLDMDSPASQRPQIGHILRAGQHLLKLINEVLDIARIEAGHVSLILEPVSLS
NVLEEALVLVSPMAADANIELKPLPSLPDDIGVVADRQRLIQVLLNLLSNAIKYNRPAGQVRIEIEQIAEQVTISVVDTG
YGIAPERIGQLFKPFERLDANPSVEGTGLGLALSKSMLEMMHGTLSVQNTPDEGCRFILALPLVRVQPPAATLPRQADTR
LEITPDARSPARPAYHGKLLCIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKGLEVL
QRLRQLPATAQTPVLMITADTSDKAHRELKQAGATAIVIKPIQVPVFLALLDQYLPEPT
>Mature_778_residues
TAHASSRWEGLPLRGKALVAISLPLAILMFSLVLIYIAERQTARAEEDVRRVLLVQGDIQTLHTQIAEGAASVRGYLLTH
QEDFLPGYLNAQPLIEAALARLNTNVRDEQMREHLKAIEPLINTKVEGLEKLRSMNREDRETVARILIENKYVLDQLRER
IGIMREREDALLAERTEAAAATRERLLLSTLLAAACGIFGAILAVLMLSKGIVARVHQVQRNAQRLALGHPLLPQPPEKD
EIGQLGTRLVEAGQLLAERERALRDNEERLRLIIEGVKDYGIFALDRNGFITTWNAGAERIKGYTEQEIIGQHFSVFYLQ
QECPQHPDMALHEATVNGRYTEEGWRQRKDGSRFWASVVITAQYDSNDELRGFSKITRDISDRRVAEIALGTAREEAERA
SRAKSEFLSRMSHELRTPLNSILGFAQLLDMDSPASQRPQIGHILRAGQHLLKLINEVLDIARIEAGHVSLILEPVSLSN
VLEEALVLVSPMAADANIELKPLPSLPDDIGVVADRQRLIQVLLNLLSNAIKYNRPAGQVRIEIEQIAEQVTISVVDTGY
GIAPERIGQLFKPFERLDANPSVEGTGLGLALSKSMLEMMHGTLSVQNTPDEGCRFILALPLVRVQPPAATLPRQADTRL
EITPDARSPARPAYHGKLLCIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKGLEVLQ
RLRQLPATAQTPVLMITADTSDKAHRELKQAGATAIVIKPIQVPVFLALLDQYLPEPT

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=393, Percent_Identity=35.3689567430025, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI48994928, Length=444, Percent_Identity=28.1531531531532, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788713, Length=403, Percent_Identity=29.0322580645161, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=35.8870967741936, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=30.5343511450382, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=32.9411764705882, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=30.9917355371901, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=32.8703703703704, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.5652173913043, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=29.1845493562232, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=27.3127753303965, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.9559471365639, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=28.125, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=26.6355140186916, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788279, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86575; Mature: 86444

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHASSRWEGLPLRGKALVAISLPLAILMFSLVLIYIAERQTARAEEDVRRVLLVQGDI
CCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QTLHTQIAEGAASVRGYLLTHQEDFLPGYLNAQPLIEAALARLNTNVRDEQMREHLKAIE
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PLINTKVEGLEKLRSMNREDRETVARILIENKYVLDQLRERIGIMREREDALLAERTEAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATRERLLLSTLLAAACGIFGAILAVLMLSKGIVARVHQVQRNAQRLALGHPLLPQPPEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEIGQLGTRLVEAGQLLAERERALRDNEERLRLIIEGVKDYGIFALDRNGFITTWNAGAE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCEEEEECCCHH
RIKGYTEQEIIGQHFSVFYLQQECPQHPDMALHEATVNGRYTEEGWRQRKDGSRFWASVV
HHCCCCHHHHHHHHHHHEEEHHHCCCCCCCHHHHHCCCCCCCHHHHHHCCCCHHEEEEEE
ITAQYDSNDELRGFSKITRDISDRRVAEIALGTAREEAERASRAKSEFLSRMSHELRTPL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
NSILGFAQLLDMDSPASQRPQIGHILRAGQHLLKLINEVLDIARIEAGHVSLILEPVSLS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
NVLEEALVLVSPMAADANIELKPLPSLPDDIGVVADRQRLIQVLLNLLSNAIKYNRPAGQ
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VRIEIEQIAEQVTISVVDTGYGIAPERIGQLFKPFERLDANPSVEGTGLGLALSKSMLEM
EEEEHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MHGTLSVQNTPDEGCRFILALPLVRVQPPAATLPRQADTRLEITPDARSPARPAYHGKLL
HHCCCEECCCCHHHHHHHHHCCHHEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEE
CIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKGLEVL
EEECCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
QRLRQLPATAQTPVLMITADTSDKAHRELKQAGATAIVIKPIQVPVFLALLDQYLPEPT
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAHASSRWEGLPLRGKALVAISLPLAILMFSLVLIYIAERQTARAEEDVRRVLLVQGDI
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QTLHTQIAEGAASVRGYLLTHQEDFLPGYLNAQPLIEAALARLNTNVRDEQMREHLKAIE
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PLINTKVEGLEKLRSMNREDRETVARILIENKYVLDQLRERIGIMREREDALLAERTEAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATRERLLLSTLLAAACGIFGAILAVLMLSKGIVARVHQVQRNAQRLALGHPLLPQPPEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEIGQLGTRLVEAGQLLAERERALRDNEERLRLIIEGVKDYGIFALDRNGFITTWNAGAE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCEEEEECCCHH
RIKGYTEQEIIGQHFSVFYLQQECPQHPDMALHEATVNGRYTEEGWRQRKDGSRFWASVV
HHCCCCHHHHHHHHHHHEEEHHHCCCCCCCHHHHHCCCCCCCHHHHHHCCCCHHEEEEEE
ITAQYDSNDELRGFSKITRDISDRRVAEIALGTAREEAERASRAKSEFLSRMSHELRTPL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
NSILGFAQLLDMDSPASQRPQIGHILRAGQHLLKLINEVLDIARIEAGHVSLILEPVSLS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
NVLEEALVLVSPMAADANIELKPLPSLPDDIGVVADRQRLIQVLLNLLSNAIKYNRPAGQ
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VRIEIEQIAEQVTISVVDTGYGIAPERIGQLFKPFERLDANPSVEGTGLGLALSKSMLEM
EEEEHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MHGTLSVQNTPDEGCRFILALPLVRVQPPAATLPRQADTRLEITPDARSPARPAYHGKLL
HHCCCEECCCCHHHHHHHHHCCHHEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEE
CIEDNLSSMALIETLLQRRPGIQLLSSMQGQLGLDLARQHAPQLILLDLNLPDIKGLEVL
EEECCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
QRLRQLPATAQTPVLMITADTSDKAHRELKQAGATAIVIKPIQVPVFLALLDQYLPEPT
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]