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The map label for this gene is ectB [H]

Identifier: 66045166

GI number: 66045166

Start: 2198097

End: 2199377

Strand: Direct

Name: ectB [H]

Synonym: Psyr_1925

Alternate gene names: 66045166

Gene position: 2198097-2199377 (Clockwise)

Preceding gene: 66045165

Following gene: 66045167

Centisome position: 36.07

GC content: 56.13

Gene sequence:

>1281_bases
ATGAACCCATCAATGGCTATCTACGAGCGTGAGTCGAATGTGCGTTCTTATTGTCGCGACTGTGACGTTGTGTTTGCGAC
GGCGCAAGGGGCAGTGATCGAAGACGTCGAGGGGCGGCAGTTCATCGATTTTTTTGCGGGGGCCGGATCACTGAACTATG
GCCACAATAACCCGCGTTTGAAAAAAGAGCTGTTGGACTATATTCAGCAGGACGGCATCACGACCACCCTGGACTTTCAC
AGCGCTGCGAAGTCTCGGTTTATCGAACAGTTCGAGCGGATTATCCTCACGCCGCGGGGGATGAACTACAAACTGCAGTT
CACCGGGCCCACGGGGACCAATGCAATCGAGGCCGCCTTGAAGCTGGCCCGCAAGATCACCGGACGCACTTGCATCGCTG
CGTTTACCCATGCATTTCACGGCGTCACGCTGGGCTCGCTGGCGCTGACCGCCAACGCCGATAAAAGAGCCGTCTCTGGC
GTAGAGCTGTCAAACGTCGTTCGGCTGCCTTATGACGGATTTCTGGGGCGTGACATTGACAGCGCGCATATCATTGAAAC
GATGTTCTCCTCAGCAGGCGCAGGTTTCGAGCCGCCGGCGGCCATTATTCTGGAAGTTGTGCAGGGCGAGGGCGGTTTGA
ATTGCGCGCGGCCGCAATGGTTACAGAGAATTCAACAGCTGTGCCGGGCCTCAGGTGCGCTACTGATCATTGACGATATT
CAAGCCGGTTGCGGTCGTACGGGCACGTTTTTCAGCTTCGAATCTGCCGATATATCCCCCGACATCATTTGCCTTTCAAA
GTCCATCAGCGGTTATGGTCTGCCGATGTCACTGGTGCTGATAAAACCGGAGCACGATCAGTGGGCGCCCGGTGAACACA
ATGGCACCTTCCGTGGAAACAACACTGCATTCGTGACGGCTGCGGCGGCACTGAGCTATTGGCAAGACAATGCGTTCGAG
CGCTCGATAGCGCAACGGTCCGCCGTCCTGCGCCTTGCACTGGAAAAAATAATTGCTCATTCACCCCCCGAGGCTGTCCG
CATTGTCGGGAGAGGGCTGTTCATGGGATTGAGATTTGGCGACTCACGGCGCGCGAGCAGACTGTCTGCAGAATGCCTGT
CCCAAGGTCTGCTTGTGGAAACCTGTGGCCCCTTGAATGAAGTGCTCAAGCTGATGCCGCCGCTGACCATCGATCTGCCT
GTACTAGAGCGCGGACTGGACATCTTGAAACGTGCCTACCTTTCTACCTTACACAACGAGTCATCGCGAGGGATTGCCTG
A

Upstream 100 bases:

>100_bases
TCAAGGACATGCTGTCGATATTTTACGGGCCCGAGAAAAGCCTGGGGCATTACATCATGGCGCGAGCGTAGTTTAATTTT
TCCGGGCAAGGGAAGCAGGC

Downstream 100 bases:

>100_bases
TGGATTTAATGGTTGGAGATACCCGTACATTGTCTGCCTGTGCGTTGGGCGATGAGTTCATCCTGCAAGAGCTTGCACAA
TTAAGAGACGAACTGATCCA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNPSMAIYERESNVRSYCRDCDVVFATAQGAVIEDVEGRQFIDFFAGAGSLNYGHNNPRLKKELLDYIQQDGITTTLDFH
SAAKSRFIEQFERIILTPRGMNYKLQFTGPTGTNAIEAALKLARKITGRTCIAAFTHAFHGVTLGSLALTANADKRAVSG
VELSNVVRLPYDGFLGRDIDSAHIIETMFSSAGAGFEPPAAIILEVVQGEGGLNCARPQWLQRIQQLCRASGALLIIDDI
QAGCGRTGTFFSFESADISPDIICLSKSISGYGLPMSLVLIKPEHDQWAPGEHNGTFRGNNTAFVTAAAALSYWQDNAFE
RSIAQRSAVLRLALEKIIAHSPPEAVRIVGRGLFMGLRFGDSRRASRLSAECLSQGLLVETCGPLNEVLKLMPPLTIDLP
VLERGLDILKRAYLSTLHNESSRGIA

Sequences:

>Translated_426_residues
MNPSMAIYERESNVRSYCRDCDVVFATAQGAVIEDVEGRQFIDFFAGAGSLNYGHNNPRLKKELLDYIQQDGITTTLDFH
SAAKSRFIEQFERIILTPRGMNYKLQFTGPTGTNAIEAALKLARKITGRTCIAAFTHAFHGVTLGSLALTANADKRAVSG
VELSNVVRLPYDGFLGRDIDSAHIIETMFSSAGAGFEPPAAIILEVVQGEGGLNCARPQWLQRIQQLCRASGALLIIDDI
QAGCGRTGTFFSFESADISPDIICLSKSISGYGLPMSLVLIKPEHDQWAPGEHNGTFRGNNTAFVTAAAALSYWQDNAFE
RSIAQRSAVLRLALEKIIAHSPPEAVRIVGRGLFMGLRFGDSRRASRLSAECLSQGLLVETCGPLNEVLKLMPPLTIDLP
VLERGLDILKRAYLSTLHNESSRGIA
>Mature_426_residues
MNPSMAIYERESNVRSYCRDCDVVFATAQGAVIEDVEGRQFIDFFAGAGSLNYGHNNPRLKKELLDYIQQDGITTTLDFH
SAAKSRFIEQFERIILTPRGMNYKLQFTGPTGTNAIEAALKLARKITGRTCIAAFTHAFHGVTLGSLALTANADKRAVSG
VELSNVVRLPYDGFLGRDIDSAHIIETMFSSAGAGFEPPAAIILEVVQGEGGLNCARPQWLQRIQQLCRASGALLIIDDI
QAGCGRTGTFFSFESADISPDIICLSKSISGYGLPMSLVLIKPEHDQWAPGEHNGTFRGNNTAFVTAAAALSYWQDNAFE
RSIAQRSAVLRLALEKIIAHSPPEAVRIVGRGLFMGLRFGDSRRASRLSAECLSQGLLVETCGPLNEVLKLMPPLTIDLP
VLERGLDILKRAYLSTLHNESSRGIA

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=424, Percent_Identity=26.4150943396226, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI13994255, Length=424, Percent_Identity=24.0566037735849, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI284507298, Length=319, Percent_Identity=26.6457680250784, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=25.1798561151079, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI37574042, Length=411, Percent_Identity=24.8175182481752, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI188536080, Length=420, Percent_Identity=22.3809523809524, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI38679950, Length=420, Percent_Identity=22.3809523809524, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI38679946, Length=420, Percent_Identity=22.3809523809524, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI226442705, Length=313, Percent_Identity=24.9201277955272, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI226442709, Length=313, Percent_Identity=24.9201277955272, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=31.6279069767442, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=32.1867321867322, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=28.7179487179487, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1789759, Length=402, Percent_Identity=26.6169154228856, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786991, Length=401, Percent_Identity=26.6832917705736, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788044, Length=390, Percent_Identity=27.1794871794872, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786349, Length=361, Percent_Identity=27.7008310249307, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25144271, Length=417, Percent_Identity=26.378896882494, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=25.3424657534247, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=212, Percent_Identity=31.1320754716981, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=23.8875878220141, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541228, Length=436, Percent_Identity=20.8715596330275, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=28.8683602771363, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324432, Length=417, Percent_Identity=26.6187050359712, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=26.9953051643192, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21357415, Length=427, Percent_Identity=25.2927400468384, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=26.7772511848341, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21356575, Length=404, Percent_Identity=25, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281366494, Length=407, Percent_Identity=21.8673218673219, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667139, Length=407, Percent_Identity=21.8673218673219, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667143, Length=407, Percent_Identity=21.8673218673219, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46395; Mature: 46395

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSMAIYERESNVRSYCRDCDVVFATAQGAVIEDVEGRQFIDFFAGAGSLNYGHNNPRL
CCCCCEEEECHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCCCCCCCCCHH
KKELLDYIQQDGITTTLDFHSAAKSRFIEQFERIILTPRGMNYKLQFTGPTGTNAIEAAL
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHHHHH
KLARKITGRTCIAAFTHAFHGVTLGSLALTANADKRAVSGVELSNVVRLPYDGFLGRDID
HHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCHHCEEECCCCCCCCCCCC
SAHIIETMFSSAGAGFEPPAAIILEVVQGEGGLNCARPQWLQRIQQLCRASGALLIIDDI
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC
QAGCGRTGTFFSFESADISPDIICLSKSISGYGLPMSLVLIKPEHDQWAPGEHNGTFRGN
CCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
NTAFVTAAAALSYWQDNAFERSIAQRSAVLRLALEKIIAHSPPEAVRIVGRGLFMGLRFG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEC
DSRRASRLSAECLSQGLLVETCGPLNEVLKLMPPLTIDLPVLERGLDILKRAYLSTLHNE
CCHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
SSRGIA
CCCCCC
>Mature Secondary Structure
MNPSMAIYERESNVRSYCRDCDVVFATAQGAVIEDVEGRQFIDFFAGAGSLNYGHNNPRL
CCCCCEEEECHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCCCCCCCCCHH
KKELLDYIQQDGITTTLDFHSAAKSRFIEQFERIILTPRGMNYKLQFTGPTGTNAIEAAL
HHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHHHHH
KLARKITGRTCIAAFTHAFHGVTLGSLALTANADKRAVSGVELSNVVRLPYDGFLGRDID
HHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCHHCEEECCCCCCCCCCCC
SAHIIETMFSSAGAGFEPPAAIILEVVQGEGGLNCARPQWLQRIQQLCRASGALLIIDDI
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC
QAGCGRTGTFFSFESADISPDIICLSKSISGYGLPMSLVLIKPEHDQWAPGEHNGTFRGN
CCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
NTAFVTAAAALSYWQDNAFERSIAQRSAVLRLALEKIIAHSPPEAVRIVGRGLFMGLRFG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEC
DSRRASRLSAECLSQGLLVETCGPLNEVLKLMPPLTIDLPVLERGLDILKRAYLSTLHNE
CCHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
SSRGIA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]