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The map label for this gene is fadB [H]

Identifier: 66045119

GI number: 66045119

Start: 2150370

End: 2151059

Strand: Reverse

Name: fadB [H]

Synonym: Psyr_1875

Alternate gene names: 66045119

Gene position: 2151059-2150370 (Counterclockwise)

Preceding gene: 66045120

Following gene: 66045118

Centisome position: 35.3

GC content: 62.03

Gene sequence:

>690_bases
ATGAGTGATCTGGTCTCGTACCATCTGGACGACGGTGTCGCCACGCTGACCCTGAACAGCGGCAAGGTCAATGCCATTTC
CCCGGACGTGATCGTTGCGTTCAACGCCGCACTGGATCAGGCCGAAAAGGATCGGGCCATCGTTATTCTCACCGGCCAGC
CGGGCATTCTGTCGGGCGGCTACGACCTCAAGGTCATGACCTCCAGCGCCGAGGCCGCGATCGAGCTGGTCGCACAGGGC
TCGACGCTGGCACGGCGCATGCTGTCGCACCCCTTCCCGATCATCGTCGCCTGCCCCGGCCACGCGGTTGCCAAGGGCGC
CTTTCTGCTGCTGTCCGCCGATTATCGAATCGGTGTCGCCGGGCCGTTCAGTATCGGCCTGAACGAAGTGCAGATCGGCA
TGACCATGCACCACGCCGGCATCGAACTGGCGCGCGACCGCCTGCGCAAGTCGGCTTTCAATCGCTCGGTAATCAACGCC
GAGATGTTCGACCCTGAAGCAGCGATGGCCGCCGGTTTCCTCGACCGGGTGGTCAGCATCGAAGAGCTGCAAAGCACCGC
GCTGGCCGTCGCCGGGCAGTTGAAGAAGATCAATATGAGCGCGCACAAGAAGACCAAACTCAAGGTCAGAAAGGCTTTGC
TCGACACGCTGGAGGCCGCGATCGAACAGGATCGACAGCACATGCTGTGA

Upstream 100 bases:

>100_bases
AGCCATTGATCGGCACACTGTTCAGTGACCCGGCAGTCAGCGCTTTACCTGTTCCTTATGGATGAGTAACGTCTGCTCAC
TTCAATAAAGGAATCACGCC

Downstream 100 bases:

>100_bases
TCCCCAACCGAAGCCCGTGCCAACGGGCTTTCGTTTATCGGCGAACTCATACGCATTTGATCAATCTGATCAGCGACCGC
GCATGTTTTTGCGCCACTGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSDLVSYHLDDGVATLTLNSGKVNAISPDVIVAFNAALDQAEKDRAIVILTGQPGILSGGYDLKVMTSSAEAAIELVAQG
STLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVAGPFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINA
EMFDPEAAMAAGFLDRVVSIEELQSTALAVAGQLKKINMSAHKKTKLKVRKALLDTLEAAIEQDRQHML

Sequences:

>Translated_229_residues
MSDLVSYHLDDGVATLTLNSGKVNAISPDVIVAFNAALDQAEKDRAIVILTGQPGILSGGYDLKVMTSSAEAAIELVAQG
STLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVAGPFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINA
EMFDPEAAMAAGFLDRVVSIEELQSTALAVAGQLKKINMSAHKKTKLKVRKALLDTLEAAIEQDRQHML
>Mature_228_residues
SDLVSYHLDDGVATLTLNSGKVNAISPDVIVAFNAALDQAEKDRAIVILTGQPGILSGGYDLKVMTSSAEAAIELVAQGS
TLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVAGPFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINAE
MFDPEAAMAAGFLDRVVSIEELQSTALAVAGQLKKINMSAHKKTKLKVRKALLDTLEAAIEQDRQHML

Specific function: Catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the 3- hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI62530384, Length=223, Percent_Identity=28.2511210762332, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI295842266, Length=222, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24583165, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921018, Length=229, Percent_Identity=25.3275109170306, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR018376
- InterPro:   IPR012799
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =4.2.1.17; =5.1.2.3; =5.3.3.8; =1.1.1.35 [H]

Molecular weight: Translated: 24458; Mature: 24327

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLVSYHLDDGVATLTLNSGKVNAISPDVIVAFNAALDQAEKDRAIVILTGQPGILSGG
CCCCHHEECCCCEEEEEECCCEEEEECCCEEEEEEHHHCCCCCCCEEEEEECCCCEEECC
YDLKVMTSSAEAAIELVAQGSTLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVA
EEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCHHHCCEEEEEECCCEEECC
GPFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINAEMFDPEAAMAAGFLDRVVSI
CCHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHH
EELQSTALAVAGQLKKINMSAHKKTKLKVRKALLDTLEAAIEQDRQHML
HHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLVSYHLDDGVATLTLNSGKVNAISPDVIVAFNAALDQAEKDRAIVILTGQPGILSGG
CCCHHEECCCCEEEEEECCCEEEEECCCEEEEEEHHHCCCCCCCEEEEEECCCCEEECC
YDLKVMTSSAEAAIELVAQGSTLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVA
EEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCHHHCCEEEEEECCCEEECC
GPFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINAEMFDPEAAMAAGFLDRVVSI
CCHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHH
EELQSTALAVAGQLKKINMSAHKKTKLKVRKALLDTLEAAIEQDRQHML
HHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA