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The map label for this gene is minD [H]

Identifier: 66044857

GI number: 66044857

Start: 1814844

End: 1815656

Strand: Reverse

Name: minD [H]

Synonym: Psyr_1612

Alternate gene names: 66044857

Gene position: 1815656-1814844 (Counterclockwise)

Preceding gene: 66044858

Following gene: 66044856

Centisome position: 29.8

GC content: 58.79

Gene sequence:

>813_bases
TTGGCCAAGATTCTCGTTGTTACATCCGGCAAGGGTGGTGTGGGCAAGACCACCACCAGCGCCGCCATCGGTACCGGCCT
CGCACTGCGCGGCCACAAGACAGTCATCGTCGACTTCGACGTCGGTCTGCGTAACCTCGACCTGATCATGGGTTGCGAAC
GTCGTGTCGTGTATGACTTCGTCAACGTGGTCAATGGTGAAGCCAACCTGCAACAGGCGCTGATCAAGGACAAGAAGATC
GAAGGCCTGTTCGTGCTGGCCGCCAGCCAGACCCGCGACAAGGAAGCACTGACCAAGGAGGGCGTTGAAAAAGTCCTCAT
GGAGCTGAAGGAATCCTTCGAATACATCGTCTGCGATTCGCCGGCCGGCATCGAAACCGGTGCTCACCTGGCCATGTACT
TCGCCGACGAAGCCATCGTCGTGACCAACCCTGAAGTCTCGTCGGTGCGTGACTCCGACCGCATGCTGGGCCTGCTGGCC
AGCAAATCGCGTCGCGCCGAACGCGGCGAAGACCCGATCAAGGAACACTTGCTGCTGACCCGCTACAACCCTGAGCGCGT
CAGCAAGGGCGAAATGCTCGGCGTGGAAGACGTCAAGGAAATCCTTGCCGTTACCCTGCTCGGCGTGATTCCCGAATCCC
AGGCTGTACTGAAAGCTTCCAACCAGGGCGTGCCGGTCATTCTCGATGACCAGAGCGACGCGGGTCAGGCCTACAGCGAT
GCGGTCGACCGCCTGCTGGGCAAAACACTTGAGCACCGGTTTCTGGATGTGCATAAGAAAGGATTCTTTGAACGCCTGTT
CGGGGGTAATTAA

Upstream 100 bases:

>100_bases
CGGAATCAGACCCCAGGACTTCCAGAATGCTTCGGCGTGCGCGGCGCCAGGAGATGCCTTTCAGGGACTCAATGTCCTTT
TCCTCTAGGGGTGATACACC

Downstream 100 bases:

>100_bases
TGAATATTTTTGACTTCTTTCGTGACCGCAAAAAAGGAAGCACGGCCTCGGTAGCGAAAGAGCGTCTACAGATCATCGTT
GCTCACGAACGCGGCCAACG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAKILVVTSGKGGVGKTTTSAAIGTGLALRGHKTVIVDFDVGLRNLDLIMGCERRVVYDFVNVVNGEANLQQALIKDKKI
EGLFVLAASQTRDKEALTKEGVEKVLMELKESFEYIVCDSPAGIETGAHLAMYFADEAIVVTNPEVSSVRDSDRMLGLLA
SKSRRAERGEDPIKEHLLLTRYNPERVSKGEMLGVEDVKEILAVTLLGVIPESQAVLKASNQGVPVILDDQSDAGQAYSD
AVDRLLGKTLEHRFLDVHKKGFFERLFGGN

Sequences:

>Translated_270_residues
MAKILVVTSGKGGVGKTTTSAAIGTGLALRGHKTVIVDFDVGLRNLDLIMGCERRVVYDFVNVVNGEANLQQALIKDKKI
EGLFVLAASQTRDKEALTKEGVEKVLMELKESFEYIVCDSPAGIETGAHLAMYFADEAIVVTNPEVSSVRDSDRMLGLLA
SKSRRAERGEDPIKEHLLLTRYNPERVSKGEMLGVEDVKEILAVTLLGVIPESQAVLKASNQGVPVILDDQSDAGQAYSD
AVDRLLGKTLEHRFLDVHKKGFFERLFGGN
>Mature_269_residues
AKILVVTSGKGGVGKTTTSAAIGTGLALRGHKTVIVDFDVGLRNLDLIMGCERRVVYDFVNVVNGEANLQQALIKDKKIE
GLFVLAASQTRDKEALTKEGVEKVLMELKESFEYIVCDSPAGIETGAHLAMYFADEAIVVTNPEVSSVRDSDRMLGLLAS
KSRRAERGEDPIKEHLLLTRYNPERVSKGEMLGVEDVKEILAVTLLGVIPESQAVLKASNQGVPVILDDQSDAGQAYSDA
VDRLLGKTLEHRFLDVHKKGFFERLFGGN

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=73.7037037037037, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29385; Mature: 29254

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILVVTSGKGGVGKTTTSAAIGTGLALRGHKTVIVDFDVGLRNLDLIMGCERRVVYDF
CEEEEEEECCCCCCCCCCCHHHHCCCEEECCCEEEEEEECCCCCHHHHHHCCCHHHHHHH
VNVVNGEANLQQALIKDKKIEGLFVLAASQTRDKEALTKEGVEKVLMELKESFEYIVCDS
HHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECC
PAGIETGAHLAMYFADEAIVVTNPEVSSVRDSDRMLGLLASKSRRAERGEDPIKEHLLLT
CCCCCCCCEEEEEEECCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCEEEE
RYNPERVSKGEMLGVEDVKEILAVTLLGVIPESQAVLKASNQGVPVILDDQSDAGQAYSD
ECCHHHCCCCCEECHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHHHH
AVDRLLGKTLEHRFLDVHKKGFFERLFGGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKILVVTSGKGGVGKTTTSAAIGTGLALRGHKTVIVDFDVGLRNLDLIMGCERRVVYDF
EEEEEEECCCCCCCCCCCHHHHCCCEEECCCEEEEEEECCCCCHHHHHHCCCHHHHHHH
VNVVNGEANLQQALIKDKKIEGLFVLAASQTRDKEALTKEGVEKVLMELKESFEYIVCDS
HHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECC
PAGIETGAHLAMYFADEAIVVTNPEVSSVRDSDRMLGLLASKSRRAERGEDPIKEHLLLT
CCCCCCCCEEEEEEECCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCEEEE
RYNPERVSKGEMLGVEDVKEILAVTLLGVIPESQAVLKASNQGVPVILDDQSDAGQAYSD
ECCHHHCCCCCEECHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHHHH
AVDRLLGKTLEHRFLDVHKKGFFERLFGGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]