Click here to switch to the map view.

The map label for this gene is mas [H]

Identifier: 66044845

GI number: 66044845

Start: 1799854

End: 1800816

Strand: Direct

Name: mas [H]

Synonym: Psyr_1600

Alternate gene names: 66044845

Gene position: 1799854-1800816 (Clockwise)

Preceding gene: 66044842

Following gene: 66044852

Centisome position: 29.54

GC content: 63.14

Gene sequence:

>963_bases
GTGAAAGCATTGCAAGGCGTTGAAGGACATGTGGAATGGGTCGAGGAGCCGAGTCCGGCCCTCGATGTGGGGCAGGTACG
TATCAAAGTGGCTGCGGCAGGTTTGAATCGTGCCGATCTGTTACAGCGCGAGGGCAAGTATCCGCCGCCGCCCGGAGTCA
CTCAGACGCTGGGTCTGGAGTGCTCCGGCGTGATCGCCGAAGTCGGTCCGGGTTCGCCCTGGGTGGTTGGAGACCGCGTC
TGCGCGCTGTTGGCGGGCGGGGCGATGGCCGAAGAAGTGGTGGTCGATGGGCGACACGTGCTGCCCGTGCCGGAAGGGCT
GTCGCTGCATGAGGCGGCAGCCATTCCCGAGGTCTATGCCACGGCGTGGCTGAACCTGTTCGAGCTCGCCGGGCTCAAGC
CAGGCGAGAAGGTGTTGTTGCACGCTGGCGCAAGTGGGGTTGGTTCAGCCGGGATTCAGCTTTGCAAGGCGTTTGGCAAC
CCGGTCTGGGTCAGCGTCGGCTCGGCAGAACGGCTGGCCTATTGCGTCGAACTGGGTGCTCAGGGCGGCGTGGTGCGCAG
CGAAAGTCTTGAAGGCCTGAACGATTTTGCACCGTTCAACGTCATCCTCGACCCGGTGGGGGCGAGCTATGCCGAGCTCA
ATGTAAAACTGCTGGCCCTTGACGGCCGCTGGGTGCTGATCGGCGTCATGAGCGGCCGCGAGGCGAAAGTGGATCTGGCT
CATGTGCTGGGCAAGCGTATCCGGTTGATGGGCTCGACCTTGCGCAGCCGCGACGACACGTTCAAGGCCGACCTGCTCAG
TGACCTGGGACAGCACGTCTGGCCGCTGTTCACTGAAGGCCGCCTCAAGCCGCAACTGGCGAAATCCTTTGCGATCAAGG
ATGCCGAAGCGGCGTTCGAAGAGCTGGCGACCAATACGGTGTCCGGCAAGATCGTGCTGGTGATCGACGAAAGCCTGGTC
TGA

Upstream 100 bases:

>100_bases
GCCGTCTTTGAGGTCGCCGGTTCCTTTGGACCCGGCCGCATAATGCAAAAGCCCGGGCAAAACAGCCACGGGCTCAGTCT
GGACTCACTATGGAGGCACC

Downstream 100 bases:

>100_bases
CCCGGCGGCGCCTCTGGACTCAGCTCCAGTCGTGCACCGGCCAGCCTGCTTTCCGCGCGTGTTCCAGTAACACGGCATCG
GGGTTGACCACGTTAGGGTG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKALQGVEGHVEWVEEPSPALDVGQVRIKVAAAGLNRADLLQREGKYPPPPGVTQTLGLECSGVIAEVGPGSPWVVGDRV
CALLAGGAMAEEVVVDGRHVLPVPEGLSLHEAAAIPEVYATAWLNLFELAGLKPGEKVLLHAGASGVGSAGIQLCKAFGN
PVWVSVGSAERLAYCVELGAQGGVVRSESLEGLNDFAPFNVILDPVGASYAELNVKLLALDGRWVLIGVMSGREAKVDLA
HVLGKRIRLMGSTLRSRDDTFKADLLSDLGQHVWPLFTEGRLKPQLAKSFAIKDAEAAFEELATNTVSGKIVLVIDESLV

Sequences:

>Translated_320_residues
MKALQGVEGHVEWVEEPSPALDVGQVRIKVAAAGLNRADLLQREGKYPPPPGVTQTLGLECSGVIAEVGPGSPWVVGDRV
CALLAGGAMAEEVVVDGRHVLPVPEGLSLHEAAAIPEVYATAWLNLFELAGLKPGEKVLLHAGASGVGSAGIQLCKAFGN
PVWVSVGSAERLAYCVELGAQGGVVRSESLEGLNDFAPFNVILDPVGASYAELNVKLLALDGRWVLIGVMSGREAKVDLA
HVLGKRIRLMGSTLRSRDDTFKADLLSDLGQHVWPLFTEGRLKPQLAKSFAIKDAEAAFEELATNTVSGKIVLVIDESLV
>Mature_320_residues
MKALQGVEGHVEWVEEPSPALDVGQVRIKVAAAGLNRADLLQREGKYPPPPGVTQTLGLECSGVIAEVGPGSPWVVGDRV
CALLAGGAMAEEVVVDGRHVLPVPEGLSLHEAAAIPEVYATAWLNLFELAGLKPGEKVLLHAGASGVGSAGIQLCKAFGN
PVWVSVGSAERLAYCVELGAQGGVVRSESLEGLNDFAPFNVILDPVGASYAELNVKLLALDGRWVLIGVMSGREAKVDLA
HVLGKRIRLMGSTLRSRDDTFKADLLSDLGQHVWPLFTEGRLKPQLAKSFAIKDAEAAFEELATNTVSGKIVLVIDESLV

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=319, Percent_Identity=43.5736677115987, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI22538444, Length=319, Percent_Identity=43.5736677115987, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=28.2958199356913, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI24308257, Length=138, Percent_Identity=39.8550724637681, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI41872631, Length=311, Percent_Identity=29.5819935691318, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194239674, Length=304, Percent_Identity=26.6447368421053, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI13236495, Length=304, Percent_Identity=26.6447368421053, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI28557745, Length=242, Percent_Identity=30.1652892561983, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194239676, Length=160, Percent_Identity=35.625, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47519420, Length=210, Percent_Identity=31.9047619047619, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=301, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=313, Percent_Identity=29.3929712460064, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71987554, Length=364, Percent_Identity=26.3736263736264, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=327, Percent_Identity=28.1345565749235, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=320, Percent_Identity=25.625, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24581345, Length=332, Percent_Identity=26.2048192771084, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221330659, Length=281, Percent_Identity=26.3345195729537, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920632, Length=344, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 33732; Mature: 33732

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALQGVEGHVEWVEEPSPALDVGQVRIKVAAAGLNRADLLQREGKYPPPPGVTQTLGLE
CCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCC
CSGVIAEVGPGSPWVVGDRVCALLAGGAMAEEVVVDGRHVLPVPEGLSLHEAAAIPEVYA
CCCEEEECCCCCCEEEHHHHHHHHHCCCHHHHHEECCCEEECCCCCCCHHHHHHCHHHHH
TAWLNLFELAGLKPGEKVLLHAGASGVGSAGIQLCKAFGNPVWVSVGSAERLAYCVELGA
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCC
QGGVVRSESLEGLNDFAPFNVILDPVGASYAELNVKLLALDGRWVLIGVMSGREAKVDLA
CCCEEECHHHCCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCHHHHH
HVLGKRIRLMGSTLRSRDDTFKADLLSDLGQHVWPLFTEGRLKPQLAKSFAIKDAEAAFE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHCCHHHHHHH
ELATNTVSGKIVLVIDESLV
HHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MKALQGVEGHVEWVEEPSPALDVGQVRIKVAAAGLNRADLLQREGKYPPPPGVTQTLGLE
CCCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCC
CSGVIAEVGPGSPWVVGDRVCALLAGGAMAEEVVVDGRHVLPVPEGLSLHEAAAIPEVYA
CCCEEEECCCCCCEEEHHHHHHHHHCCCHHHHHEECCCEEECCCCCCCHHHHHHCHHHHH
TAWLNLFELAGLKPGEKVLLHAGASGVGSAGIQLCKAFGNPVWVSVGSAERLAYCVELGA
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCC
QGGVVRSESLEGLNDFAPFNVILDPVGASYAELNVKLLALDGRWVLIGVMSGREAKVDLA
CCCEEECHHHCCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCHHHHH
HVLGKRIRLMGSTLRSRDDTFKADLLSDLGQHVWPLFTEGRLKPQLAKSFAIKDAEAAFE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHCCHHHHHHH
ELATNTVSGKIVLVIDESLV
HHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]