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The map label for this gene is 66044836

Identifier: 66044836

GI number: 66044836

Start: 1790517

End: 1790909

Strand: Direct

Name: 66044836

Synonym: Psyr_1591

Alternate gene names: NA

Gene position: 1790517-1790909 (Clockwise)

Preceding gene: 66044835

Following gene: 66044838

Centisome position: 29.38

GC content: 58.02

Gene sequence:

>393_bases
GTGATTGATCATCTGGACCACCTGGTACTGACCACTGCCGATATCGACGCCTGCAAGGATTTTTACGTACGCGTTCTGGG
CATGACCCCTGAACGCTTTCGTCAGGGGCGTCTGGCATTTCGCTTCGGCAATCAGAAAATCAACGTCCATGAACGCGGCA
AGGAGTTCGAGCCCAAGGCTCACTTGCCGGTGCCAGGTGCGCTGGATCTGTGTTTCATCGCCACCATCCCGCTGGAGCAG
GTGATTGTGCACCTGCAGGAGCAGGACTGGCCGATCGTCGAAGGTCCGGTCGAGCGCACCGGTGCTACCGGGCCGATCTG
GTCGGTGTATGTGCGTGATCCGGATCTTAACCTGATCGAAATTTCCGAGCCGGCGGCTGATGCGTCGATGTAA

Upstream 100 bases:

>100_bases
GACGCTGCCACCCGTGCCGAGTGGCGTCGGCTTGGCATTATCTGATCCGAAACCTGACCATTGTCGTAAACAGAACTCTA
TTCCAAACGGAGCTGATCCC

Downstream 100 bases:

>100_bases
TCGCGCTCGATGAGGGCGGTTGCATCATTGCATCAGCAGCCCTTCGCAGGCGCTCCGTCCTTCGGCACGAATGCGCCTTT
TTCGCCTGGCTTGGTGATGA

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MIDHLDHLVLTTADIDACKDFYVRVLGMTPERFRQGRLAFRFGNQKINVHERGKEFEPKAHLPVPGALDLCFIATIPLEQ
VIVHLQEQDWPIVEGPVERTGATGPIWSVYVRDPDLNLIEISEPAADASM

Sequences:

>Translated_130_residues
MIDHLDHLVLTTADIDACKDFYVRVLGMTPERFRQGRLAFRFGNQKINVHERGKEFEPKAHLPVPGALDLCFIATIPLEQ
VIVHLQEQDWPIVEGPVERTGATGPIWSVYVRDPDLNLIEISEPAADASM
>Mature_130_residues
MIDHLDHLVLTTADIDACKDFYVRVLGMTPERFRQGRLAFRFGNQKINVHERGKEFEPKAHLPVPGALDLCFIATIPLEQ
VIVHLQEQDWPIVEGPVERTGATGPIWSVYVRDPDLNLIEISEPAADASM

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=122, Percent_Identity=56.5573770491803, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14659; Mature: 14659

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDHLDHLVLTTADIDACKDFYVRVLGMTPERFRQGRLAFRFGNQKINVHERGKEFEPKA
CCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHCCCEEEEECCEEEECCCCCCCCCCCC
HLPVPGALDLCFIATIPLEQVIVHLQEQDWPIVEGPVERTGATGPIWSVYVRDPDLNLIE
CCCCCCCHHEEEEECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCEEE
ISEPAADASM
ECCCCCCCCC
>Mature Secondary Structure
MIDHLDHLVLTTADIDACKDFYVRVLGMTPERFRQGRLAFRFGNQKINVHERGKEFEPKA
CCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHCCCEEEEECCEEEECCCCCCCCCCCC
HLPVPGALDLCFIATIPLEQVIVHLQEQDWPIVEGPVERTGATGPIWSVYVRDPDLNLIE
CCCCCCCHHEEEEECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCEEE
ISEPAADASM
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]