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The map label for this gene is dapA [H]

Identifier: 66044794

GI number: 66044794

Start: 1741344

End: 1742222

Strand: Direct

Name: dapA [H]

Synonym: Psyr_1548

Alternate gene names: 66044794

Gene position: 1741344-1742222 (Clockwise)

Preceding gene: 66044791

Following gene: 66044795

Centisome position: 28.58

GC content: 59.27

Gene sequence:

>879_bases
ATGATTGCGGGCAGTATGGTGGCACTGGTCACACCAATGGATGCACAAGGTCGTCTGGACTGGGACAGCCTGAGCAAACT
GGTTGACTTCCACTTGCAAGAGGGCACCCACGCCATTGTTGCCGTAGGCACCACCGGTGAATCGGCGACGCTGGATGTGA
ACGAACACATCGAAGTCATCCGCCGGGTGGTCACTCAGGTTGCAGGTCGCATTCCGGTCATCGCCGGTACAGGCGCCAAT
TCGACGCGTGAAGCCGTCGAACTGACCACCAACGCCAAAAATGCGGGTGCCGACGCGTGCCTGCTGGTGACGCCTTACTA
CAACAAGCCGACTCAGGAAGGCCTGTTCCAGCATTTCAGCCACATCGCCAATGCCGTCGACATCCCGCAGATACTCTACA
ACGTGCCGGGCCGTACGGCCTGCGACATGCTGCCAGAGACCGTTGCGCGTTTGTCGACGGTAAAAAACATCGTTGGTATC
AAGGAAGCCACCGGCAACCTGCAACGCGCCAAGGACATCCTGGCCAGCGTCAGCAGCGATTTTCTGGTGTACTCCGGCGA
CGACGCTACAGCAGTCGAATTGATGCTGCTGGGCGGCAAGGGCAATATTTCCGTGACCGCCAACGTTGCACCGCGCGCCA
TGAGCGATCTGTGCGCAGCGGCCATGCGTGGCGATGCGCAAACGGCCCGGGCGATTCACGAAAAGCTCATGCCGCTCAAC
AACACCCTGTTCATCGAATCCAACCCTATCCCCGTGAAGTGGGCCTTGCATGAAATGGGTCTGATGCCAGACGGTATCCG
TCTGCCGCTTACCTGGCTCAGCGAAGCCTGTCATGAACCGCTGCGTCAGGCCATGCGCCAGTCCGGCGTCCTGGTTTAA

Upstream 100 bases:

>100_bases
ACCATCGCTCAGGGGAATGCTCAGAGCGCGGTACTTCGCTTGTACAAGGCTGATAGCGCCAGTACCATTACGGCTCTCTT
TTTCCGGCAGGAGCGGTTGC

Downstream 100 bases:

>100_bases
TTGAGGAAGTATCACGCAATGAAGCGATTGGCCGGACTTTCCGCACTTGCTCTTATTATCTCCAGCACCAGCGGTTGCGG
TTGGCTCTGGGGCGAAGATG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTHAIVAVGTTGESATLDVNEHIEVIRRVVTQVAGRIPVIAGTGAN
STREAVELTTNAKNAGADACLLVTPYYNKPTQEGLFQHFSHIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIVGI
KEATGNLQRAKDILASVSSDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAQTARAIHEKLMPLN
NTLFIESNPIPVKWALHEMGLMPDGIRLPLTWLSEACHEPLRQAMRQSGVLV

Sequences:

>Translated_292_residues
MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTHAIVAVGTTGESATLDVNEHIEVIRRVVTQVAGRIPVIAGTGAN
STREAVELTTNAKNAGADACLLVTPYYNKPTQEGLFQHFSHIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIVGI
KEATGNLQRAKDILASVSSDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAQTARAIHEKLMPLN
NTLFIESNPIPVKWALHEMGLMPDGIRLPLTWLSEACHEPLRQAMRQSGVLV
>Mature_292_residues
MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTHAIVAVGTTGESATLDVNEHIEVIRRVVTQVAGRIPVIAGTGAN
STREAVELTTNAKNAGADACLLVTPYYNKPTQEGLFQHFSHIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIVGI
KEATGNLQRAKDILASVSSDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAQTARAIHEKLMPLN
NTLFIESNPIPVKWALHEMGLMPDGIRLPLTWLSEACHEPLRQAMRQSGVLV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=297, Percent_Identity=29.2929292929293, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI13540533, Length=235, Percent_Identity=25.9574468085106, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=56.8493150684932, Blast_Score=342, Evalue=1e-95,
Organism=Escherichia coli, GI87082415, Length=281, Percent_Identity=33.4519572953737, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786463, Length=241, Percent_Identity=31.5352697095436, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789620, Length=281, Percent_Identity=29.1814946619217, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31258; Mature: 31258

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTHAIVAVGTTGESATLDVNEHIEVI
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHH
RRVVTQVAGRIPVIAGTGANSTREAVELTTNAKNAGADACLLVTPYYNKPTQEGLFQHFS
HHHHHHHHCCCCEEEECCCCCCHHHEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
HIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIVGIKEATGNLQRAKDILASVSSD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
FLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAQTARAIHEKLMPLN
EEEEECCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NTLFIESNPIPVKWALHEMGLMPDGIRLPLTWLSEACHEPLRQAMRQSGVLV
CEEEEECCCCCEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTHAIVAVGTTGESATLDVNEHIEVI
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHH
RRVVTQVAGRIPVIAGTGANSTREAVELTTNAKNAGADACLLVTPYYNKPTQEGLFQHFS
HHHHHHHHCCCCEEEECCCCCCHHHEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
HIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIVGIKEATGNLQRAKDILASVSSD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
FLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAQTARAIHEKLMPLN
EEEEECCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NTLFIESNPIPVKWALHEMGLMPDGIRLPLTWLSEACHEPLRQAMRQSGVLV
CEEEEECCCCCEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA