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The map label for this gene is czcD [H]

Identifier: 66044753

GI number: 66044753

Start: 1692284

End: 1693237

Strand: Direct

Name: czcD [H]

Synonym: Psyr_1506

Alternate gene names: 66044753

Gene position: 1692284-1693237 (Clockwise)

Preceding gene: 66044752

Following gene: 66044754

Centisome position: 27.77

GC content: 54.82

Gene sequence:

>954_bases
ATGAACGCAGGCTCGAACTTCATGAACAGCAACACCAGCTTTACGCACGAGCACGTATATCTCGGCTCGGCACATGATGA
GAATGCAAAACGTACCCTTTGGGTGGTAATACTTACCGTTGTGATGATGGTAGGGGAGATTACTGCTGGGTACCTCACAG
GGTCTATGGCTCTGTTAGCCGATGGATTTCATATGGCTACCCATGCGGGTGCGCTGGGGATCGCAGCGGCGGCTTATGCG
TACGCCAAGCGTCATGCATCCAGTACTCGCTTCAGTTTTGGCACCGGCAAAGTGGGAGATCTGGGCGGCTTTGCATCAGC
GCTTATCCTGGGATTAGTATCTTTGGGAATTGGCGTTGAGTCCATCATTCGGCTGTTCCAGCCTACTAACGTCCAGTTCG
GAACGGCAACGCTGATTGCCATCGTAGGCCTGGGAGTCAACATCGTAAGCGCTCTGCTGCTCGGCCACGGCCACAGGCAT
GACCACGGCCACGGTCATCACGACCATGACCATAGTCCTCATGGAGGGGATAACAACCTTAGGTCAGCGTACATTCATGT
GATTGCCGATGCCCTGACGTCTGTTCTTGCCATCGCTGCCCTGCTTGCTGGCCGCTACCTCGGATGGGTCTGGCTTGATC
CAGCCATGGGTATCGTGGGTGCAATTGTGATCGCACGGTGGGCCTGGAGCCTGATGGGCGCTACTGCGGGAGTTCTGCTG
GATCAAACCGACGATCATGTTGCAGATGAAATTCGCGAGCTGGTTGAGCAAGCTGGCGATGCCAAAATTACCGACCTGCA
CGTGTGGCGTGTTGGTCCGGAAGCCCATGCTGCAATTGTCAGTGTTCTTGGGGCCTCTACAACAAATGCGGATAGCATCC
GTGATCGGTTGAAGCCTGTTCACGAAGTTAGCCACCTCACGATTGAGTTTCGAGCAGCATTGCCTGCTACGTAG

Upstream 100 bases:

>100_bases
ATCACGCCCGGGAGCATGTGGCTAATCCGGCGCTGAGCGATGAAGAGCGGTCCAAGGGCGTCGAAGAGCTTCTCGAAGCC
ATTCGACGTTATTCCAAGTG

Downstream 100 bases:

>100_bases
AGCTTGATGATAATCGGCAAGGCCCCCTGCAACGGGCGCGGGCGCACGCCTTGCCTACTCACTCTATTATTCTGGAATCA
CCTGACTTCAAGCAAACGTG

Product: cation efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNAGSNFMNSNTSFTHEHVYLGSAHDENAKRTLWVVILTVVMMVGEITAGYLTGSMALLADGFHMATHAGALGIAAAAYA
YAKRHASSTRFSFGTGKVGDLGGFASALILGLVSLGIGVESIIRLFQPTNVQFGTATLIAIVGLGVNIVSALLLGHGHRH
DHGHGHHDHDHSPHGGDNNLRSAYIHVIADALTSVLAIAALLAGRYLGWVWLDPAMGIVGAIVIARWAWSLMGATAGVLL
DQTDDHVADEIRELVEQAGDAKITDLHVWRVGPEAHAAIVSVLGASTTNADSIRDRLKPVHEVSHLTIEFRAALPAT

Sequences:

>Translated_317_residues
MNAGSNFMNSNTSFTHEHVYLGSAHDENAKRTLWVVILTVVMMVGEITAGYLTGSMALLADGFHMATHAGALGIAAAAYA
YAKRHASSTRFSFGTGKVGDLGGFASALILGLVSLGIGVESIIRLFQPTNVQFGTATLIAIVGLGVNIVSALLLGHGHRH
DHGHGHHDHDHSPHGGDNNLRSAYIHVIADALTSVLAIAALLAGRYLGWVWLDPAMGIVGAIVIARWAWSLMGATAGVLL
DQTDDHVADEIRELVEQAGDAKITDLHVWRVGPEAHAAIVSVLGASTTNADSIRDRLKPVHEVSHLTIEFRAALPAT
>Mature_317_residues
MNAGSNFMNSNTSFTHEHVYLGSAHDENAKRTLWVVILTVVMMVGEITAGYLTGSMALLADGFHMATHAGALGIAAAAYA
YAKRHASSTRFSFGTGKVGDLGGFASALILGLVSLGIGVESIIRLFQPTNVQFGTATLIAIVGLGVNIVSALLLGHGHRH
DHGHGHHDHDHSPHGGDNNLRSAYIHVIADALTSVLAIAALLAGRYLGWVWLDPAMGIVGAIVIARWAWSLMGATAGVLL
DQTDDHVADEIRELVEQAGDAKITDLHVWRVGPEAHAAIVSVLGASTTNADSIRDRLKPVHEVSHLTIEFRAALPAT

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI20070323, Length=273, Percent_Identity=25.6410256410256, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI222080086, Length=318, Percent_Identity=20.7547169811321, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI40255009, Length=318, Percent_Identity=20.7547169811321, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI52352805, Length=271, Percent_Identity=25.0922509225092, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21359890, Length=261, Percent_Identity=24.5210727969349, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI52351208, Length=125, Percent_Identity=31.2, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786966, Length=294, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564488, Length=286, Percent_Identity=29.020979020979, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193210990, Length=309, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555794, Length=266, Percent_Identity=29.3233082706767, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555796, Length=257, Percent_Identity=29.1828793774319, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320411, Length=245, Percent_Identity=27.3469387755102, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323899, Length=153, Percent_Identity=32.0261437908497, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24645863, Length=315, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33464; Mature: 33464

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGSNFMNSNTSFTHEHVYLGSAHDENAKRTLWVVILTVVMMVGEITAGYLTGSMALLA
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGFHMATHAGALGIAAAAYAYAKRHASSTRFSFGTGKVGDLGGFASALILGLVSLGIGVE
CCHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCHH
SIIRLFQPTNVQFGTATLIAIVGLGVNIVSALLLGHGHRHDHGHGHHDHDHSPHGGDNNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
RSAYIHVIADALTSVLAIAALLAGRYLGWVWLDPAMGIVGAIVIARWAWSLMGATAGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEE
DQTDDHVADEIRELVEQAGDAKITDLHVWRVGPEAHAAIVSVLGASTTNADSIRDRLKPV
CCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHH
HEVSHLTIEFRAALPAT
HHHHHHEEEEEECCCCC
>Mature Secondary Structure
MNAGSNFMNSNTSFTHEHVYLGSAHDENAKRTLWVVILTVVMMVGEITAGYLTGSMALLA
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGFHMATHAGALGIAAAAYAYAKRHASSTRFSFGTGKVGDLGGFASALILGLVSLGIGVE
CCHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCHH
SIIRLFQPTNVQFGTATLIAIVGLGVNIVSALLLGHGHRHDHGHGHHDHDHSPHGGDNNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
RSAYIHVIADALTSVLAIAALLAGRYLGWVWLDPAMGIVGAIVIARWAWSLMGATAGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEE
DQTDDHVADEIRELVEQAGDAKITDLHVWRVGPEAHAAIVSVLGASTTNADSIRDRLKPV
CCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHH
HEVSHLTIEFRAALPAT
HHHHHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA