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The map label for this gene is arsC [H]

Identifier: 66044749

GI number: 66044749

Start: 1689666

End: 1690136

Strand: Reverse

Name: arsC [H]

Synonym: Psyr_1502

Alternate gene names: 66044749

Gene position: 1690136-1689666 (Counterclockwise)

Preceding gene: 66044750

Following gene: 66044748

Centisome position: 27.74

GC content: 58.39

Gene sequence:

>471_bases
ATGAAAGTTCTATTTATGTGTACCGCCAATAGCTGCCGGAGCGTGCTCTCTGAAGGCTTGTTCAACCACCTTGCGCCTGA
CGGAATGGTGGGCGTCAGCTCTGGCAGCTTTCCCAGCGGAAGTTTGAACCCCCGCGCAGTGAGTACCTTGCAAGGTCTAG
GCGTGGATACTTCGGCGCTCTACAGCAAGGGATCGGAGAGTTTCCAGGAAAACCTGCCTGATATTGTCATCACTGTCTGC
GACAAGGCCGGAGGCGAGCCATGCCCGGTATACTTCGGACCCGCCATCAAAAGCCACTGGGGCCTGTCCGACCCCTCGGA
CGTCGAGGGCAGCGATGAGGAGGTCCAGGCCGCGTTTGACGCCACCGTGGCGCATATTCGCCGGCGTTTCGACGCCTTCT
TCGCACTTGACTTCAACGCGCTCGACTCCACGGAGCTGAAACGTGTCCTCGATGAGATAGGTGCACTGTGA

Upstream 100 bases:

>100_bases
GTTATTACTTCAAGGTCGGCAGCCTCCTGACCCTTCCCATCCTGCTCGTCACCTTGGCCGCATTGGCCCTGCGGCTGAGT
CTTCACGCTTAGGATCAATA

Downstream 100 bases:

>100_bases
TGAACGATTCGGTGAAGACCGATCCGAGCGATTTTCCGAGCCTGGATGTATCGCTATTGAACATTCCTACCCAGGATCAA
CTCGCCAAGGGCGAGCCACC

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKVLFMCTANSCRSVLSEGLFNHLAPDGMVGVSSGSFPSGSLNPRAVSTLQGLGVDTSALYSKGSESFQENLPDIVITVC
DKAGGEPCPVYFGPAIKSHWGLSDPSDVEGSDEEVQAAFDATVAHIRRRFDAFFALDFNALDSTELKRVLDEIGAL

Sequences:

>Translated_156_residues
MKVLFMCTANSCRSVLSEGLFNHLAPDGMVGVSSGSFPSGSLNPRAVSTLQGLGVDTSALYSKGSESFQENLPDIVITVC
DKAGGEPCPVYFGPAIKSHWGLSDPSDVEGSDEEVQAAFDATVAHIRRRFDAFFALDFNALDSTELKRVLDEIGAL
>Mature_156_residues
MKVLFMCTANSCRSVLSEGLFNHLAPDGMVGVSSGSFPSGSLNPRAVSTLQGLGVDTSALYSKGSESFQENLPDIVITVC
DKAGGEPCPVYFGPAIKSHWGLSDPSDVEGSDEEVQAAFDATVAHIRRRFDAFFALDFNALDSTELKRVLDEIGAL

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16593; Mature: 16593

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLFMCTANSCRSVLSEGLFNHLAPDGMVGVSSGSFPSGSLNPRAVSTLQGLGVDTSAL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHH
YSKGSESFQENLPDIVITVCDKAGGEPCPVYFGPAIKSHWGLSDPSDVEGSDEEVQAAFD
HHCCCHHHHHCCCCEEEEECCCCCCCCCCEEECCHHHHCCCCCCCCCCCCCHHHHHHHHH
ATVAHIRRRFDAFFALDFNALDSTELKRVLDEIGAL
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLFMCTANSCRSVLSEGLFNHLAPDGMVGVSSGSFPSGSLNPRAVSTLQGLGVDTSAL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHH
YSKGSESFQENLPDIVITVCDKAGGEPCPVYFGPAIKSHWGLSDPSDVEGSDEEVQAAFD
HHCCCHHHHHCCCCEEEEECCCCCCCCCCEEECCHHHHCCCCCCCCCCCCCHHHHHHHHH
ATVAHIRRRFDAFFALDFNALDSTELKRVLDEIGAL
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA