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The map label for this gene is ppa2

Identifier: 66044728

GI number: 66044728

Start: 1670126

End: 1670671

Strand: Reverse

Name: ppa2

Synonym: Psyr_1481

Alternate gene names: 66044728

Gene position: 1670671-1670126 (Counterclockwise)

Preceding gene: 66044729

Following gene: 66044727

Centisome position: 27.42

GC content: 52.56

Gene sequence:

>546_bases
ATGAGCTACACGGATATTCCAGCTGGTAACGCGATCCCCGATGACTTCTTCACCGTTATCGAGATTCCTGCAAACCACTC
GCCGATCAAGTACGAGGTGGACAAGCCAAGTGGACAGATCTTCGTTGATCGCTTCCTCAGCACGCCGATGTTCTACCCGG
CTAACTACGGGTTCATTCCAAATACCTTGAGCGATGACGGCGATCCTTTGGACGTCCTCGTGATTTGCCCTTACCCGGTA
TCACCTGGCGTTGTCATCCGCAGTCGCCCAGTAGGTGTGATGTACATGACGGACGAAGCTGGTGCGGATGCCAAGGTAAT
CGCAGTGCCTCATGAAAAACTCAGCTCTATGTACAGCAATGTAAAGGAATGCTCTGACCTCCCTGCGTTACTCCTCGCAC
AGATTCAGCACTTCTTCGAAAACTACAAAGCGTTAGAGCCGGGTAAGTGGGTGAAAATGGGCCGCTGGGGGAGCGCAGAC
GAAGCGCGGGAAGATATTCGTAAATCGGTAGCGGCCTATAACCTGAAGAAGGAGGCTTCCAAGTAG

Upstream 100 bases:

>100_bases
AAACCTGTTGGACTGGTTACCGTAAAAAAACGAACCACGTATAGCTGTTGGCAAAAACGTCAGTGGCATTGGCCTTTCCT
AGACGCTTGGAGATATGAGC

Downstream 100 bases:

>100_bases
TGTTACTCAATCAGAAAAGCGCAGAGCAGGAAATTTCTCTTAAGGTAAGAGAAGACTTTTTGCTGCTGCCGAAAACTGCT
GAATTGACGCGCTGGGTAAT

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase 2; PPase 2

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSYTDIPAGNAIPDDFFTVIEIPANHSPIKYEVDKPSGQIFVDRFLSTPMFYPANYGFIPNTLSDDGDPLDVLVICPYPV
SPGVVIRSRPVGVMYMTDEAGADAKVIAVPHEKLSSMYSNVKECSDLPALLLAQIQHFFENYKALEPGKWVKMGRWGSAD
EAREDIRKSVAAYNLKKEASK

Sequences:

>Translated_181_residues
MSYTDIPAGNAIPDDFFTVIEIPANHSPIKYEVDKPSGQIFVDRFLSTPMFYPANYGFIPNTLSDDGDPLDVLVICPYPV
SPGVVIRSRPVGVMYMTDEAGADAKVIAVPHEKLSSMYSNVKECSDLPALLLAQIQHFFENYKALEPGKWVKMGRWGSAD
EAREDIRKSVAAYNLKKEASK
>Mature_180_residues
SYTDIPAGNAIPDDFFTVIEIPANHSPIKYEVDKPSGQIFVDRFLSTPMFYPANYGFIPNTLSDDGDPLDVLVICPYPVS
PGVVIRSRPVGVMYMTDEAGADAKVIAVPHEKLSSMYSNVKECSDLPALLLAQIQHFFENYKALEPGKWVKMGRWGSADE
AREDIRKSVAAYNLKKEASK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=169, Percent_Identity=62.7218934911243, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR2_PSESM (Q87WD6)

Other databases:

- EMBL:   AE016853
- RefSeq:   NP_794366.1
- ProteinModelPortal:   Q87WD6
- SMR:   Q87WD6
- GeneID:   1186298
- GenomeReviews:   AE016853_GR
- KEGG:   pst:PSPTO_4615
- TIGR:   PSPTO_4615
- HOGENOM:   HBG529150
- OMA:   YRDEIEN
- ProtClustDB:   CLSK507123
- BioCyc:   PSYR223283:PSPTO_4615-MONOMER
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 20078; Mature: 19947

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTDIPAGNAIPDDFFTVIEIPANHSPIKYEVDKPSGQIFVDRFLSTPMFYPANYGFIP
CCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEHHHHHCCCEECCCCCCCCC
NTLSDDGDPLDVLVICPYPVSPGVVIRSRPVGVMYMTDEAGADAKVIAVPHEKLSSMYSN
CCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCEEEEEECHHHHHHHHHH
VKECSDLPALLLAQIQHFFENYKALEPGKWVKMGRWGSADEAREDIRKSVAAYNLKKEAS
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
SYTDIPAGNAIPDDFFTVIEIPANHSPIKYEVDKPSGQIFVDRFLSTPMFYPANYGFIP
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEHHHHHCCCEECCCCCCCCC
NTLSDDGDPLDVLVICPYPVSPGVVIRSRPVGVMYMTDEAGADAKVIAVPHEKLSSMYSN
CCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCEEEEEECHHHHHHHHHH
VKECSDLPALLLAQIQHFFENYKALEPGKWVKMGRWGSADEAREDIRKSVAAYNLKKEAS
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499