Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 66044380

GI number: 66044380

Start: 1280128

End: 1281294

Strand: Reverse

Name: mdtA [H]

Synonym: Psyr_1129

Alternate gene names: 66044380

Gene position: 1281294-1280128 (Counterclockwise)

Preceding gene: 66044388

Following gene: 66044379

Centisome position: 21.03

GC content: 62.21

Gene sequence:

>1167_bases
ATGCGCAGAAAGACCCTGACCGTCACCGCCGTCGTCCTGGTGATCGCCTGTGCGGCGATTGCCGGCTGGAAACTGACACG
CCCGGCCGCACTCCCCAAAAATGCCGCTGCCGCTGTGCCCGTCAAAGTGATCACGGTCAGCCTTGAAGACGTACCGCGTT
TCGTCACAGGGATCGGATCGGTGCTGTCGCTGCAAAGCGTGGTGATCCGCCCCCAGGTGGATGGGGTGCTGACGCGTGTG
TTGGTCAAGGAAGGTCAGCAGGTCAAGGCCGGGGACCTGCTGGCAACGCTGGATGACCGCTCTATCCGGGCCGCGCTGGA
GCAGGCGCGTGCCCAGTTGGCGCAGAGCAAGGCGCAGCTGGACGTCGCGCAACTGGACCTCAAGCGCTATCGCCAGCTCA
CCCAGGACAATGGCATCTCGCGGCAGACATTCGACCAACAGCAGGCAATGGTCAGGCAACTCGAAGCCACGGCGAAAGGC
AACGAAGCGAGCATCAACGCCTCACAGGTGCAGTTGTCCTACACCCAGATTCGCTCGCCGGTGACGGGACGGGTCGGTAT
TCGCAACGTCGATGAAGGCAACTTCCTGCGCGTCAGCGATGCTGCAGGGCTGTTTTCAGTGACCCAGATCGACCCGATTG
CCGTGGAGTTTTCCCTGCCACAGCAAATGTTGCCGACCCTGCAGGGGCTGATTGCCGAACGTAACGCTGCGACCGTCAAG
GCGTATCAGGGCGACGGCGCGGCCAACGGCCTGCTGCTGGGTGAAGGCACGCTTTCATTGATCGACAATCAGGTGTCGGC
AAGCACCGGTACGATCCGCGCCAAGGCGCAATTCAAAAACCCCGGCGAGCAACTCTGGCCGGGGCAACTGGTGACCGTGA
AGATCCAGACCGGTATCGAACTCAACTCGCTGAAAGTGCCGCCACAAGTGGTGCAGCGCGGCGTTGACCTGCACTTCGTC
TATCGGCTCACTGCCGATAACAAGGTAGAAGTCGTACCCGTCAAAGTGCTCTATCAGGACAGCGAACAGACATTGATCAG
CGGGCCGCGTGCTGGCGATGTACTGGTCAGCGACGGCCAGTCGCGGCTACGCCCCGGCGCAACGGTCGAAGTGATCACCG
CGCCTGCTGCGGATGTCGCGAGCGCGCAAGTGGAGCCCGCACGATGA

Upstream 100 bases:

>100_bases
AAACCTGACAGCTGAAAGTCATTCTGTTGACCGGGTTTGCAGGCTATAAGGAAGCTGTAAAAAACATCTCTCCCGTACCG
ACATTTGGCGTTTTCTTCAT

Downstream 100 bases:

>100_bases
ACGGCCGGGGCTCGGTATCGGCGTGGTGCATCGACCACCCGGTGGCCACCTTGTTGCTGACCTTCGCACTGGTACTGCTG
GGGGTCATTGCCTTTCCACG

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRRKTLTVTAVVLVIACAAIAGWKLTRPAALPKNAAAAVPVKVITVSLEDVPRFVTGIGSVLSLQSVVIRPQVDGVLTRV
LVKEGQQVKAGDLLATLDDRSIRAALEQARAQLAQSKAQLDVAQLDLKRYRQLTQDNGISRQTFDQQQAMVRQLEATAKG
NEASINASQVQLSYTQIRSPVTGRVGIRNVDEGNFLRVSDAAGLFSVTQIDPIAVEFSLPQQMLPTLQGLIAERNAATVK
AYQGDGAANGLLLGEGTLSLIDNQVSASTGTIRAKAQFKNPGEQLWPGQLVTVKIQTGIELNSLKVPPQVVQRGVDLHFV
YRLTADNKVEVVPVKVLYQDSEQTLISGPRAGDVLVSDGQSRLRPGATVEVITAPAADVASAQVEPAR

Sequences:

>Translated_388_residues
MRRKTLTVTAVVLVIACAAIAGWKLTRPAALPKNAAAAVPVKVITVSLEDVPRFVTGIGSVLSLQSVVIRPQVDGVLTRV
LVKEGQQVKAGDLLATLDDRSIRAALEQARAQLAQSKAQLDVAQLDLKRYRQLTQDNGISRQTFDQQQAMVRQLEATAKG
NEASINASQVQLSYTQIRSPVTGRVGIRNVDEGNFLRVSDAAGLFSVTQIDPIAVEFSLPQQMLPTLQGLIAERNAATVK
AYQGDGAANGLLLGEGTLSLIDNQVSASTGTIRAKAQFKNPGEQLWPGQLVTVKIQTGIELNSLKVPPQVVQRGVDLHFV
YRLTADNKVEVVPVKVLYQDSEQTLISGPRAGDVLVSDGQSRLRPGATVEVITAPAADVASAQVEPAR
>Mature_388_residues
MRRKTLTVTAVVLVIACAAIAGWKLTRPAALPKNAAAAVPVKVITVSLEDVPRFVTGIGSVLSLQSVVIRPQVDGVLTRV
LVKEGQQVKAGDLLATLDDRSIRAALEQARAQLAQSKAQLDVAQLDLKRYRQLTQDNGISRQTFDQQQAMVRQLEATAKG
NEASINASQVQLSYTQIRSPVTGRVGIRNVDEGNFLRVSDAAGLFSVTQIDPIAVEFSLPQQMLPTLQGLIAERNAATVK
AYQGDGAANGLLLGEGTLSLIDNQVSASTGTIRAKAQFKNPGEQLWPGQLVTVKIQTGIELNSLKVPPQVVQRGVDLHFV
YRLTADNKVEVVPVKVLYQDSEQTLISGPRAGDVLVSDGQSRLRPGATVEVITAPAADVASAQVEPAR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=339, Percent_Identity=41.5929203539823, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1786668, Length=356, Percent_Identity=30.8988764044944, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789665, Length=321, Percent_Identity=32.0872274143302, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789929, Length=355, Percent_Identity=29.0140845070423, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081951, Length=185, Percent_Identity=31.8918918918919, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081796, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41456; Mature: 41456

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKTLTVTAVVLVIACAAIAGWKLTRPAALPKNAAAAVPVKVITVSLEDVPRFVTGIGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHH
VLSLQSVVIRPQVDGVLTRVLVKEGQQVKAGDLLATLDDRSIRAALEQARAQLAQSKAQL
HHHHHHHEECCCHHHHHHHHHHHCCCCEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
DVAQLDLKRYRQLTQDNGISRQTFDQQQAMVRQLEATAKGNEASINASQVQLSYTQIRSP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEHHHHCCC
VTGRVGIRNVDEGNFLRVSDAAGLFSVTQIDPIAVEFSLPQQMLPTLQGLIAERNAATVK
CCCCCCCEECCCCCEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCEEE
AYQGDGAANGLLLGEGTLSLIDNQVSASTGTIRAKAQFKNPGEQLWPGQLVTVKIQTGIE
EECCCCCCCCEEEECCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCEE
LNSLKVPPQVVQRGVDLHFVYRLTADNKVEVVPVKVLYQDSEQTLISGPRAGDVLVSDGQ
ECCCCCCHHHHHCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEECCCCCCCEEEECCH
SRLRPGATVEVITAPAADVASAQVEPAR
HHCCCCCEEEEEECCCCHHHCCCCCCCC
>Mature Secondary Structure
MRRKTLTVTAVVLVIACAAIAGWKLTRPAALPKNAAAAVPVKVITVSLEDVPRFVTGIGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHH
VLSLQSVVIRPQVDGVLTRVLVKEGQQVKAGDLLATLDDRSIRAALEQARAQLAQSKAQL
HHHHHHHEECCCHHHHHHHHHHHCCCCEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
DVAQLDLKRYRQLTQDNGISRQTFDQQQAMVRQLEATAKGNEASINASQVQLSYTQIRSP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEHHHHCCC
VTGRVGIRNVDEGNFLRVSDAAGLFSVTQIDPIAVEFSLPQQMLPTLQGLIAERNAATVK
CCCCCCCEECCCCCEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCEEE
AYQGDGAANGLLLGEGTLSLIDNQVSASTGTIRAKAQFKNPGEQLWPGQLVTVKIQTGIE
EECCCCCCCCEEEECCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCEE
LNSLKVPPQVVQRGVDLHFVYRLTADNKVEVVPVKVLYQDSEQTLISGPRAGDVLVSDGQ
ECCCCCCHHHHHCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEECCCCCCCEEEECCH
SRLRPGATVEVITAPAADVASAQVEPAR
HHCCCCCEEEEEECCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA