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The map label for this gene is moaC [H]

Identifier: 66044320

GI number: 66044320

Start: 1211047

End: 1211532

Strand: Direct

Name: moaC [H]

Synonym: Psyr_1067

Alternate gene names: 66044320

Gene position: 1211047-1211532 (Clockwise)

Preceding gene: 66044319

Following gene: 66044321

Centisome position: 19.87

GC content: 60.91

Gene sequence:

>486_bases
GTGCTCACTCATCTTGATTCCCAGGGTCGCGCCAATATGGTCGATGTCACGGATAAAGCCGTGACGTCCCGAGAGGCGGT
GGCCGAAGCTTTCGTACGCATGCTGCCGACGACGCTGCAAATGATCGTCAGCGGTGGTCATCCCAAGGGTGACGTGTTTG
CCGTCGCGCGAATCGCCGGCATTCAGGCGGCGAAGAAAACCAGCGATCTGATCCCGCTTTGCCATCCGTTGATGCTCACC
AGCATCAAGGTGCACCTCGCCGCCGAGGGTGATGATGCCGTGCGCATCACCGCGAGCTGCAAGCTGGCCGGGCAGACCGG
TGTGGAAATGGAAGCCCTGACCGCCGCCAGCGTTGCTGCGCTGACCATTTACGATATGTGCAAGGCGGTAGACCGCGGCA
TGGTCATCGAGTCGGTCCGGCTGCTGGAAAAGCTGGGCGGCAAGAGCGGTCACTTCATTGCCGACCAGGCACAGGTTTCC
TCATGA

Upstream 100 bases:

>100_bases
TTCGTACGCTTTAAAACCTGTGTAAAACGCCGGGCACTTTCAGCTTGTAGCTTGCAGCTTGCAGCTGCCACACTTCTTGC
TTCTGCCAAGGAGTAACGTT

Downstream 100 bases:

>100_bases
AGGTTCAGGTTCAGTATTTTGCCCGTTACCGTGAAGTCCTGGGCCTGGACAGCGAGTCCGTTGAAGGCGAGTTCGCCACG
CTGGACGCATTGCGCCAGAC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MLTHLDSQGRANMVDVTDKAVTSREAVAEAFVRMLPTTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
SIKVHLAAEGDDAVRITASCKLAGQTGVEMEALTAASVAALTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVS
S

Sequences:

>Translated_161_residues
MLTHLDSQGRANMVDVTDKAVTSREAVAEAFVRMLPTTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
SIKVHLAAEGDDAVRITASCKLAGQTGVEMEALTAASVAALTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVS
S
>Mature_161_residues
MLTHLDSQGRANMVDVTDKAVTSREAVAEAFVRMLPTTLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLT
SIKVHLAAEGDDAVRITASCKLAGQTGVEMEALTAASVAALTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVS
S

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=68.4210526315789, Blast_Score=199, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI32566331, Length=160, Percent_Identity=38.75, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=54.7297297297297, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=54.014598540146, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16932; Mature: 16932

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHLDSQGRANMVDVTDKAVTSREAVAEAFVRMLPTTLQMIVSGGHPKGDVFAVARIAG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IQAAKKTSDLIPLCHPLMLTSIKVHLAAEGDDAVRITASCKLAGQTGVEMEALTAASVAA
HHHHHHCCCCHHHHHHHHHHHEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
LTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVSS
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCCC
>Mature Secondary Structure
MLTHLDSQGRANMVDVTDKAVTSREAVAEAFVRMLPTTLQMIVSGGHPKGDVFAVARIAG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IQAAKKTSDLIPLCHPLMLTSIKVHLAAEGDDAVRITASCKLAGQTGVEMEALTAASVAA
HHHHHHCCCCHHHHHHHHHHHEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
LTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADQAQVSS
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA