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The map label for this gene is engD [H]

Identifier: 66044194

GI number: 66044194

Start: 1076491

End: 1077591

Strand: Reverse

Name: engD [H]

Synonym: Psyr_0941

Alternate gene names: 66044194

Gene position: 1077591-1076491 (Counterclockwise)

Preceding gene: 66044195

Following gene: 66044191

Centisome position: 17.68

GC content: 59.85

Gene sequence:

>1101_bases
ATGGGATTCAATTGCGGCATCGTCGGCCTGCCTAACGTCGGCAAGTCCACCCTGTTCAACGCCCTGACCAAATCTGGTAT
CGCGGCCGAGAACTTCCCCTTCTGCACCATCGAGCCGAACAGCGGTATCGTGCCGATGCCCGACCCGCGTCTGGCGGCCC
TGGCTGCCATCGTCAACCCGAAACGCATCCTGCCGACCACCATGGAGTTCGTCGACATCGCCGGCCTCGTGGCAGGCGCT
TCGAAGGGCGAAGGCCTGGGCAACAAGTTTCTCGCCAACATCCGCGAGACCGATGCCATCGCCCACGTGGTGCGCTGCTT
TGAAGACGAGAACGTGATTCACGTTTCCAACAGCGTCGACCCCAAGCGCGACATCGAGATCATCGATCTGGAACTGATCT
TCGCCGACCTCGACAGCTGCGAGAAGCAACTGCAAAAGGTCACCCGCAACGCCAAGGGCGGCGACAAGGACGCAGTGGTC
CAGAAAGGCCTGCTGGAACAGTTGATTGCACACTTCAGCGAAGGCAAGCCTGCACGCAGCCTGATGAAGAGCATGAGCAA
CGACGAGAAAGCCACCATCCGTGGCTTCCACCTGCTGACCACCAAGCCGGTCATGTACATCGCCAACGTCGCCGAAGACG
GCTTCGAGAACAACCCGCTGCTGGACGTGGTCCGCGCCATCGCCGAAGAAGAAGGCGCAATGCTGGTGCCGGTCTGCAAC
AAGATCGAAGCCGAAATCGCCGAGCTTGATGACGGCGAAGAGAAAGACATGTTCCTCGAAGCCCTGGGCCTCGAAGAACC
CGGCCTGAACCGCGTGATCCGCGCTGGCTACGAAATGCTCCACCTGCAGACCTACTTCACCGCTGGCGTCGAAGAAGTCC
GCGCCTGGACCGTCCGCGTCGGTGCCACCGCACCACAAGCCGCAGGCGTGATCCACACCGACTTCGAAAAAGGCTTCATC
CGCGCCGAAGTGGTGGCATATGACGACTTCATCCAGTTCAAGGGTGAGTCAGGTGCCAAGGAAGCCGGCAAGTGGCGTCT
GGAAGGCAAGGAATACATCGTCAAGGACGGTGATGTGATGCATTTCCGGTTTAACGTCTGA

Upstream 100 bases:

>100_bases
TGCCCTCGGCGTGCTGCCGGATATCTTCGCCGGTGAATGGAACCGGGCGATGAAAAACCTGCACAGCCAGAAGGCCTGAC
ATCACTCGAGGGGAAACACC

Downstream 100 bases:

>100_bases
TTTGAGCACCTCGCCTCAGGGGCTCTTTGAAACACTGAGCAGCTGCTGAAACCCCGATAAAACCGCACATTTGTGCGGTT
TTATTGTTTCGAGATATCGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLAALAAIVNPKRILPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVTRNAKGGDKDAVV
QKGLLEQLIAHFSEGKPARSLMKSMSNDEKATIRGFHLLTTKPVMYIANVAEDGFENNPLLDVVRAIAEEEGAMLVPVCN
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFI
RAEVVAYDDFIQFKGESGAKEAGKWRLEGKEYIVKDGDVMHFRFNV

Sequences:

>Translated_366_residues
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLAALAAIVNPKRILPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVTRNAKGGDKDAVV
QKGLLEQLIAHFSEGKPARSLMKSMSNDEKATIRGFHLLTTKPVMYIANVAEDGFENNPLLDVVRAIAEEEGAMLVPVCN
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFI
RAEVVAYDDFIQFKGESGAKEAGKWRLEGKEYIVKDGDVMHFRFNV
>Mature_365_residues
GFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLAALAAIVNPKRILPTTMEFVDIAGLVAGAS
KGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVTRNAKGGDKDAVVQ
KGLLEQLIAHFSEGKPARSLMKSMSNDEKATIRGFHLLTTKPVMYIANVAEDGFENNPLLDVVRAIAEEEGAMLVPVCNK
IEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFIR
AEVVAYDDFIQFKGESGAKEAGKWRLEGKEYIVKDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.5652173913043, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI58761502, Length=212, Percent_Identity=40.0943396226415, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=69.672131147541, Blast_Score=529, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=42.0054200542005, Blast_Score=286, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=38.7700534759358, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=34.4736842105263, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24640873, Length=365, Percent_Identity=43.013698630137, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640877, Length=365, Percent_Identity=43.013698630137, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640875, Length=365, Percent_Identity=43.013698630137, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=39.7553516819572, Blast_Score=228, Evalue=7e-60,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40024; Mature: 39893

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLAALAAIVNP
CCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
KRILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVD
HHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PKRDIEIIDLELIFADLDSCEKQLQKVTRNAKGGDKDAVVQKGLLEQLIAHFSEGKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LMKSMSNDEKATIRGFHLLTTKPVMYIANVAEDGFENNPLLDVVRAIAEEEGAMLVPVCN
HHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECHH
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRV
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEE
GATAPQAAGVIHTDFEKGFIRAEVVAYDDFIQFKGESGAKEAGKWRLEGKEYIVKDGDVM
CCCCCCCCCCEEECCCCCCEEEEEEEEEHHHEECCCCCCCCCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
GFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLAALAAIVNP
CCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
KRILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVD
HHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PKRDIEIIDLELIFADLDSCEKQLQKVTRNAKGGDKDAVVQKGLLEQLIAHFSEGKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LMKSMSNDEKATIRGFHLLTTKPVMYIANVAEDGFENNPLLDVVRAIAEEEGAMLVPVCN
HHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECHH
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRV
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEE
GATAPQAAGVIHTDFEKGFIRAEVVAYDDFIQFKGESGAKEAGKWRLEGKEYIVKDGDVM
CCCCCCCCCCEEECCCCCCEEEEEEEEEHHHEECCCCCCCCCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA