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The map label for this gene is aprE [H]

Identifier: 66044189

GI number: 66044189

Start: 1068604

End: 1069926

Strand: Direct

Name: aprE [H]

Synonym: Psyr_0934

Alternate gene names: 66044189

Gene position: 1068604-1069926 (Clockwise)

Preceding gene: 66044188

Following gene: 66044190

Centisome position: 17.54

GC content: 55.56

Gene sequence:

>1323_bases
ATGAGCATTAAGACAATATCCACGCTCGACACGCACGCGGATGACATGCCCACCTCTGATCGCGGGATTCGCCGGATCGG
TGTGACGATCGTACTGGTCACCTTCGGCCTGTTCGGTACCTGGGCAGCGCTGGCCCCATTGGATAATGCGGTGTACGGCT
CGGGTCTGGTAATGGTGCAGAGTTATCGCAAGACGGTTCAACATCTTGAAGGCGGGATCGTCAAGGAACTGCTTGTCCGT
GACGGGGACACCGTGCATAAGGGTGATCCGCTGATCGTATTGGACGACTCGCAGTTGCGCTCCCAATACGAGTCGACCCG
TAATCAGCTGATTTCGACCCAGGCCAGGGAGGCACGACTGCGCGCCGAGCGCGACGAGCTGCCGTCGATTCCGCCACTGA
CCATCACTGGTACGGACAGTGTGCGGGCTAAAGAGGCCATAGCAGGTGAGCAACAGGTATTCAGCACCCGTAAAAACTCG
CGCCTGACCGAGATATCGGTGCAACGTGAACGCATCGGGCAATTGAAGCAGCAGATCAGTGGTCTGCGAGACATGATCCG
CACCAAGGTCAGCCTCGAAAAATCCTACAGCAGCGAAATCACTGAACTGAAGGATCTGCTGTCTCAGGGCTTTGTCGACA
AGCAACGCTTGCTGGAGCAGGAGCGCAAGCTGGACATGCTCAAGTCCGAAGTGGCCGATCACGAGTCCACGATCACCAAG
ACTCAGCTACAGATCAGCGAGACTGAACTGCAGATCATTCAGTTGAACAAAAACTTCAGCTCTGACGTCGCGAAAGAACT
AAGCGATGTACAGGCCAAGGTATTCGATTTGCAGGAGACCGCTAACGCGCTGCAGGACCGTCTGTCTCGCGTGGTCATTC
GGGCTCCTGAGGACGGCATGGTACTGGACATGAAAGTTCATACCGTTGGCGGCGTAGTCAGCGCCGGTACGCCTTTGCTG
GATATCGTGCCGGAATCTTCCGAGCTGGTCGTTGAGGCTCATGTGGCTATCACGGACATTGACCGGATTTCCATCGGCAA
GCTGACAGACGTTCACTTCAGCGCCTTCAACAGTGCTACCACCCCTGTCATCGAGGGTGAGGTGACGCGTATCTCCGCTG
ACCGTTTGAAAGACGATGCCGGTGAGCCGTATTACCTGGTTCGGGTAAAACTGACCGAGAAAGGCATGAAGCGTCTTGGC
GACCGCAAGTTGCAGCCGGGCATGCCCGCTGAAGTGCTGATCAATGCTGGTGAACGGACCATGCTTCAATACCTGTTGAA
GCCGGCGTCCAATGTATTTATCAAATCGATGATCGAGGAATGA

Upstream 100 bases:

>100_bases
GCACAGCAACAGGCCAAAGCGCAGCAGGCTCAGCAACGGGTGGCTCCTGCAGTCACCGGTGTCGGCCCTGCGCAACCTGG
CGCGTGAAAGGAATTCATGA

Downstream 100 bases:

>100_bases
CCGTGCTGCGCTTCGTTCCTGTGTTTCTTTCCCTCGGGTTGGCCAGCATTCAGGTCCATGCAGACCCCACGCAGCCCGCT
GCACCCCAGGTGACCAGCGC

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSIKTISTLDTHADDMPTSDRGIRRIGVTIVLVTFGLFGTWAALAPLDNAVYGSGLVMVQSYRKTVQHLEGGIVKELLVR
DGDTVHKGDPLIVLDDSQLRSQYESTRNQLISTQAREARLRAERDELPSIPPLTITGTDSVRAKEAIAGEQQVFSTRKNS
RLTEISVQRERIGQLKQQISGLRDMIRTKVSLEKSYSSEITELKDLLSQGFVDKQRLLEQERKLDMLKSEVADHESTITK
TQLQISETELQIIQLNKNFSSDVAKELSDVQAKVFDLQETANALQDRLSRVVIRAPEDGMVLDMKVHTVGGVVSAGTPLL
DIVPESSELVVEAHVAITDIDRISIGKLTDVHFSAFNSATTPVIEGEVTRISADRLKDDAGEPYYLVRVKLTEKGMKRLG
DRKLQPGMPAEVLINAGERTMLQYLLKPASNVFIKSMIEE

Sequences:

>Translated_440_residues
MSIKTISTLDTHADDMPTSDRGIRRIGVTIVLVTFGLFGTWAALAPLDNAVYGSGLVMVQSYRKTVQHLEGGIVKELLVR
DGDTVHKGDPLIVLDDSQLRSQYESTRNQLISTQAREARLRAERDELPSIPPLTITGTDSVRAKEAIAGEQQVFSTRKNS
RLTEISVQRERIGQLKQQISGLRDMIRTKVSLEKSYSSEITELKDLLSQGFVDKQRLLEQERKLDMLKSEVADHESTITK
TQLQISETELQIIQLNKNFSSDVAKELSDVQAKVFDLQETANALQDRLSRVVIRAPEDGMVLDMKVHTVGGVVSAGTPLL
DIVPESSELVVEAHVAITDIDRISIGKLTDVHFSAFNSATTPVIEGEVTRISADRLKDDAGEPYYLVRVKLTEKGMKRLG
DRKLQPGMPAEVLINAGERTMLQYLLKPASNVFIKSMIEE
>Mature_439_residues
SIKTISTLDTHADDMPTSDRGIRRIGVTIVLVTFGLFGTWAALAPLDNAVYGSGLVMVQSYRKTVQHLEGGIVKELLVRD
GDTVHKGDPLIVLDDSQLRSQYESTRNQLISTQAREARLRAERDELPSIPPLTITGTDSVRAKEAIAGEQQVFSTRKNSR
LTEISVQRERIGQLKQQISGLRDMIRTKVSLEKSYSSEITELKDLLSQGFVDKQRLLEQERKLDMLKSEVADHESTITKT
QLQISETELQIIQLNKNFSSDVAKELSDVQAKVFDLQETANALQDRLSRVVIRAPEDGMVLDMKVHTVGGVVSAGTPLLD
IVPESSELVVEAHVAITDIDRISIGKLTDVHFSAFNSATTPVIEGEVTRISADRLKDDAGEPYYLVRVKLTEKGMKRLGD
RKLQPGMPAEVLINAGERTMLQYLLKPASNVFIKSMIEE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48863; Mature: 48731

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTISTLDTHADDMPTSDRGIRRIGVTIVLVTFGLFGTWAALAPLDNAVYGSGLVMVQ
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHH
SYRKTVQHLEGGIVKELLVRDGDTVHKGDPLIVLDDSQLRSQYESTRNQLISTQAREARL
HHHHHHHHHCCHHHHHHHHCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RAERDELPSIPPLTITGTDSVRAKEAIAGEQQVFSTRKNSRLTEISVQRERIGQLKQQIS
HHHHHCCCCCCCEEEECCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GLRDMIRTKVSLEKSYSSEITELKDLLSQGFVDKQRLLEQERKLDMLKSEVADHESTITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLQISETELQIIQLNKNFSSDVAKELSDVQAKVFDLQETANALQDRLSRVVIRAPEDGM
HEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCE
VLDMKVHTVGGVVSAGTPLLDIVPESSELVVEAHVAITDIDRISIGKLTDVHFSAFNSAT
EEEEEEEECCCHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHCCCCC
TPVIEGEVTRISADRLKDDAGEPYYLVRVKLTEKGMKRLGDRKLQPGMPAEVLINAGERT
CCEECCCEEEEEHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCCCCCCCHHHEEECCHHH
MLQYLLKPASNVFIKSMIEE
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIKTISTLDTHADDMPTSDRGIRRIGVTIVLVTFGLFGTWAALAPLDNAVYGSGLVMVQ
CCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHH
SYRKTVQHLEGGIVKELLVRDGDTVHKGDPLIVLDDSQLRSQYESTRNQLISTQAREARL
HHHHHHHHHCCHHHHHHHHCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RAERDELPSIPPLTITGTDSVRAKEAIAGEQQVFSTRKNSRLTEISVQRERIGQLKQQIS
HHHHHCCCCCCCEEEECCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GLRDMIRTKVSLEKSYSSEITELKDLLSQGFVDKQRLLEQERKLDMLKSEVADHESTITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLQISETELQIIQLNKNFSSDVAKELSDVQAKVFDLQETANALQDRLSRVVIRAPEDGM
HEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCE
VLDMKVHTVGGVVSAGTPLLDIVPESSELVVEAHVAITDIDRISIGKLTDVHFSAFNSAT
EEEEEEEECCCHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHCCCCC
TPVIEGEVTRISADRLKDDAGEPYYLVRVKLTEKGMKRLGDRKLQPGMPAEVLINAGERT
CCEECCCEEEEEHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCCCCCCCHHHEEECCHHH
MLQYLLKPASNVFIKSMIEE
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]