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The map label for this gene is coaE [H]

Identifier: 66044050

GI number: 66044050

Start: 900795

End: 901418

Strand: Reverse

Name: coaE [H]

Synonym: Psyr_0795

Alternate gene names: 66044050

Gene position: 901418-900795 (Counterclockwise)

Preceding gene: 66044051

Following gene: 66044049

Centisome position: 14.79

GC content: 60.42

Gene sequence:

>624_bases
ATGACTCACCCTGATGAAAAACCCTGGATTCTTGGCCTGACTGGCGGCATCGGTAGCGGTAAAAGTGCAGCGGCGAAGTG
CTTTAGCGACCTTGGCATCGACACTGTGGATGCCGACCATGCCGCCCGCTGGGTAGTCGAGCCCGGGCGCCCGGCGCTGG
AGCAGATAGCGGCGCACTTCGGTAAAGGCGTGCTGCAGACCAGCGGCGAGCTGGACCGTGGCGCGCTGCGCAAGCTGATT
TTCGAAACCCCCGAGCAGCGACGCTGGCTGGAAGCGCTGCTGCATCCGCTGATCAATCAGGAAATCGTCAGCCATCTGGC
CAAGGCCAAATCGCCGTATGCCATTTTGGTCTCGCCACTGCTGGTCGAGTCCGGGCAATACCGCATGGTTCAGCGGCTGC
TGGTGATCGATGCACCGGCGCACCTGCAGATAGAACGCACCATGCTGCGCGACAGCTCTAGCCAGGAGCAGGTCGAAGCC
ATTCTTAAGGTGCAGATCCAGCGTGAAGACCGCCTGCGTCATGCCAATGATGTGCTGGTCAACGACCGCGATCACGCCTG
GCTCAGCAGCGAAGTCGAGCGACTGCACCACTTTTACCTTACTTTGCGTGGAGGCCAATCATGA

Upstream 100 bases:

>100_bases
CGCCGATCCCCTTTGGTCCTTATCTGGCCATTGCGGGGTGGATCGCTTTGCTCTGGGGTGGTCAAATAACCGACTCTTAC
ATGCAGTTTGCCGGTTTCAG

Downstream 100 bases:

>100_bases
GCCAACCAATGACCGTTCAATGCCCAACCTGCGACGCCCCGGTGGAATGGAGCGCAGCCAGCCCGAGCCGTCCGTTTTGC
TCCGAACGCTGCAAACTGAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTHPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHFGKGVLQTSGELDRGALRKLI
FETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPLLVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEA
ILKVQIQREDRLRHANDVLVNDRDHAWLSSEVERLHHFYLTLRGGQS

Sequences:

>Translated_207_residues
MTHPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHFGKGVLQTSGELDRGALRKLI
FETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPLLVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEA
ILKVQIQREDRLRHANDVLVNDRDHAWLSSEVERLHHFYLTLRGGQS
>Mature_206_residues
THPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHFGKGVLQTSGELDRGALRKLIF
ETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPLLVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEAI
LKVQIQREDRLRHANDVLVNDRDHAWLSSEVERLHHFYLTLRGGQS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=208, Percent_Identity=36.0576923076923, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI191252795, Length=208, Percent_Identity=36.0576923076923, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI110227607, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI110227605, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227603, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227601, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI205277394, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=51.0309278350515, Blast_Score=187, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17554944, Length=178, Percent_Identity=31.4606741573034, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=193, Percent_Identity=26.4248704663212, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=32.1243523316062, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644728, Length=178, Percent_Identity=33.1460674157303, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24658602, Length=193, Percent_Identity=26.9430051813472, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23183; Mature: 23052

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHF
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHEEEECCCCHHHHHHHHHH
GKGVLQTSGELDRGALRKLIFETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPL
CCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
LVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEAILKVQIQREDRLRHANDVLV
HHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NDRDHAWLSSEVERLHHFYLTLRGGQS
CCCCCHHHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure 
THPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHF
CCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHEEEECCCCHHHHHHHHHH
GKGVLQTSGELDRGALRKLIFETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPL
CCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
LVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEAILKVQIQREDRLRHANDVLV
HHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NDRDHAWLSSEVERLHHFYLTLRGGQS
CCCCCHHHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA