Click here to switch to the map view.

The map label for this gene is ndh [H]

Identifier: 66044045

GI number: 66044045

Start: 897200

End: 898498

Strand: Reverse

Name: ndh [H]

Synonym: Psyr_0790

Alternate gene names: 66044045

Gene position: 898498-897200 (Counterclockwise)

Preceding gene: 66044046

Following gene: 66044044

Centisome position: 14.74

GC content: 61.66

Gene sequence:

>1299_bases
ATGACGCATCGTATTGTTATCGTTGGCGGAGGCGCTGGCGGTCTGGAGCTGGCTACCAGTCTGGGCAAGACCCTGGGCAA
GAAAGGCACGGCCAGTGTCACGCTGGTTGATGCCAACCTGACGCATATCTGGAAACCGCTGTTGCACGAAGTGGCTGCCG
GTTCGCTCAACTCGTATGAGGACGAGCTGAACTACGTGGCTCAGGCCAAGTGGAACAACTTTCAGTTTCAGCTCGGGCGC
ATGACCGGTCTGGACCGCGCCAGCCGCCAGATTCATCTGGCCGAGACGCTGGATGAAAACGGCGCAGAACTGGTTCCGGC
ACGCAGCCTGGGTTACGACTCGCTGGTCATCGCCGTGGGCAGCACCACCAACGACTTCGGCACCAAGGGCGCGGCAGAGC
ACTGCCTGTTTCTTGACAGCCGCAAACAGGCCGAGCGCTTTCACCAGCAACTGCTCAACCACTACCTGCGCGCCCACGCC
GGCCAGGCCGACAGCGCGCAGGAAATTACCGTGGCCATCGTGGGTGCCGGTGCAACCGGTGTCGAGTTGGCGGCAGAGCT
GCACAACGCGGCACATGAACTGGCGGCTTACGGGCTGGGTCAGATCAAGCCGGAAAACCTGCGCATCACGGTGATCGAAG
CCGGGCCACGGGTGTTGCCCGCGCTGCCCGAGCGCATCGGCGCGCCGGTGCACAAGACGCTGGAAAAACTCGGTGTGACG
GTGCTGACCAATGCGGCAGTCAGTGAGGTGACGGCTGATGGCTTGATCACCGCTACCGGGCAAGTCATCCCGGCCAGCCT
GAAGGTCTGGGCGGCAGGTATTCGTGCCCCGGCCTTCCTGCATGAACTGGATGGTCTGGAAAGCAACCGGATCAATCAGT
TGCAAGTGCTGCCGACGCTGCAAACCACTCGTGACGAAAATATCTTCGCCTTCGGTGACTGCGCGGCCTGCCCGCAAAAA
GGCACCGACCGCAACGTCCCGCCGCGCGCTCAGGCCGCCCACCAGCAGGCATCCTTGCTGGTCAAATCGCTACGCTTGCG
GATTGAAGGCAAGACATTGCCGGAGTACACCTACAAGGACTACGGCTCGCTGATCTCGCTGTCGAGCTTCTCGGCCGTCG
GCAATCTGATGGGTAACCTGATGGGCAGCGTGATGCTTGAAGGCTGGCTGGCGCGGATGTTCTACGTGTCGCTGTACCGC
ATGCACCAGATGGCGCTGTACGGCACCTTCCGTACCCTGATGCTGATGCTGGGCAGCAAGATCGGTAAAGGCACCGAGCC
GCGGATGAAGCTGCACTAA

Upstream 100 bases:

>100_bases
CGTGATGAACCCTTTATTGAGCCTTCTGACGCTATGAGCTGCCTTGCGCTCGCGAAGATCGAGCTCCCCCCGAATTCCTT
AAACCTTCCGAGTAATCCTT

Downstream 100 bases:

>100_bases
GCCACACCAGACGAGAGGCGTACGGGAAAACACTATCGTGCCCATGCTCCGTAGCGTGAGGAACGATCATCTCGACTATC
GTGCGGCGCTCTGCGTCGCA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTHRIVIVGGGAGGLELATSLGKTLGKKGTASVTLVDANLTHIWKPLLHEVAAGSLNSYEDELNYVAQAKWNNFQFQLGR
MTGLDRASRQIHLAETLDENGAELVPARSLGYDSLVIAVGSTTNDFGTKGAAEHCLFLDSRKQAERFHQQLLNHYLRAHA
GQADSAQEITVAIVGAGATGVELAAELHNAAHELAAYGLGQIKPENLRITVIEAGPRVLPALPERIGAPVHKTLEKLGVT
VLTNAAVSEVTADGLITATGQVIPASLKVWAAGIRAPAFLHELDGLESNRINQLQVLPTLQTTRDENIFAFGDCAACPQK
GTDRNVPPRAQAAHQQASLLVKSLRLRIEGKTLPEYTYKDYGSLISLSSFSAVGNLMGNLMGSVMLEGWLARMFYVSLYR
MHQMALYGTFRTLMLMLGSKIGKGTEPRMKLH

Sequences:

>Translated_432_residues
MTHRIVIVGGGAGGLELATSLGKTLGKKGTASVTLVDANLTHIWKPLLHEVAAGSLNSYEDELNYVAQAKWNNFQFQLGR
MTGLDRASRQIHLAETLDENGAELVPARSLGYDSLVIAVGSTTNDFGTKGAAEHCLFLDSRKQAERFHQQLLNHYLRAHA
GQADSAQEITVAIVGAGATGVELAAELHNAAHELAAYGLGQIKPENLRITVIEAGPRVLPALPERIGAPVHKTLEKLGVT
VLTNAAVSEVTADGLITATGQVIPASLKVWAAGIRAPAFLHELDGLESNRINQLQVLPTLQTTRDENIFAFGDCAACPQK
GTDRNVPPRAQAAHQQASLLVKSLRLRIEGKTLPEYTYKDYGSLISLSSFSAVGNLMGNLMGSVMLEGWLARMFYVSLYR
MHQMALYGTFRTLMLMLGSKIGKGTEPRMKLH
>Mature_431_residues
THRIVIVGGGAGGLELATSLGKTLGKKGTASVTLVDANLTHIWKPLLHEVAAGSLNSYEDELNYVAQAKWNNFQFQLGRM
TGLDRASRQIHLAETLDENGAELVPARSLGYDSLVIAVGSTTNDFGTKGAAEHCLFLDSRKQAERFHQQLLNHYLRAHAG
QADSAQEITVAIVGAGATGVELAAELHNAAHELAAYGLGQIKPENLRITVIEAGPRVLPALPERIGAPVHKTLEKLGVTV
LTNAAVSEVTADGLITATGQVIPASLKVWAAGIRAPAFLHELDGLESNRINQLQVLPTLQTTRDENIFAFGDCAACPQKG
TDRNVPPRAQAAHQQASLLVKSLRLRIEGKTLPEYTYKDYGSLISLSSFSAVGNLMGNLMGSVMLEGWLARMFYVSLYRM
HQMALYGTFRTLMLMLGSKIGKGTEPRMKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=430, Percent_Identity=55.3488372093023, Blast_Score=460, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6323794, Length=359, Percent_Identity=25.3481894150418, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323515, Length=447, Percent_Identity=24.3847874720358, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320118, Length=457, Percent_Identity=24.507658643326, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46576; Mature: 46445

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRIVIVGGGAGGLELATSLGKTLGKKGTASVTLVDANLTHIWKPLLHEVAAGSLNSYE
CCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHH
DELNYVAQAKWNNFQFQLGRMTGLDRASRQIHLAETLDENGAELVPARSLGYDSLVIAVG
HHHHHHHHCCCCCEEEEECCCCCCCHHHCEEEEHHHHCCCCCEECCCCCCCCCEEEEEEC
STTNDFGTKGAAEHCLFLDSRKQAERFHQQLLNHYLRAHAGQADSAQEITVAIVGAGATG
CCCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VELAAELHNAAHELAAYGLGQIKPENLRITVIEAGPRVLPALPERIGAPVHKTLEKLGVT
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHCCCC
VLTNAAVSEVTADGLITATGQVIPASLKVWAAGIRAPAFLHELDGLESNRINQLQVLPTL
CEEHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECH
QTTRDENIFAFGDCAACPQKGTDRNVPPRAQAAHQQASLLVKSLRLRIEGKTLPEYTYKD
HCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHH
YGSLISLSSFSAVGNLMGNLMGSVMLEGWLARMFYVSLYRMHQMALYGTFRTLMLMLGSK
HHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGKGTEPRMKLH
CCCCCCCCCCCC
>Mature Secondary Structure 
THRIVIVGGGAGGLELATSLGKTLGKKGTASVTLVDANLTHIWKPLLHEVAAGSLNSYE
CEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHH
DELNYVAQAKWNNFQFQLGRMTGLDRASRQIHLAETLDENGAELVPARSLGYDSLVIAVG
HHHHHHHHCCCCCEEEEECCCCCCCHHHCEEEEHHHHCCCCCEECCCCCCCCCEEEEEEC
STTNDFGTKGAAEHCLFLDSRKQAERFHQQLLNHYLRAHAGQADSAQEITVAIVGAGATG
CCCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VELAAELHNAAHELAAYGLGQIKPENLRITVIEAGPRVLPALPERIGAPVHKTLEKLGVT
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHCCCC
VLTNAAVSEVTADGLITATGQVIPASLKVWAAGIRAPAFLHELDGLESNRINQLQVLPTL
CEEHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECH
QTTRDENIFAFGDCAACPQKGTDRNVPPRAQAAHQQASLLVKSLRLRIEGKTLPEYTYKD
HCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHH
YGSLISLSSFSAVGNLMGNLMGSVMLEGWLARMFYVSLYRMHQMALYGTFRTLMLMLGSK
HHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGKGTEPRMKLH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]