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The map label for this gene is csgA [H]

Identifier: 66043937

GI number: 66043937

Start: 759438

End: 760163

Strand: Reverse

Name: csgA [H]

Synonym: Psyr_0670

Alternate gene names: 66043937

Gene position: 760163-759438 (Counterclockwise)

Preceding gene: 66043938

Following gene: 66043936

Centisome position: 12.47

GC content: 59.5

Gene sequence:

>726_bases
ATGGAGTCTGTCTCTCAATCTGCCAAGGAATCATTCATGACCACTACCAAGAAAACCGCTCTGATCATCGGTGCTTCGCG
TGGCCTGGGGCTAGGGCTGGTGCAGCGCTTGACCGAACAGGGCTGGCACGTCACCGCCACCGTACGTGATCCGCAAAATG
CCGAAAACCTGAAAGCAGTCGAGGGCGTGCGCATCGAGGCGGTGGATCTGGACGAAACGGCTTCGCTTGAAGTGTTGGTC
CAGAAGCTGCGCGGTGAGGTGTTCGACGTGCTGTTTGTCAATGCCGGCATCACCGGTGCGGAACACCAGAGCGCTGCGAA
GTCGACCGCTGCCGAGCTGGGGCAGTTGTTCCTGACCAACGCGGTGGCACCGATTCGTCTGGCCGAGCGCTTCGTCGATC
AACTTCGTCCCGGCACGGGCGTCCTGGCGTTCATGAGTTCGTGGCTGGGCAGCGTCACTTGCCCGGATGGCGCAAACCTT
GCGCTGTACAAGGCCAGCAAGGCCGCGCTCAATTCGATGACCAATACCTTTGTCACCGAGCTGGGCGAAAACCGTCCCAC
TGTGCTGTCGATGCATCCGGGCTGGGTCAAGACCGACATGGGCGGCGAAAATGCTGCCATCGACGTCATGACCAGCACCA
ACGGGCTTGTCGAACAGCTCAATGCCTACGCTGGCAAAGGCGGCCATCACTTCATCGATTATCAGGGCAAGACGATTGCC
TGGTAA

Upstream 100 bases:

>100_bases
CATCTACCTTGAACGTTTTCGGCTCGCGAAGATTCCAACAGGTCATGGGCAGGAGTACGCTGCAAGGTCGAAACTTTCGA
GAGGCCTTGCTGGCACTGCC

Downstream 100 bases:

>100_bases
CCGGCCGCTCGACTAGAATCGCCGTCCTTCGCCGGGGCGTACCTGACCCCGGCAACCCTGGATCAGCAGACAGGGCATCA
CTGAGCTGGCTAACCTGAAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MESVSQSAKESFMTTTKKTALIIGASRGLGLGLVQRLTEQGWHVTATVRDPQNAENLKAVEGVRIEAVDLDETASLEVLV
QKLRGEVFDVLFVNAGITGAEHQSAAKSTAAELGQLFLTNAVAPIRLAERFVDQLRPGTGVLAFMSSWLGSVTCPDGANL
ALYKASKAALNSMTNTFVTELGENRPTVLSMHPGWVKTDMGGENAAIDVMTSTNGLVEQLNAYAGKGGHHFIDYQGKTIA
W

Sequences:

>Translated_241_residues
MESVSQSAKESFMTTTKKTALIIGASRGLGLGLVQRLTEQGWHVTATVRDPQNAENLKAVEGVRIEAVDLDETASLEVLV
QKLRGEVFDVLFVNAGITGAEHQSAAKSTAAELGQLFLTNAVAPIRLAERFVDQLRPGTGVLAFMSSWLGSVTCPDGANL
ALYKASKAALNSMTNTFVTELGENRPTVLSMHPGWVKTDMGGENAAIDVMTSTNGLVEQLNAYAGKGGHHFIDYQGKTIA
W
>Mature_241_residues
MESVSQSAKESFMTTTKKTALIIGASRGLGLGLVQRLTEQGWHVTATVRDPQNAENLKAVEGVRIEAVDLDETASLEVLV
QKLRGEVFDVLFVNAGITGAEHQSAAKSTAAELGQLFLTNAVAPIRLAERFVDQLRPGTGVLAFMSSWLGSVTCPDGANL
ALYKASKAALNSMTNTFVTELGENRPTVLSMHPGWVKTDMGGENAAIDVMTSTNGLVEQLNAYAGKGGHHFIDYQGKTIA
W

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558990, Length=232, Percent_Identity=32.3275862068966, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17558994, Length=241, Percent_Identity=29.8755186721992, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI193207563, Length=228, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17559962, Length=226, Percent_Identity=32.3008849557522, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559964, Length=237, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17532177, Length=241, Percent_Identity=29.8755186721992, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17558992, Length=227, Percent_Identity=30.3964757709251, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72001658, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558996, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=201, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640547, Length=247, Percent_Identity=34.8178137651822, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25722; Mature: 25722

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVSQSAKESFMTTTKKTALIIGASRGLGLGLVQRLTEQGWHVTATVRDPQNAENLKAV
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
EGVRIEAVDLDETASLEVLVQKLRGEVFDVLFVNAGITGAEHQSAAKSTAAELGQLFLTN
CCCEEEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AVAPIRLAERFVDQLRPGTGVLAFMSSWLGSVTCPDGANLALYKASKAALNSMTNTFVTE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEECCCCCCEEEEEHHHHHHHHHHHHHHHH
LGENRPTVLSMHPGWVKTDMGGENAAIDVMTSTNGLVEQLNAYAGKGGHHFIDYQGKTIA
HCCCCCEEEEECCCEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCEEC
W
C
>Mature Secondary Structure
MESVSQSAKESFMTTTKKTALIIGASRGLGLGLVQRLTEQGWHVTATVRDPQNAENLKAV
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
EGVRIEAVDLDETASLEVLVQKLRGEVFDVLFVNAGITGAEHQSAAKSTAAELGQLFLTN
CCCEEEEECCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AVAPIRLAERFVDQLRPGTGVLAFMSSWLGSVTCPDGANLALYKASKAALNSMTNTFVTE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEECCCCCCEEEEEHHHHHHHHHHHHHHHH
LGENRPTVLSMHPGWVKTDMGGENAAIDVMTSTNGLVEQLNAYAGKGGHHFIDYQGKTIA
HCCCCCEEEEECCCEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCEEC
W
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]