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The map label for this gene is pncB [H]

Identifier: 66043862

GI number: 66043862

Start: 682976

End: 684199

Strand: Reverse

Name: pncB [H]

Synonym: Psyr_0595

Alternate gene names: 66043862

Gene position: 684199-682976 (Counterclockwise)

Preceding gene: 66043863

Following gene: 66043861

Centisome position: 11.23

GC content: 58.82

Gene sequence:

>1224_bases
ATGAGCGAGAGCGCCTTTTCCAATCGCATCGTGCAAAGCCTGCTCGATACCGATTTCTACAAGCTGACCATGATGCAGGC
CGTCCTGCACAACTACCCGAACGTGGACGTCGAGTGGGAATTCCGTTGCCGCAACGGGGAGGACCTTCGCCCCTATCTGG
ATGAAATCAAGCACCAGATCGAGCTGTTGTGCGAGCTGTCGCTAAGCCCCGAACATCTGGCCTTTCTGGAACGCATCACC
TTCATCAAACCGGATTTTCTGCGCTTTCTCGGGCTGTTCCGCTTCAATACCCGCTACGTGAAAACCACCATCGAGAATGA
CGAACTGTGCATTCGCCTGCACGGGCCGTGGCTGCACGTCATCCTGTTCGAAGTGCCGCTGCTGGCCATCGTCAGCGAAG
TGCGCAACCGGCATCGCTACCCGGACACCCTGCTCAGCCAGGCGCGGGATCGTCTGTATGACAAGTTCGAATGGTTGACC
ACGCATGCCACGACGGATGAGCTGGCCGAGCTGAAAGTGGCGGACTTCGGCACGCGCCGGCGGTTTTCCTACCGCGTGCA
GGAAGAAATGCTCGGCGTCCTGAAAAACGACTTTCCAGGCCAGTTCGTCGGCACCAGCAATGTGCATCTGGCCCGCCAGC
TTGACCTCAAGCCCTTGGGCACCATGGCCCACGAATGGATCATGGCCCATCAGCAGCTGGGACCGCGTCTGATCGACAGT
CAGATTGCCGCGCTCGATTGCTGGGTCCGTGAATATCGCGGCCTGCTGGGGATCGCGCTGACCGACTGCATCACCACCGA
TGCCTTCCTGAACGACTTCGATCTGTACTTCGCCAAGCTGTTCGACGGTTTGCGCCATGATTCGGGCGACCCGGTGAAGT
GGGCCGAAAAATGCATCTCGCATTACCAGAAGCTCGGTATCGACCCGATGAGCAAGACCCTGGTGTTTTCCGATGGGCTG
AACCTGCCCAAGGCGCTCGATATCTTTCGCGCGTTGCGCGGACGCATCAATGTCAGCTTCGGGATCGGCACCAACCTGAC
GGCCGACATCCCCGGCATTGCGCCGATGAACATGGTATTGAAAATGACGGCTTGCGCCGGTCAGGCCGTGGCGAAGATCT
CTGACGAGCCCGGCAAGACGCAGTGCAAGGACCCGAACTTTGTCGCTTACCTGCGGCATGTGTTCAAGGTGCCGGATTTG
CCGAGCCCGGAAAAACCCGCTTGA

Upstream 100 bases:

>100_bases
AGGGCGACAATGCACACCCATCCGGCCGTGAGCCTTCCATGGTGACAGACAGGAAGTCACGCGCCCCACTTTATCCGGCT
GCTCTGGAGAGCCTGATTCA

Downstream 100 bases:

>100_bases
ATTGTCCTATCTACGAGGAGTGAATCATGCACGCCGTACAGCGCCAGATTGCTGAACAGCTCAAGGTCCAGCCACCTTTC
GCGGACCAGAACGCGCTGCA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIKHQIELLCELSLSPEHLAFLERIT
FIKPDFLRFLGLFRFNTRYVKTTIENDELCIRLHGPWLHVILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLT
THATTDELAELKVADFGTRRRFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDS
QIAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCISHYQKLGIDPMSKTLVFSDGL
NLPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVLKMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDL
PSPEKPA

Sequences:

>Translated_407_residues
MSESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIKHQIELLCELSLSPEHLAFLERIT
FIKPDFLRFLGLFRFNTRYVKTTIENDELCIRLHGPWLHVILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLT
THATTDELAELKVADFGTRRRFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDS
QIAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCISHYQKLGIDPMSKTLVFSDGL
NLPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVLKMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDL
PSPEKPA
>Mature_406_residues
SESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIKHQIELLCELSLSPEHLAFLERITF
IKPDFLRFLGLFRFNTRYVKTTIENDELCIRLHGPWLHVILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLTT
HATTDELAELKVADFGTRRRFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDSQ
IAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCISHYQKLGIDPMSKTLVFSDGLN
LPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVLKMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDLP
SPEKPA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=397, Percent_Identity=50.6297229219144, Blast_Score=400, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6324783, Length=416, Percent_Identity=30.5288461538462, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46678; Mature: 46547

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIKHQI
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
ELLCELSLSPEHLAFLERITFIKPDFLRFLGLFRFNTRYVKTTIENDELCIRLHGPWLHV
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCHHHH
ILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLTTHATTDELAELKVADFGTRR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
RFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDS
HHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHH
QIAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HYQKLGIDPMSKTLVFSDGLNLPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVL
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHH
KMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDLPSPEKPA
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIKHQI
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
ELLCELSLSPEHLAFLERITFIKPDFLRFLGLFRFNTRYVKTTIENDELCIRLHGPWLHV
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCHHHH
ILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLTTHATTDELAELKVADFGTRR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
RFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDS
HHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHH
QIAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HYQKLGIDPMSKTLVFSDGLNLPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVL
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHH
KMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDLPSPEKPA
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA