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The map label for this gene is ygfA [C]

Identifier: 66043586

GI number: 66043586

Start: 335260

End: 335871

Strand: Reverse

Name: ygfA [C]

Synonym: Psyr_0317

Alternate gene names: 66043586

Gene position: 335871-335260 (Counterclockwise)

Preceding gene: 66043587

Following gene: 66043584

Centisome position: 5.51

GC content: 61.76

Gene sequence:

>612_bases
ATGATCAGCGCCCAATCACTCACACGTCCACAATTGCGCCGCCAGCTACGCAAGGCACGCAAAGCCCTGAGTCAAAGCCA
GCAACGCGCAGCCGCACGGGATATTTACCGTCAACTCGCGCAGCACCCGCTGTTTCGGCGTGCACGACATGTTTCGCTGT
ACCTGCCGATGGATGGCGAGATCGACCCGCGGCTGTTGCTGCGCGAAGCACAGCGCCGCGGCAAGGCAACCTATCTGCCG
GTGCTCAATGCCTGGCCGCGCACCCGCATGGTTTTTCAGCGTGTGCGTCCCGGCGAGACATTCATCCCCAACCGTTTCCG
CATCCCCGAGCCGCGCATCGACCGGGCAAGGCAACGCCCTGTCTGGGCGCTCGATCTGATCCTGATGCCGTTGGTAGGTT
TCGATGACGAAGGCGGTCGACTGGGCATGGGCGGAGGTTTCTACGACCGCAGCCTGGCGTACCTGGCGCGCAGAAAGACC
TGGCGCAAACCGCTGTTACTCGGGCTGGCTCATGAATGTCAGAAAGTGGATCGACTGGCGCAGGCCAGTTGGGATGTACC
GCTGCACGGCACGCTATCGGATAAAGGCTGGTATGTGACGCAGACTCTCTGA

Upstream 100 bases:

>100_bases
GAGTCCATATTCGGTCAGTTGCCAGCCCTGTTGTCTGGCAACGACGACCCCGCTCCGGCTTCAACCTCCTTTCCGGATCA
GCCTGCATGACCTCCTGCTC

Downstream 100 bases:

>100_bases
TCGTTCAGCCAACAAGGCCATCAACGATCAGAGTACAGGCAGGGCTCAATGCCTGCCGGGGACTTTTTGCTGCTGCTGTG
TGATCTCGACGGGAGCGTCG

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MISAQSLTRPQLRRQLRKARKALSQSQQRAAARDIYRQLAQHPLFRRARHVSLYLPMDGEIDPRLLLREAQRRGKATYLP
VLNAWPRTRMVFQRVRPGETFIPNRFRIPEPRIDRARQRPVWALDLILMPLVGFDDEGGRLGMGGGFYDRSLAYLARRKT
WRKPLLLGLAHECQKVDRLAQASWDVPLHGTLSDKGWYVTQTL

Sequences:

>Translated_203_residues
MISAQSLTRPQLRRQLRKARKALSQSQQRAAARDIYRQLAQHPLFRRARHVSLYLPMDGEIDPRLLLREAQRRGKATYLP
VLNAWPRTRMVFQRVRPGETFIPNRFRIPEPRIDRARQRPVWALDLILMPLVGFDDEGGRLGMGGGFYDRSLAYLARRKT
WRKPLLLGLAHECQKVDRLAQASWDVPLHGTLSDKGWYVTQTL
>Mature_203_residues
MISAQSLTRPQLRRQLRKARKALSQSQQRAAARDIYRQLAQHPLFRRARHVSLYLPMDGEIDPRLLLREAQRRGKATYLP
VLNAWPRTRMVFQRVRPGETFIPNRFRIPEPRIDRARQRPVWALDLILMPLVGFDDEGGRLGMGGGFYDRSLAYLARRKT
WRKPLLLGLAHECQKVDRLAQASWDVPLHGTLSDKGWYVTQTL

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=179, Percent_Identity=29.608938547486, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1789278, Length=183, Percent_Identity=37.1584699453552, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17510857, Length=193, Percent_Identity=25.9067357512953, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161077430, Length=201, Percent_Identity=27.8606965174129, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23660; Mature: 23660

Theoretical pI: Translated: 11.93; Mature: 11.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAQSLTRPQLRRQLRKARKALSQSQQRAAARDIYRQLAQHPLFRRARHVSLYLPMDGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEECCCCC
IDPRLLLREAQRRGKATYLPVLNAWPRTRMVFQRVRPGETFIPNRFRIPEPRIDRARQRP
CCHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
VWALDLILMPLVGFDDEGGRLGMGGGFYDRSLAYLARRKTWRKPLLLGLAHECQKVDRLA
HHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASWDVPLHGTLSDKGWYVTQTL
HHCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MISAQSLTRPQLRRQLRKARKALSQSQQRAAARDIYRQLAQHPLFRRARHVSLYLPMDGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEECCCCC
IDPRLLLREAQRRGKATYLPVLNAWPRTRMVFQRVRPGETFIPNRFRIPEPRIDRARQRP
CCHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
VWALDLILMPLVGFDDEGGRLGMGGGFYDRSLAYLARRKTWRKPLLLGLAHECQKVDRLA
HHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASWDVPLHGTLSDKGWYVTQTL
HHCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]