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The map label for this gene is exbB [H]

Identifier: 66043406

GI number: 66043406

Start: 145279

End: 145986

Strand: Direct

Name: exbB [H]

Synonym: Psyr_0136

Alternate gene names: 66043406

Gene position: 145279-145986 (Clockwise)

Preceding gene: 66043405

Following gene: 66043407

Centisome position: 2.38

GC content: 63.56

Gene sequence:

>708_bases
ATGAACGCATCGCTCTCTTCCATGATCGTCCCCGCCGTGCTCTGGGCACTGATTCTGTTTTCCGTATTGAGTTGGGCACT
GTTGCTGATCAAGTCGGCGCAGTACGTCCGCCAGAAGTCCCAGAACAAGCAATTCACCAAAGCCTTCTGGAGCGCACCGG
ACCTGCTCACTGCGGCCGAGCACTCCGCGCAATACCCCGGCGCGCTGGCGCGTATTGCCAACAGCGGCTTCGAAGCCATG
GCGGTTGACGAGTCGCCGCGCACCACGCAACAACTGGCGCACACCATCAACCGCTCGGACCGTCTGGAGCGCAACCTGCG
CCAGCAGATACAGAAAGAGCGTCGCGCGCTGGAAAGTGGCCAGGCGATTCTCGCCAGTATCGGCAGCACCGCGCCCTTCA
TCGGCCTGTTCGGTACGGTCTGGGGGATCATGGAAGCGCTGCAAAGCATCGGCGTGACCGGCTCGGCCAGCCTCGAAGCG
GTCGCCGGCCCCATCGGTCATGCGTTGGTCGCCACCGGTGTGGGTATCGCCGTCGCCGTGCCGGCAGTGCTGATCTACAA
CTTCTTCCTGCGCCGCCTCAAGCTCGCCGTGGCCGACATGGATGACTTCGCCCACGACTTCGACGCCCTCGCCCAGCGCA
GCGCCTTTGCCGTTACACGCCAGCCCATCGCCAGCAAGAATGGTCATGCCGTTCGGGAGGCCAGCTAA

Upstream 100 bases:

>100_bases
TAGAAGGCTTCGCGACGCAGACCATCGACTTCAAGTTGCCGGAATGATCCGGCGCATGACAACCGACTATTCAATTATCA
AAGCTGGTGAGGTTTAAACC

Downstream 100 bases:

>100_bases
TGTCTTTCTCCACTCAGGACAGCGATGAAGTGCTCAGCGAAATGAACGTCACGCCGCTGGTCGACGTGATGCTCGTGCTG
CTGGTGGTGTTCATCGTCAC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNASLSSMIVPAVLWALILFSVLSWALLLIKSAQYVRQKSQNKQFTKAFWSAPDLLTAAEHSAQYPGALARIANSGFEAM
AVDESPRTTQQLAHTINRSDRLERNLRQQIQKERRALESGQAILASIGSTAPFIGLFGTVWGIMEALQSIGVTGSASLEA
VAGPIGHALVATGVGIAVAVPAVLIYNFFLRRLKLAVADMDDFAHDFDALAQRSAFAVTRQPIASKNGHAVREAS

Sequences:

>Translated_235_residues
MNASLSSMIVPAVLWALILFSVLSWALLLIKSAQYVRQKSQNKQFTKAFWSAPDLLTAAEHSAQYPGALARIANSGFEAM
AVDESPRTTQQLAHTINRSDRLERNLRQQIQKERRALESGQAILASIGSTAPFIGLFGTVWGIMEALQSIGVTGSASLEA
VAGPIGHALVATGVGIAVAVPAVLIYNFFLRRLKLAVADMDDFAHDFDALAQRSAFAVTRQPIASKNGHAVREAS
>Mature_235_residues
MNASLSSMIVPAVLWALILFSVLSWALLLIKSAQYVRQKSQNKQFTKAFWSAPDLLTAAEHSAQYPGALARIANSGFEAM
AVDESPRTTQQLAHTINRSDRLERNLRQQIQKERRALESGQAILASIGSTAPFIGLFGTVWGIMEALQSIGVTGSASLEA
VAGPIGHALVATGVGIAVAVPAVLIYNFFLRRLKLAVADMDDFAHDFDALAQRSAFAVTRQPIASKNGHAVREAS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=223, Percent_Identity=31.390134529148, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789381, Length=201, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25272; Mature: 25272

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASLSSMIVPAVLWALILFSVLSWALLLIKSAQYVRQKSQNKQFTKAFWSAPDLLTAAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
HSAQYPGALARIANSGFEAMAVDESPRTTQQLAHTINRSDRLERNLRQQIQKERRALESG
HHCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QAILASIGSTAPFIGLFGTVWGIMEALQSIGVTGSASLEAVAGPIGHALVATGVGIAVAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAVLIYNFFLRRLKLAVADMDDFAHDFDALAQRSAFAVTRQPIASKNGHAVREAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNASLSSMIVPAVLWALILFSVLSWALLLIKSAQYVRQKSQNKQFTKAFWSAPDLLTAAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
HSAQYPGALARIANSGFEAMAVDESPRTTQQLAHTINRSDRLERNLRQQIQKERRALESG
HHCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QAILASIGSTAPFIGLFGTVWGIMEALQSIGVTGSASLEAVAGPIGHALVATGVGIAVAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAVLIYNFFLRRLKLAVADMDDFAHDFDALAQRSAFAVTRQPIASKNGHAVREAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]