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The map label for this gene is trkA [H]

Identifier: 66043287

GI number: 66043287

Start: 19329

End: 20702

Strand: Reverse

Name: trkA [H]

Synonym: Psyr_0016

Alternate gene names: 66043287

Gene position: 20702-19329 (Counterclockwise)

Preceding gene: 66043288

Following gene: 66043286

Centisome position: 0.34

GC content: 62.01

Gene sequence:

>1374_bases
GTGAAAATCATCATTCTGGGTGCAGGTCAGGTAGGCGGTACGCTGGCCGAGCATCTGGCGGGCGAAGCCAACGACATCAC
CGTGGTCGACACTGACGGCGACCGGTTGCGCGATCTGGGCGACCGCCTGGACATCCGCACCGTGCAGGGCAAAGGCTCCT
ACCCGGCGGTGTTGCGTCAGGCCGGCGCGGACGACGCCGACATGCTGGTCGCGGTGACCAGCAGCGACGAAGCCAACATG
ATTGCCTGTCAGGTGGCCCATACGCTGTTCCATACGCCGACCAAGATCGCGCGCATCCGTGAAGCGGCGTACCTGACACG
CGCAGGCCTGTTCGATAAAAACGCGATCCCGGTCGACGTACTGATCAGTCCGGAGCAGGTCGTCACCAACTACATCAAGC
GTCTGATCGAGTACCCCGGTGCGCTGCAGGTGATCGATTTCGCCGAAGGCAAAGCGCAACTGGTCGCGGTCAAAGCCTAT
TACGGCGGTGCGCTGGTGGGTCAGCCGCTGCGTCAGCTACGAGCGCACATGCCGAATGTCGAAACGCGCATCGCGGCGAT
CTATCGCCGCGACCGGGCGATACTGCCGCATGGCGACACGGTCATCGAGGCCGACGACGAGGTGTTCTTCATTGCCGCCA
AGGCTGACATTCGCGCCGTGATGGGCGAGCTGCGGCGCCTGGACGAGAACTACAAACGTATCGTCATCGCCGGCGGCGGC
AACATCGGCGAGCGTCTGGCTGAAGCCATCGAAAGCCGCTATCAGGTGAAGATCATCGAAGTGAGCCCGGCGCGCTGCCG
CTATCTGTCGGAACACCTGGACAGCACGGTGGTGCTGCAGGGCAGCTCGTCGGACCGCGACCTGCTGCTGGAAGAAAACA
TCGGCAACACCGACCTGTTCCTGGCGCTGACCAACGACGATGAAGCCAACATCATGTCGTCGCTGCTGGCCAAGCGTCTG
GGCGCACGCAAGGTGATGACGCTGATCAATAACCCGGCCTACGTCGACCTGGTGCAGGGCGGTGAAATCGACGTTGCGGT
CAGCCCGCAACTGGCAACCATCGGCACGCTGCTGGCCCACGTGCGCCGCGGTGATATCGTCAGCGTGCATTCGCTGCGAC
GCGGTGCAGCCGAAGCCATCGAGATCGTCGCTCACGGCGACTCGAAATCCAGCAAGGTCGTCAGCCGTGCGATCAAGGAC
ATCAACCTGCCGACCGGTACGGCAATCGGCGCAGTGATCCGCGACGAACAAGTGCTCATTGCCCATGACATCACGGTGAT
CGAATCCGGTGACCATGTGATCATGTTCCTTGTAGACAAGAAGTGCATCCGCGAGGTCGAGCGGCTGTTTCAGGTCGGCC
TGAGCTTTTTCTGA

Upstream 100 bases:

>100_bases
GTCGCCAGCTGCTGGCCCAGCAAGGCGGCCACGACGGTTTCTACTACGCCAAACTGATCAAGATCGCGGATCAAGATCGC
GGCGGCGCGGGAGTAAGCGC

Downstream 100 bases:

>100_bases
ACCGCTGCTGAACAGGGTGTGACCCTACTGAACCTCTTGCCGGCCGGCCCTGTCGGCAACGCTCGTCGACTCGGGCGAAT
TCTCTCTGAGCCCGTGTATC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKIIILGAGQVGGTLAEHLAGEANDITVVDTDGDRLRDLGDRLDIRTVQGKGSYPAVLRQAGADDADMLVAVTSSDEANM
IACQVAHTLFHTPTKIARIREAAYLTRAGLFDKNAIPVDVLISPEQVVTNYIKRLIEYPGALQVIDFAEGKAQLVAVKAY
YGGALVGQPLRQLRAHMPNVETRIAAIYRRDRAILPHGDTVIEADDEVFFIAAKADIRAVMGELRRLDENYKRIVIAGGG
NIGERLAEAIESRYQVKIIEVSPARCRYLSEHLDSTVVLQGSSSDRDLLLEENIGNTDLFLALTNDDEANIMSSLLAKRL
GARKVMTLINNPAYVDLVQGGEIDVAVSPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEIVAHGDSKSSKVVSRAIKD
INLPTGTAIGAVIRDEQVLIAHDITVIESGDHVIMFLVDKKCIREVERLFQVGLSFF

Sequences:

>Translated_457_residues
MKIIILGAGQVGGTLAEHLAGEANDITVVDTDGDRLRDLGDRLDIRTVQGKGSYPAVLRQAGADDADMLVAVTSSDEANM
IACQVAHTLFHTPTKIARIREAAYLTRAGLFDKNAIPVDVLISPEQVVTNYIKRLIEYPGALQVIDFAEGKAQLVAVKAY
YGGALVGQPLRQLRAHMPNVETRIAAIYRRDRAILPHGDTVIEADDEVFFIAAKADIRAVMGELRRLDENYKRIVIAGGG
NIGERLAEAIESRYQVKIIEVSPARCRYLSEHLDSTVVLQGSSSDRDLLLEENIGNTDLFLALTNDDEANIMSSLLAKRL
GARKVMTLINNPAYVDLVQGGEIDVAVSPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEIVAHGDSKSSKVVSRAIKD
INLPTGTAIGAVIRDEQVLIAHDITVIESGDHVIMFLVDKKCIREVERLFQVGLSFF
>Mature_457_residues
MKIIILGAGQVGGTLAEHLAGEANDITVVDTDGDRLRDLGDRLDIRTVQGKGSYPAVLRQAGADDADMLVAVTSSDEANM
IACQVAHTLFHTPTKIARIREAAYLTRAGLFDKNAIPVDVLISPEQVVTNYIKRLIEYPGALQVIDFAEGKAQLVAVKAY
YGGALVGQPLRQLRAHMPNVETRIAAIYRRDRAILPHGDTVIEADDEVFFIAAKADIRAVMGELRRLDENYKRIVIAGGG
NIGERLAEAIESRYQVKIIEVSPARCRYLSEHLDSTVVLQGSSSDRDLLLEENIGNTDLFLALTNDDEANIMSSLLAKRL
GARKVMTLINNPAYVDLVQGGEIDVAVSPQLATIGTLLAHVRRGDIVSVHSLRRGAAEAIEIVAHGDSKSSKVVSRAIKD
INLPTGTAIGAVIRDEQVLIAHDITVIESGDHVIMFLVDKKCIREVERLFQVGLSFF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=63.7554585152838, Blast_Score=580, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49681; Mature: 49681

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAEHLAGEANDITVVDTDGDRLRDLGDRLDIRTVQGKGSYPAVLRQ
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCHHHHHH
AGADDADMLVAVTSSDEANMIACQVAHTLFHTPTKIARIREAAYLTRAGLFDKNAIPVDV
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
LISPEQVVTNYIKRLIEYPGALQVIDFAEGKAQLVAVKAYYGGALVGQPLRQLRAHMPNV
EECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCH
ETRIAAIYRRDRAILPHGDTVIEADDEVFFIAAKADIRAVMGELRRLDENYKRIVIAGGG
HHHHHHHHHCCCEECCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEECCC
NIGERLAEAIESRYQVKIIEVSPARCRYLSEHLDSTVVLQGSSSDRDLLLEENIGNTDLF
CHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCEEE
LALTNDDEANIMSSLLAKRLGARKVMTLINNPAYVDLVQGGEIDVAVSPQLATIGTLLAH
EEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCEEEEEECCCHHHHHHHHHH
VRRGDIVSVHSLRRGAAEAIEIVAHGDSKSSKVVSRAIKDINLPTGTAIGAVIRDEQVLI
HHCCCEEEHHHHHCCHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHEEECCEEEE
AHDITVIESGDHVIMFLVDKKCIREVERLFQVGLSFF
EEEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAEHLAGEANDITVVDTDGDRLRDLGDRLDIRTVQGKGSYPAVLRQ
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCHHHHHH
AGADDADMLVAVTSSDEANMIACQVAHTLFHTPTKIARIREAAYLTRAGLFDKNAIPVDV
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
LISPEQVVTNYIKRLIEYPGALQVIDFAEGKAQLVAVKAYYGGALVGQPLRQLRAHMPNV
EECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCH
ETRIAAIYRRDRAILPHGDTVIEADDEVFFIAAKADIRAVMGELRRLDENYKRIVIAGGG
HHHHHHHHHCCCEECCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEECCC
NIGERLAEAIESRYQVKIIEVSPARCRYLSEHLDSTVVLQGSSSDRDLLLEENIGNTDLF
CHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCEEE
LALTNDDEANIMSSLLAKRLGARKVMTLINNPAYVDLVQGGEIDVAVSPQLATIGTLLAH
EEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCEEEEEECCCHHHHHHHHHH
VRRGDIVSVHSLRRGAAEAIEIVAHGDSKSSKVVSRAIKDINLPTGTAIGAVIRDEQVLI
HHCCCEEEHHHHHCCHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHEEECCEEEE
AHDITVIESGDHVIMFLVDKKCIREVERLFQVGLSFF
EEEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]