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The map label for this gene is cvrA [H]

Identifier: 161486740

GI number: 161486740

Start: 547715

End: 549457

Strand: Reverse

Name: cvrA [H]

Synonym: Psyr_0502

Alternate gene names: 161486740

Gene position: 549457-547715 (Counterclockwise)

Preceding gene: 66043772

Following gene: 66043768

Centisome position: 9.02

GC content: 62.77

Gene sequence:

>1743_bases
TTGGACGCCACCACCATCAACAGCCTGTTCCTGATCGGCGCGTTGCTGGTAGCCGCAAGCATCCTGGTCAGTTCTCTTTC
GTCGCGCCTGGGCATTCCGATTCTGGTCATTATTCTGGCCGTAGGCATGGTTGCAGGCGTCGATGGCGGCGGGATCATCT
TCGACAACTACGCGACCGCCTACCTGGTCGGCAACCTTGCGCTGGCGGTGATCCTGCTCGACGGCGGGCTGCGAACGCGG
GTGGCCAGTTTCCGGGTTGCACTGTGGCCGGCCTTGTCGCTGGCGACGGTGGGCGTGCTGATCACCACGGTACTGACCGG
CATGATGGCTGCGTGGCTGTTCAATCTCAGCGTTATTCAGGGCCTGTTGATCGGCGCGATCGTCGGCTCCACAGACGCCG
CGGCGGTGTTCTCCCTGCTGGGCGGCAAAGGTTTGAACGAGCGCGTTACCGCCAGCCTCGAGATCGAGTCGGGGAGCAAC
GACCCCATGGCGGTGTTCCTGACTGTCACCCTGATCGGCATGCTCGCCAGCGGTCAGACCGGCTTGCACTGGGGACTGCT
GGGGCACCTGATCCAGGAATTCGGGATCGGCAGCTTCATCGGTCTGGGCGGCGGCTGGATCCTGCTGCAACTGGTCAACC
GCATCAATCTGGCCGCCGGCCTCTACCCGATTCTGGTGATTGCCGGTGGCCTGGCAATCTTCGCCCTGACCAACGCCATC
CACGGCAGCGGCTTTCTCGCGGTCTACCTGTGCGGTCTGGTGCTCGGCAACCGGCCGATTCGCAGTCGCCACGGCATCCT
GCACATGCTCGACGGCATGGCCTGGCTGGCACAGATCGGCATGTTTCTGGTACTGGGCCTGCTGGTCACGCCGCACGATC
TGCTGCCGATTGCGATACCAGCGCTGGGTCTGGCGCTGTGGATGATTCTGGTGGCACGTCCACTGTCGGTGATGGTCGGC
CTGCTGCCGTTCAAGGCCTTCCATGATCGCGAAAAAGCCTTTATCGCCTGGGTCGGACTGCGTGGCGCGGTGCCGATCAT
CCTCGCGGTGTTCCCGCTGATGGCCGGCCTGCCCAATGCGCAGCTGTACTTCAACCTGGCGTTCTTTATCGTGCTGGTTT
CGCTGTTGCTGCAAGGCACTAGCCTGCCGTGGATGGCCAAACTGCTGAAAGTGACGGTTCCGCCTGATCCCGCGCCGATT
TCCCGGGCCGCGCTGGAGGTACACGTCACCAGCGAATGGGAGTTGTTCGTCTACCGCCTGGGCGCTGAAAAGTGGTGCAT
CGGCGCGGCGCTGCGTGAGCTGAAGATGCCGGAAGGCACGCGTATCGCGGCACTGTTCCGCGGCCAGCAACTGCTCCACC
CGTCCGGCAGTACAACCCTGGAAGTCGGTGATCTGCTGTGCGTGATCGGCCACGAACACGACCTTCCAGCGCTGGGCAAA
TTGTTCAGCCAGGCGCCGCAGCGTGGGCTGGACCTGCGTTTCTTCGGCGACTTCGTGCTCGAAGGCGACGCAAGGCTGGG
TGAAGTGGCGGCCCTGTATGGCCTGAAACTCGACGGCATCGACCCTGGAATGCCGCTCAGCCAGTTCATCGTGCAGAAGA
ACCGTGGCGAACCGGTGGTCGGCGACCAGGTTGAATGGAATGGAACTATTTGGACGGTTGCCGTCATGGACGGGAACAAG
ATCCAGAAAGTGGGCGTCAAATTCCCCGAAGGAACCCGCCCGGGCCCCGGACTGTTCCTTTAA

Upstream 100 bases:

>100_bases
ACAGCCAAGCAATTCAACAGGTTAAATCGCTTGGCATGCGGACTGCATGGTCAGTTTTCGCCCCTCTCGTTGCAATTCAG
TTTTCTACGGAGTACCGCCC

Downstream 100 bases:

>100_bases
ACTGCCAACCCACACGTATCATCATGCGACCGGTGTCTATGTTTTCCCTGCGTTCCTTTTGTGCTGCCGCACTGTTTGCG
CTCTGCCTGTCTTCTTTCCC

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATAYLVGNLALAVILLDGGLRTR
VASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSN
DPMAVFLTVTLIGMLASGQTGLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAI
HGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIPALGLALWMILVARPLSVMVG
LLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPI
SRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGK
LFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVVGDQVEWNGTIWTVAVMDGNK
IQKVGVKFPEGTRPGPGLFL

Sequences:

>Translated_580_residues
MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATAYLVGNLALAVILLDGGLRTR
VASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSN
DPMAVFLTVTLIGMLASGQTGLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAI
HGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIPALGLALWMILVARPLSVMVG
LLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPI
SRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGK
LFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVVGDQVEWNGTIWTVAVMDGNK
IQKVGVKFPEGTRPGPGLFL
>Mature_580_residues
MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATAYLVGNLALAVILLDGGLRTR
VASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSN
DPMAVFLTVTLIGMLASGQTGLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAI
HGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIPALGLALWMILVARPLSVMVG
LLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPI
SRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGK
LFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVVGDQVEWNGTIWTVAVMDGNK
IQKVGVKFPEGTRPGPGLFL

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=574, Percent_Identity=67.595818815331, Blast_Score=698, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 61469; Mature: 61469

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCHHH
YLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQ
HHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIGMLASGQT
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
GLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAI
CCHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIP
CCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ALGLALWMILVARPLSVMVGLLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
QLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPISRAALEVHVTSEWELFVYRL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
GAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGK
CCCHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCEEEECCEEEEECCCCCCHHHHH
LFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVV
HHHHCHHCCCCEEEEEEEEEECCCCHHHHHHHHCEEECCCCCCCCHHHHHHHCCCCCCCC
GDQVEWNGTIWTVAVMDGNKIQKVGVKFPEGTRPGPGLFL
CCCEEECCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCHHH
YLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQ
HHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIGMLASGQT
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
GLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAI
CCHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIP
CCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ALGLALWMILVARPLSVMVGLLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
QLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPISRAALEVHVTSEWELFVYRL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
GAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGK
CCCHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCEEEECCEEEEECCCCCCHHHHH
LFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVV
HHHHCHHCCCCEEEEEEEEEECCCCHHHHHHHHCEEECCCCCCCCHHHHHHHCCCCCCCC
GDQVEWNGTIWTVAVMDGNKIQKVGVKFPEGTRPGPGLFL
CCCEEECCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA