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The map label for this gene is trxB1 [H]

Identifier: 62391823

GI number: 62391823

Start: 3151416

End: 3151790

Strand: Reverse

Name: trxB1 [H]

Synonym: cg3299

Alternate gene names: 62391823

Gene position: 3151790-3151416 (Counterclockwise)

Preceding gene: 62391826

Following gene: 62391822

Centisome position: 96.01

GC content: 57.07

Gene sequence:

>375_bases
ATGGCAACCATCGATGTAACCGAAGAAACATTTGAGAGCACAGTTACCGGCGACGGAATTGTCCTCGTAGACGCATGGGC
ATCCTGGTGCGGACCTTGCCGCCAGTTCGCCCCAACCTACGAGAAGGTTTCCGAAACCCACACCGACGCAACCTTCGCCA
AGCTTGATACCGAAGCAAACCAGGGCCTGGCTGCAGCACTGCAGATCCAGTCCATCCCAACTCTGATGGTTTTCCGCGAC
GGCATCATGGTCTACCGCGAAGCCGGCACCATGCCAGCTCCTGCACTGGATGATCTGGTCAACCAGGTTAAGGCACTCGA
CATGGATGACGTTCGTCGCCAGGTCGCAGAGCAGCAGGGTTCTGCAGAGGCATAA

Upstream 100 bases:

>100_bases
AGCTGCCGGTCAATGAAGAAAATCCTTGGCCGGGAATAACTACAGTCCGCTGAAAGTTGGTCTATATATAGACCTTACAA
ATCTTGAACGGAGATTCTTA

Downstream 100 bases:

>100_bases
GCTTCCAATTGTGTTTTGGTGAAAACCGCTGAGGAGAACTTCTTCTCGGCGGTTTTCGTCCTTTTTGGGAGCTTTGGGGT
CTTGCGGCTTTTGAGGCTTT

Product: thioredoxin

Products: NA

Alternate protein names: Trx-2; Protein-disulfide reductase [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEANQGLAAALQIQSIPTLMVFRD
GIMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQGSAEA

Sequences:

>Translated_124_residues
MATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEANQGLAAALQIQSIPTLMVFRD
GIMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQGSAEA
>Mature_123_residues
ATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEANQGLAAALQIQSIPTLMVFRDG
IMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQGSAEA

Specific function: Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=101, Percent_Identity=38.6138613861386, Blast_Score=86, Evalue=5e-19,
Organism=Escherichia coli, GI87082331, Length=100, Percent_Identity=35, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17510299, Length=105, Percent_Identity=36.1904761904762, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17554386, Length=96, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=93, Percent_Identity=38.7096774193548, Blast_Score=77, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321648, Length=78, Percent_Identity=42.3076923076923, Blast_Score=77, Evalue=6e-16,
Organism=Drosophila melanogaster, GI18859803, Length=124, Percent_Identity=31.4516129032258, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 13455; Mature: 13324

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEAN
CCCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCC
QGLAAALQIQSIPTLMVFRDGIMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQG
CCHHHHHHHCCCCCHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
SAEA
CCCC
>Mature Secondary Structure 
ATIDVTEETFESTVTGDGIVLVDAWASWCGPCRQFAPTYEKVSETHTDATFAKLDTEAN
CCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCC
QGLAAALQIQSIPTLMVFRDGIMVYREAGTMPAPALDDLVNQVKALDMDDVRRQVAEQQG
CCHHHHHHHCCCCCHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
SAEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]