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The map label for this gene is udgA2 [H]

Identifier: 62391687

GI number: 62391687

Start: 3008743

End: 3010062

Strand: Reverse

Name: udgA2 [H]

Synonym: cg3154

Alternate gene names: 62391687

Gene position: 3010062-3008743 (Counterclockwise)

Preceding gene: 62391688

Following gene: 62391682

Centisome position: 91.69

GC content: 57.95

Gene sequence:

>1320_bases
ATGCGGATGACAGTGATTGGTACGGGTTACCTTGGCGCTACGCACGCGGCCTGCATGGCTGAGCTTAGCCATGAGGTTCT
TGGTGTTGATGTCGATGAGGCAAAGATTGCGTCGTTGAAGGACAGCAAGGTCCCATTTTTTGAGCCGGGTTTGCCTGAGG
TTTTGGAGCGCAATCTGGAAAATGGTCGCCTGAACTTCACTACTGATTATGCGGAGGCTGCGGCTTTCGCGCAGGTGCAT
TTCTTGGGCGTGGGTACTCCTCAGCAGAAGGGTACTTATGCGGCGGATCTGACGTATGTTCGTCAGGTTGTTGAGGATTT
GGTGCCGCTGCTTGAGGGCGAGCACATTATTTTCGGCAAGTCTACGGTTCCGGTTGGTACTGCTGAGCAGTTGCAGGAGC
TTGCTGATTCTCTGGTCAAGCCTGGTTCGCACGTGGAGATCGCGTGGAATCCGGAGTTCTTGCGTGAGGGCTACGCGGTC
AAAGACACCATCACTCCGGACCGCATCGTGGTGGGTGTGCGTGAGGGGGCGACAGCAGAGGCGATCGCTCGCGAGGTTTA
CGCCACCGCGATTGCTGCCGATACCCCATTTTTGGTGACTGATCTTGCTACCGCTGAGCTGGTGAAAGTTTCCGCGAATG
CGTTCTTGGCCACCAAGATTTCCTTCATCAATGCGGTCGCTGAGATTTGTGAGCAGACCGGCGCCGATGTGGTTGCGCTT
GCGGATGCCATCGGTCACGACGATCGTATCGGCCGAAAGTTCTTAGGCGCGGGCCTGGGATTCGGTGGCGGTTGTTTGCC
TAAAGACATCCGCGCTTTCATGGCACGCGCGGGCGAATTGGGTGCTGACCAGGCATTAACGTTCTTGCGTGAGGTCGATT
CCATCAATATGCGTCGTCGCGACCGTGTGGTGCAGCTGGCCAAAGAGATGTGTGGCGGTTCGCTGCTGGGCAAGCGGGTT
ACAGTGCTCGGCGCCGCATTCAAACCCAACTCGGACGATGTCCGCGATTCTCCGGCGCTGTCGGTCGCGGGTTCGCTGTC
GCTCCAGGGTGCGGCGGTCTCGGTCTACGACCCGGAAGCTATGGACAACGCTCGACGCGTCTTCCCGACGCTCAGCTATG
CGTCCAGCACTAAAGAGGCGCTTATCGACGCCCACCTCGTCGTTCTTGCCACTGAATGGCAAGAATTCCGCGACCTTGAC
CCCGAAGTGGCGGGAGGGGTCGTCGAGAAGCGCGCTATTATTGATGGCCGAAACGTCCTCGATGTTGCCAAATGGAAGGC
CGCCGGTTGGGAAATGGAAGCGCTCGGCCGCAACCTTTAG

Upstream 100 bases:

>100_bases
TTCCCCAACAAGTAAGCAATCATGTGTTCCGGTCGCGGGCTGTATCAAAACGTGTTGAGATAATCTCCAGTCCACTCTTC
ATTGAAAGGAATCACCCTAC

Downstream 100 bases:

>100_bases
TGGCGGTGGATCAGGCGGGGCTTGCCATCATCTGGGGCAGGCTCATCGCCGGGTACCGTCCATGCGGCGATCAGCGTCGT
GATCGGCACCGCCAGTGTCA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRMTVIGTGYLGATHAACMAELSHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVREGATAEAIAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRV
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PEVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL

Sequences:

>Translated_439_residues
MRMTVIGTGYLGATHAACMAELSHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVREGATAEAIAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRV
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PEVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL
>Mature_439_residues
MRMTVIGTGYLGATHAACMAELSHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVREGATAEAIAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRV
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PEVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=33.3333333333333, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI296040438, Length=365, Percent_Identity=33.6986301369863, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI296040443, Length=314, Percent_Identity=33.1210191082803, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI48994968, Length=433, Percent_Identity=26.5588914549654, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=27.7008310249307, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=33.9130434782609, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI17136908, Length=462, Percent_Identity=34.1991341991342, Blast_Score=254, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46984; Mature: 46984

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTVIGTGYLGATHAACMAELSHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLE
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
NGRLNFTTDYAEAAAFAQVHFLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGK
CCEEEEEECHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAVKDTITPDRIVVGVREGATAE
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEECCCCCCEEEEEECCCCHHH
AIAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
ADAIGHDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRR
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
DRVVQLAKEMCGGSLLGKRVTVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEA
HHHHHHHHHHCCCHHHCCEEEEEEEECCCCCCCCCCCCCCEEECCCEECCCEEEEECCHH
MDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLDPEVAGGVVEKRAIIDGRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHCCHHHHHHHCCCCCHH
DVAKWKAAGWEMEALGRNL
HHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MRMTVIGTGYLGATHAACMAELSHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLE
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
NGRLNFTTDYAEAAAFAQVHFLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGK
CCEEEEEECHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAVKDTITPDRIVVGVREGATAE
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEECCCCCCEEEEEECCCCHHH
AIAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
ADAIGHDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRR
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
DRVVQLAKEMCGGSLLGKRVTVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEA
HHHHHHHHHHCCCHHHCCEEEEEEEECCCCCCCCCCCCCCEEECCCEECCCEEEEECCHH
MDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLDPEVAGGVVEKRAIIDGRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHCCHHHHHHHCCCCCHH
DVAKWKAAGWEMEALGRNL
HHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]