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The map label for this gene is cysH [H]

Identifier: 62391652

GI number: 62391652

Start: 2975756

End: 2976541

Strand: Reverse

Name: cysH [H]

Synonym: cg3116

Alternate gene names: 62391652

Gene position: 2976541-2975756 (Counterclockwise)

Preceding gene: 62391653

Following gene: 62391651

Centisome position: 90.67

GC content: 56.36

Gene sequence:

>786_bases
ATGAGCTTTCAACTAGTTAACGCCCTGAAAAATACTGGTTCGGTAAAAGATCCCGAGATCTCACCCGAAGGACCTCGCAC
GACCACACCGTTGTCACCAGAGGTAGCAAAACATAACGAGGAACTCGTCGAAAAGCATGCTGCTGCGTTGTATGACGCCA
GCGCGCAAGAGATCCTGGAATGGACAGCCGAGCACGCGCCGGGCGCTATTGCAGTGACCTTGAGCATGGAAAACACCGTG
CTGGCGGAGCTGGCTGCGCGGCACCTGCCGGAAGCTGATTTCCTCTTTTTGGACACCGGTTACCACTTCAAGGAGACCCT
TGAAGTTGCCCGTCAGGTAGATGAGCGCTATTCCCAGAAGCTTGTCACCGCGCTGCCGATCCTCAAGCGCACGGAGCAGG
ATTCCATTTATGGTCTCAACCTGTACCGCAGCAACCCAGCGGCGTGCTGCCGAATGCGCAAAGTTGAACCGCTGGCGGCG
TCGTTAAGCCCATACGCTGGCTGGATCACCGGCCTGCGCCGCGCTGATGGCCCAACCCGTGCTCAAGCCCCTGCGCTGAG
CTTGGATGCCACCGGCAGGCTCAAGATTTCTCCAATTATCACCTGGTCATTGGAGGAAACCAACGAGTTCATTGCGGACA
ACAACCTCATCGATCACCCACTTACCCATCAGGGTTATCCATCAATTGGATGCGAAACCTGCACCCTTCCTGTTGCTGAA
GGACAAGACCCTAGGGCCGGCCGTTGGGCTGGAAACGCCAAGACAGAATGCGGACTTCACTCATGA

Upstream 100 bases:

>100_bases
ACGGCCAGGACGATCCAGTGCACAGGCCAGCACCAGCAAAGTCCACATCGCAAGCATTAAAAGAATCTCTCGAAAGACAC
AAAAGAGGTGAGTCGCAACA

Downstream 100 bases:

>100_bases
CCACAACCGTTGCATCAGTACTATCCCCACACCTTAAAGATCTTGAAAATGAATCCATCCACATCCTCCGCGAGGTAGCT
GGCCAGTTTGATAAGGTCGG

Product: phosphoadenosine-phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSFQLVNALKNTGSVKDPEISPEGPRTTTPLSPEVAKHNEELVEKHAAALYDASAQEILEWTAEHAPGAIAVTLSMENTV
LAELAARHLPEADFLFLDTGYHFKETLEVARQVDERYSQKLVTALPILKRTEQDSIYGLNLYRSNPAACCRMRKVEPLAA
SLSPYAGWITGLRRADGPTRAQAPALSLDATGRLKISPIITWSLEETNEFIADNNLIDHPLTHQGYPSIGCETCTLPVAE
GQDPRAGRWAGNAKTECGLHS

Sequences:

>Translated_261_residues
MSFQLVNALKNTGSVKDPEISPEGPRTTTPLSPEVAKHNEELVEKHAAALYDASAQEILEWTAEHAPGAIAVTLSMENTV
LAELAARHLPEADFLFLDTGYHFKETLEVARQVDERYSQKLVTALPILKRTEQDSIYGLNLYRSNPAACCRMRKVEPLAA
SLSPYAGWITGLRRADGPTRAQAPALSLDATGRLKISPIITWSLEETNEFIADNNLIDHPLTHQGYPSIGCETCTLPVAE
GQDPRAGRWAGNAKTECGLHS
>Mature_260_residues
SFQLVNALKNTGSVKDPEISPEGPRTTTPLSPEVAKHNEELVEKHAAALYDASAQEILEWTAEHAPGAIAVTLSMENTVL
AELAARHLPEADFLFLDTGYHFKETLEVARQVDERYSQKLVTALPILKRTEQDSIYGLNLYRSNPAACCRMRKVEPLAAS
LSPYAGWITGLRRADGPTRAQAPALSLDATGRLKISPIITWSLEETNEFIADNNLIDHPLTHQGYPSIGCETCTLPVAEG
QDPRAGRWAGNAKTECGLHS

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=224, Percent_Identity=29.4642857142857, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325425, Length=220, Percent_Identity=34.0909090909091, Blast_Score=118, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28541; Mature: 28410

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQLVNALKNTGSVKDPEISPEGPRTTTPLSPEVAKHNEELVEKHAAALYDASAQEILE
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WTAEHAPGAIAVTLSMENTVLAELAARHLPEADFLFLDTGYHFKETLEVARQVDERYSQK
HHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LVTALPILKRTEQDSIYGLNLYRSNPAACCRMRKVEPLAASLSPYAGWITGLRRADGPTR
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCC
AQAPALSLDATGRLKISPIITWSLEETNEFIADNNLIDHPLTHQGYPSIGCETCTLPVAE
CCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
GQDPRAGRWAGNAKTECGLHS
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFQLVNALKNTGSVKDPEISPEGPRTTTPLSPEVAKHNEELVEKHAAALYDASAQEILE
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WTAEHAPGAIAVTLSMENTVLAELAARHLPEADFLFLDTGYHFKETLEVARQVDERYSQK
HHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LVTALPILKRTEQDSIYGLNLYRSNPAACCRMRKVEPLAASLSPYAGWITGLRRADGPTR
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCC
AQAPALSLDATGRLKISPIITWSLEETNEFIADNNLIDHPLTHQGYPSIGCETCTLPVAE
CCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
GQDPRAGRWAGNAKTECGLHS
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA