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The map label for this gene is trmH [C]

Identifier: 62391607

GI number: 62391607

Start: 2930133

End: 2930801

Strand: Reverse

Name: trmH [C]

Synonym: cg3070

Alternate gene names: 62391607

Gene position: 2930801-2930133 (Counterclockwise)

Preceding gene: 62391608

Following gene: 62391606

Centisome position: 89.28

GC content: 58.3

Gene sequence:

>669_bases
TTGGACTCAACTAACACCCCCGGCCCCACGGAGTGGGGCGAGTCCCGCGTGGGCAAAGGTCCATGGGAAGAGGAAAACCC
CGGCGTACCTCGGCCTACAAGCCCGCTTTTCGACGTCACCCTCCTCAACGAGGGCGATCGCCGCAACGTTGTTGACGCCT
ATCGTTATTGGACCCGTGAGGCGATTGTTGAAGATATCGACACCCGCCGCCACAGCCTCCACGTAGCGATCGAAAACTTT
GAAAACGACGCCAACATCGGCACCGTCGTGCGCACCGCCAACGCCTTTGCCGTGAACACAGTCCACATTGTGGGCAGGCG
TCGGTGGAACCGCAGGGGAGCCATGGTGACTGACCGTTACCAGCACCTCATGCACCACGAAGACGTTGATTCGCTGCTTG
CGTGGGCAATCGCGGAGCGGCTTACCATCGTCGCGATCGATAACACCCCAGGTTCCGTGCCTTTGGAAACCGCTGAGTTG
CCGAAGAACTGCCTGTTGCTGTTTGGTCAGGAAGGCCCAGGTGTCACCGAAGCTGCGCGTGCAGGTGCGTTAATGACCTG
TTCGATTGCCCAATTTGGTTCCACTCGATCCATCAACGCGGGTGTAGCTGCTGGTATTGCAATGCATGCATGGATTCGTC
AACATGCCGACTTATCGCAAGCCTGGTAA

Upstream 100 bases:

>100_bases
GTTGTGGGCGTTGCCACCGTGGTCGATCGCGCAACCGGTGCAGATGAGGTTATCGCAGCGGAAGGCCTTCCTTACCGCAG
CTTGCTGGGACTTTCTGATC

Downstream 100 bases:

>100_bases
TTTTATACCCTAGATCGTTAGACTTTCGTTATACTTTTGGGTGTCGTATTTAGTTGTACAACACCTGCATTGGAGCGAAG
AAACACTCAGTGTTAGACAA

Product: SPOU rRNA methylase family protein

Products: S-adenosyl-L-homocysteine; tRNATyr Containing 2'-O-methylguanosine [C]

Alternate protein names: RNA Methyltransferase; rRNA Methylase; TRNA/RRNA MethyltransferaU; RNA Methyltransferase TrmH Family; 23S RRNA Methyltransferase; TrmH Family RNA Methyltransferase; RNA Methylase Family Protein; Spou RRNA Methylase Family Protein; Methyltransferase; SPOU RRNA Methylase Family Protein

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MDSTNTPGPTEWGESRVGKGPWEEENPGVPRPTSPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENF
ENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAERLTIVAIDNTPGSVPLETAEL
PKNCLLLFGQEGPGVTEAARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW

Sequences:

>Translated_222_residues
MDSTNTPGPTEWGESRVGKGPWEEENPGVPRPTSPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENF
ENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAERLTIVAIDNTPGSVPLETAEL
PKNCLLLFGQEGPGVTEAARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW
>Mature_222_residues
MDSTNTPGPTEWGESRVGKGPWEEENPGVPRPTSPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENF
ENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAERLTIVAIDNTPGSVPLETAEL
PKNCLLLFGQEGPGVTEAARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW

Specific function: Specifically Methylates Guanosine-18 In Various tRNAs. [C]

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.34 [C]

Molecular weight: Translated: 24546; Mature: 24546

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTNTPGPTEWGESRVGKGPWEEENPGVPRPTSPLFDVTLLNEGDRRNVVDAYRYWTRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
AIVEDIDTRRHSLHVAIENFENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRY
HHHHHHHHHHHEEEEEEECCCCCCCHHHEEEECCCEEEEEEEEEECHHHCCCCCCHHHHH
QHLMHHEDVDSLLAWAIAERLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVTEAAR
HHHHHHCCHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHH
AGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW
CCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MDSTNTPGPTEWGESRVGKGPWEEENPGVPRPTSPLFDVTLLNEGDRRNVVDAYRYWTRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
AIVEDIDTRRHSLHVAIENFENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRY
HHHHHHHHHHHEEEEEEECCCCCCCHHHEEEECCCEEEEEEEEEECHHHCCCCCCHHHHH
QHLMHHEDVDSLLAWAIAERLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVTEAAR
HHHHHHCCHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHH
AGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW
CCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; tRNATyr [C]

Specific reaction: S-Adenosyl-L-methionine + tRNATyr = S-adenosyl-L-homocysteine + tRNATyr Containing 2'-O-methylguanosine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA