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The map label for this gene is nagA1 [H]

Identifier: 62391484

GI number: 62391484

Start: 2787387

End: 2788553

Strand: Reverse

Name: nagA1 [H]

Synonym: cg2929

Alternate gene names: 62391484

Gene position: 2788553-2787387 (Counterclockwise)

Preceding gene: 62391488

Following gene: 62391483

Centisome position: 84.95

GC content: 53.56

Gene sequence:

>1167_bases
ATGGCAGAAGTGGTGCATTATCAAGAAAATGCAGGTCAAGCAGTTAAAAAAATTGAAGGAAGAATTGTTACCCCCCACGG
GGTGATTGATGGCTTTCTCCAACTCGAAAACGGCATCATCACGGAACTCTCTGGAGAACCAGCACCTAAAAACGCAGGAT
TCCACCCCGAACTCCCCACGATTGTTCCCAGTTTTATTGATCTTCATAATCACGGTGGAAACGGTGGCGCGTTTCCTACG
GGAACGCAGGACCAGGCGAGGAATGCCGCGCAGTATCACCGCGAACATGGCACGACCGTGATGTTGGCAAGCATGGTTTC
GGCGCCGGCTGACGCACTGGCAGCGCAGGTGGAAAACCTTATTCCCTTGTGTGAAGAGGGCCTGCTGTGCGGCATTCACC
TCGAGGGTCCTTTCATCAACGCATGCCGTTGTGGTGCTCAAAACCCGGATTTTATTTTTCCCGGCAACCCAACAGATCTT
GCCCAGGTGATCCATGCGGGAAAAGGTTGGATCAAATCGATCACAGTAGCGCCGGAAACTGACAATCTTACTGAGCTTCT
CGATCTCTGCGCAGCGCACCACATCATTGCTTCCTTCGGGCACACTGATGCAGATTTTGATACCACTACCAGCGCAATTG
CCTTGGCTAAAGAGAAAAATGTGACGGTCACGGCTACGCATTTGTTCAATGCGATGCCTCCGCTGCATCATAGGGATCCC
GGCAGCGTGGGCGCTTTGCTTGCTGCGGCACGTGCCGGGGACGCATATGTTGAGTTGATCGCCGACGGCGTGCATTTGGC
CGATGGAACGGTCGATCTAGCTCGTTCCAACAACGCCTTTTTCATCACGGACGCCATGGAAGCCGCCGGAATGCCAGACG
GTGAGTACATTTTGGGCGTTTTGAACGTCACCGTCACCGATGGCGTCGCCCGTCTGCGCGATGGCGGCGCCATCGCCGGG
GGTACCAGCACACTAGCGAGTCAGTTCGTGCACCACGTGCGCAGGGGTATGACGCTTATCGACGCGACCCTCCACACCTC
AACCGTCGCCGCCAAAATTCTCGGACTTAGCGATCACGAAATCGTTAAATCCAACCCTGTAAATTTTGTGGTCTTTGACT
CAAACGGCCAGTTACAACAGGTCCATTTAGACCATCAAGTAATTTAA

Upstream 100 bases:

>100_bases
AACAGCAGGCCTCAAGTCCGAAGATAATTAACCTAAATCCGTAGACATAAGACATCATACGTCCTATGCTTGCTGGAAGG
AAGCAAATAACCTCAGAAAG

Downstream 100 bases:

>100_bases
ATACGAGCAAAACTTTCCTGATAATAAAAGGAGTCCGACCATGGACATCATCATCTGCAAAGACGAGCAAGAAGTCGGCA
AAGCAGCGGCAGCCCTGATC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPSFIDLHNHGGNGGAFPT
GTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDL
AQVIHAGKGWIKSITVAPETDNLTELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRDP
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAG
GTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIVKSNPVNFVVFDSNGQLQQVHLDHQVI

Sequences:

>Translated_388_residues
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPSFIDLHNHGGNGGAFPT
GTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDL
AQVIHAGKGWIKSITVAPETDNLTELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRDP
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAG
GTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIVKSNPVNFVVFDSNGQLQQVHLDHQVI
>Mature_387_residues
AEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPSFIDLHNHGGNGGAFPTG
TQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLA
QVIHAGKGWIKSITVAPETDNLTELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRDPG
SVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAGG
TSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIVKSNPVNFVVFDSNGQLQQVHLDHQVI

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=266, Percent_Identity=32.7067669172932, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI224922791, Length=266, Percent_Identity=32.7067669172932, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786892, Length=345, Percent_Identity=24.9275362318841, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17553768, Length=335, Percent_Identity=28.6567164179104, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19920392, Length=277, Percent_Identity=30.6859205776173, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281361140, Length=290, Percent_Identity=29.6551724137931, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40905; Mature: 40773

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPT
CCCEEEEHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHH
IVPSFIDLHNHGGNGGAFPTGTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHH
IPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLAQVIHAGKGWIKSITVAPET
HHHHCCCCEEEEEECCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCC
DNLTELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRDP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCEEEEHHHHHHCCCCCCCCCC
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGV
CHHHHHHHHHHCCHHHHHHHHCCEEECCCCEEEEECCCEEEEEECHHHCCCCCCCEEEEE
LNVTVTDGVARLRDGGAIAGGTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHE
EEEEEHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
IVKSNPVNFVVFDSNGQLQQVHLDHQVI
HHCCCCCEEEEECCCCCEEEEECCCCCC
>Mature Secondary Structure 
AEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPT
CCEEEEHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHH
IVPSFIDLHNHGGNGGAFPTGTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHH
IPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLAQVIHAGKGWIKSITVAPET
HHHHCCCCEEEEEECCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCC
DNLTELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRDP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCEEEEHHHHHHCCCCCCCCCC
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGV
CHHHHHHHHHHCCHHHHHHHHCCEEECCCCEEEEECCCEEEEEECHHHCCCCCCCEEEEE
LNVTVTDGVARLRDGGAIAGGTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHE
EEEEEHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
IVKSNPVNFVVFDSNGQLQQVHLDHQVI
HHCCCCCEEEEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]