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The map label for this gene is nagB [H]

Identifier: 62391483

GI number: 62391483

Start: 2786585

End: 2787346

Strand: Reverse

Name: nagB [H]

Synonym: cg2928

Alternate gene names: 62391483

Gene position: 2787346-2786585 (Counterclockwise)

Preceding gene: 62391484

Following gene: 62391482

Centisome position: 84.91

GC content: 52.36

Gene sequence:

>762_bases
ATGGACATCATCATCTGCAAAGACGAGCAAGAAGTCGGCAAAGCAGCGGCAGCCCTGATCGCACCCTTCGCAACTAAGGG
CGGAACCTTGGGGCTTGCAACTGGATCGTCACCTTTGAGCACCTACCAAGAGCTCATTCGCATGTATGAAGCTGGGGAAG
TGTCATTCAAGAACTGCAAGGCATTCTTGTTGGATGAATACGTGGGATTAACGCGCGACGATGAAAACAGCTACTTCAAA
ACCATTCGTAAAGAGTTCACTGACCACATCGACATCGTTGATGAAGAGGTCTACAGCCCAGATGGTGCAAACCCTGATCC
ATACGAAGCAGCTGCAGAGTATGAGGCAAAGATCGCTGCAGAATCCGTTGATGTTCAAATCCTTGGCATCGGCGGAAACG
GCCACATCGCTTTCAATGAGCCATCATCTTCTCTGTCAGGACTGACAAAGGTCCAGGCGCTGCACCCTAAAACTGTGGAG
GACAACGCTCGATTCTTCAACACCATCGAAGAGGTCCCAACCCACGCCCTCACCCAGGGTTTGGGCACTTTGTCCCGCGC
GCAAAACATCGTGTTGGTGGCAACTGGTGAAGGAAAAGCCGACGCCATCCGCGGAACTGTGGAAGGCCCACTGACCGCCA
TGTGCCCAGGTTCCATCCTGCAGATGCACAACAATGCCACCATCATCGTTGATGAAGCAGCAGCATCCAAGCTGGAAAAC
GCTGATCACTACCGTCTCATGGAGCAATTAAAGCTGCGCTAG

Upstream 100 bases:

>100_bases
GTGGTCTTTGACTCAAACGGCCAGTTACAACAGGTCCATTTAGACCATCAAGTAATTTAAATACGAGCAAAACTTTCCTG
ATAATAAAAGGAGTCCGACC

Downstream 100 bases:

>100_bases
AAACAAAAAGGAAAGTAGTGTGTGGGGCTATGCACACAGAACTTTCCAGTTTGCGCCCTGCGTACCATGTGACTCCTCCG
CAGGGCAGGCTCAATGATCC

Product: N-acetylglucosamine-6-phosphate isomerase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCKAFLLDEYVGLTRDDENSYFK
TIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAAESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVE
DNARFFNTIEEVPTHALTQGLGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLEN
ADHYRLMEQLKLR

Sequences:

>Translated_253_residues
MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCKAFLLDEYVGLTRDDENSYFK
TIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAAESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVE
DNARFFNTIEEVPTHALTQGLGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLEN
ADHYRLMEQLKLR
>Mature_253_residues
MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCKAFLLDEYVGLTRDDENSYFK
TIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAAESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVE
DNARFFNTIEEVPTHALTQGLGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLEN
ADHYRLMEQLKLR

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=248, Percent_Identity=39.5161290322581, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI19923881, Length=213, Percent_Identity=39.4366197183099, Blast_Score=144, Evalue=6e-35,
Organism=Escherichia coli, GI1786893, Length=248, Percent_Identity=38.3064516129032, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI48994958, Length=247, Percent_Identity=26.7206477732794, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789530, Length=219, Percent_Identity=24.6575342465753, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554876, Length=247, Percent_Identity=40.8906882591093, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24581960, Length=248, Percent_Identity=40.3225806451613, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19920764, Length=248, Percent_Identity=40.3225806451613, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 27278; Mature: 27278

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCK
CEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
AFLLDEYVGLTRDDENSYFKTIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEE
ESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVEDNARFFNTIEEVPTHALTQG
CEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLEN
HHHHHHCCCEEEEEECCCCCHHEECCCCCCEEECCCHHHEEECCCCEEEEECHHHHHHCC
ADHYRLMEQLKLR
CHHHHHHHHHCCC
>Mature Secondary Structure
MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCK
CEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHH
AFLLDEYVGLTRDDENSYFKTIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEE
ESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVEDNARFFNTIEEVPTHALTQG
CEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLEN
HHHHHHCCCEEEEEECCCCCHHEECCCCCCEEECCCHHHEEECCCCEEEEECHHHHHHCC
ADHYRLMEQLKLR
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA