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The map label for this gene is kstD [H]

Identifier: 62391454

GI number: 62391454

Start: 2757962

End: 2758912

Strand: Reverse

Name: kstD [H]

Synonym: cg2898

Alternate gene names: 62391454

Gene position: 2758912-2757962 (Counterclockwise)

Preceding gene: 62391455

Following gene: 62391453

Centisome position: 84.04

GC content: 56.78

Gene sequence:

>951_bases
GTGGTGCTGGCAGCAGGTGGATTCTCCCAGAATCCAGAACTGCGCAAGAAGTACATGCCAGAACCCACCCCACAGTTCTC
CCGCACCAACGAAAGCGCCACCGGCGACACCATGGCCCTTGCTGCGAAAGTGGGAGCACGCCTAGGCGACGACAACGGTG
AAAACGCACTGTGGTTCCCATCGTCCATCGGCACCCGCGCCGACGGATCCACCGCGGTGTACCCACACATTTGGGACCGT
GGCCGCCTCGGAGTCATCGCAGTCAACGCAGCAGGCGAGCGTTTCGTCGATGAATCCGTCTCCTACCACCGCTTCGTGCG
CGCCATGTACGAATCCAACAAAACCACCCCGACTGTTTCAGCCTGGCTCATTGTTGATTCCCACACCCTGGCAAAATACG
GCCTCGGCATGATCACCATGCCACACCTGCCTAAACTCGCTCTGCAAAAATACATCGACTCCGGATACCTGCACGCAGGA
TCATCCTTGGATGAATTGGCACGCAGCATTGGTGTGGACGCTCGCGGCCTGGAACAAACCGTCAAACGCTACAATACCTT
CGCTAAAACGGGTATCGACGAAGACTTCCACAAGGGCGAACTCCTCTTCGGTCAAGCCGCCGGCGATCCAGACAACAAGC
CAAACCCCAACGTCGGACCAATCAAGAAGGGACCGTTCTACGCAATCGCTGTAGTCCCAACCCCTCTGGCCACTGCCTTT
GGCATCAGCATCAACCCCAACGGACAGGTTGTTAGTGAAGATGGGGAGCCCATCATTGGACTGTACTCCGCAGGAAATGA
TGCCCAATCTGTCATGGCTTCTGAATATCCTGGTGCTGGTTCACAGGTTGGTTCCGGAATGACCTTTGGTTGGATCGCAG
CACAGCACGCGGTGGGGAAAGCGGGAAAATCCGGAGGAGCTAAGGCAGGATATGCCGCGTCTTCTAAGTAA

Upstream 100 bases:

>100_bases
CGAGGATCAGCCAGCAAGTTAATGATCCTTACATGGCGCTGTTGTTGGCGCGGTAGTCAATCATGGGGGAGTATCCCACC
GTATCCGCGTGAACAAGGGC

Downstream 100 bases:

>100_bases
TTGCTTGGTGGGTTGCTTACTAGTCCGATGATCGTGAGGGAAACCAGCAGAGCAGCACACAGTACAGAAGCTGGCTTAAA
CCTTATTTGTAGTTGTCAAT

Product: 3-ketosteroid dehydrogenase

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKVGARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDR
GRLGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVSAWLIVDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAG
SSLDELARSIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFGQAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAF
GISINPNGQVVSEDGEPIIGLYSAGNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGKAGKSGGAKAGYAASSK

Sequences:

>Translated_316_residues
MVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKVGARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDR
GRLGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVSAWLIVDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAG
SSLDELARSIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFGQAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAF
GISINPNGQVVSEDGEPIIGLYSAGNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGKAGKSGGAKAGYAASSK
>Mature_316_residues
MVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKVGARLGDDNGENALWFPSSIGTRADGSTAVYPHIWDR
GRLGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVSAWLIVDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAG
SSLDELARSIGVDARGLEQTVKRYNTFAKTGIDEDFHKGELLFGQAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAF
GISINPNGQVVSEDGEPIIGLYSAGNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGKAGKSGGAKAGYAASSK

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 3-keto-1,4- diene-steroid from 3-keto-4-ene-steroid [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 33313; Mature: 33313

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKVGARLGDDNGENALWFP
CEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECC
SSIGTRADGSTAVYPHIWDRGRLGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVS
CCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
AWLIVDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAGSSLDELARSIGVDARGLEQT
EEEEEECCHHHHHCCCEEECCCCHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCHHHHHH
VKRYNTFAKTGIDEDFHKGELLFGQAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAF
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHE
GISINPNGQVVSEDGEPIIGLYSAGNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGK
EEEECCCCCEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHC
AGKSGGAKAGYAASSK
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVLAAGGFSQNPELRKKYMPEPTPQFSRTNESATGDTMALAAKVGARLGDDNGENALWFP
CEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECC
SSIGTRADGSTAVYPHIWDRGRLGVIAVNAAGERFVDESVSYHRFVRAMYESNKTTPTVS
CCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
AWLIVDSHTLAKYGLGMITMPHLPKLALQKYIDSGYLHAGSSLDELARSIGVDARGLEQT
EEEEEECCHHHHHCCCEEECCCCHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCHHHHHH
VKRYNTFAKTGIDEDFHKGELLFGQAAGDPDNKPNPNVGPIKKGPFYAIAVVPTPLATAF
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHE
GISINPNGQVVSEDGEPIIGLYSAGNDAQSVMASEYPGAGSQVGSGMTFGWIAAQHAVGK
EEEECCCCCEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHC
AGKSGGAKAGYAASSK
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12218036 [H]